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Exploring the anesthetic potential of propofol in Ictalurus punctatus (Rafinesque, 1818)

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Abstract

The aim of the present study was to evaluate propofol as an anesthetic and its effects on physiology and histology in Ictalurus punctatus. To determine the ideal concentration, juvenile of I. punctatus (96.60 ± 27.70 g) were used, submitted to different concentrations of the anesthetic: 1.5, 2.0, 2.5, 3.0, 4.0, 5.0, and 6.0 mg L−1. The concentration evaluated as ideal was 2.5 mg L−1. To evaluate the physiological and histological effects of propofol exposure, juvenile of I. punctatus (99.71 ± 26.38 g) were sampled immediately (T0) and 30 min after anesthesia (T30) with 2.5 mg L−1, had blood, liver, and gill samples collected. The exposure of the animals to propofol in both treatments (T0 and T30) caused increases in plasma glucose and lactate levels (p < 0.05) but prevented an increase in cortisol (p > 0.05). The histological study showed mild to moderate changes in the gills (congestion in the lamellar vessels and central vein and epithelial elevation) and moderate and severe changes in the liver (congestion and degeneration). This study concludes that the concentration of 2.5 mg L−1 of propofol provides safe anesthesia for I. punctatus and prevents increased plasma cortisol levels.

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Authors and Affiliations

  1. Laboratório de Aquicultura, Instituto Federal de Educação, Ciência E Tecnologia Catarinense, Araquari, SC, 89245-000, Brazil

    Fabiano de Lima Matter, Eduardo da Silva, Gabriel Tobias Deschamps, Fernanda Thaynnan Rodrigues Santos, Juliano Pereira Terra, Carlos Eduardo Nogueira Martins & Robilson Antônio Weber

  2. Quality Assessoria Veterinária. R. Santa Luzia, 100 - Trindade, Florianópolis, SC, 88036-540, Brazil

    Fabiano de Lima Matter

  3. Centro Universitário Avantis (UNIAVAN) – Balneário Camboriú, Av. Marginal Leste, Estados, Balneário Camboriú, SC, 88339-125, Brazil

    Eduardo da Silva

  4. Laboratório de Diagnóstico Patológico Veterinário (LDPV), Universidade de Brasília, Brasília, Distrito Federal, 70910-900, Brazil

    Juliano Pereira Terra

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  1. Fabiano de Lima Matter
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Contributions

F.L.M: Conceptualization, Methodology, Validation, Resources, Investigation, Resources, Data Curation, Writing—Original Draft, Writing—Review &; Editing, Visualization, Project administration;

E.S; G.T.D and J.P.T: Conceptualization, Methodology, Validation, Investigation, Resources, Data Curation, Writing—Review &; Editing, Visualization;

F.T: Conceptualization, Methodology, Validation, Investigation, Resources, Data Curation, Visualization;

C.E.N.M: Conceptualization, Methodology, Validation, Formal analysis, Investigation, Resources, Data Curation, Writing—Review &; Editing, Visualization, Supervision;

R.A.W: Conceptualization, Methodology, Validation, Investigation, Resources, Data Curation, Writing—Review &; Editing, Visualization, Supervision, Project administration.

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Correspondence to Eduardo da Silva.

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Matter, F.d.L., da Silva, E., Deschamps, G.T. et al. Exploring the anesthetic potential of propofol in Ictalurus punctatus (Rafinesque, 1818). Aquacult Int (2024). https://doi.org/10.1007/s10499-024-01493-5

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