Abstract
This cross-sectional study evaluates the prevalence and factors associated with sleep disturbances in French adult HIV-infected outpatients. Patients fullfilled a self-administered questionnaire on their health behavior, sleep attitudes (Pittsburgh sleep quality index, PSQI), quality of life and depression; 1354 patients were enrolled. Median sleeping time was 7 h. Poor sleep quality was observed in 47 % of the patients, and moderate to serious depressive symptoms in 19.7 %. Factors significantly associated with sleep disturbances were depression, male gender, active employment, living single, tobacco-smoking, duration of HIV infection, nevirapine or efavirenz-including regimen. Prevalence of poor sleepers is high in this HIV adult outpatient population. Associated factors seem poorly specific to HIV infection and more related to social and psychological status. Taking care of these disturbances may prove to be an effective health management strategy.
Resumen
Este estudio transversal evalúa la prevalencia y los factores asociados con los trastornos del sueño en adultos franceses pacientes en ambulatorio infectados por el VIH. Los pacientes completan un auto-cuestionario sobre su comportamiento de salud, las actitudes del sueño (Pittsburgh Sleep Quality Index, PSQI), la calidad de vida y la depresión; 1354 pacientes fueron incluidos. La mediana del tiempo de sueño fue de 7 horas. La malacalidad del sueño se observó en el 47 % de los pacientes, y moderados a graves síntomas depresivos en 19,7 % de los pacientes. Los factores asociados significativamente con las alteraciones del sueño son: la depresión, el sexo masculino, trabajador activo, viviendo solo, fumador, la duración de la infección VIH, tratamiento nevirapina o efavirenz. La prevalencia de los trastornos del sueño es alta en esta población de pacientes adultos VIH en ambulatorio. Los factores asociados parecen poco relacionados a la infección VIH y más relacionados con el estatus social y psicológico. El cuidado de estos trastornos puede ser una estrategia eficaz en la gestión de la salud.
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Acknowledgments
The authors are grateful to Thomas Jovelin for the data management, all the medical staff and all the patients that participated to the study. All authors contributed to the content of the manuscript and agreed with the decision to submit it for publication.
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The members of COREVIH-Pays de la Loire Troubles du Sommeil Study Group are listed in Appendix.
Appendix
Appendix
Study group: F. Raffi, E. Billaud, V. Reliquet, C. Allavena, C. Brunet-Cartier, B. Bonnet, P. Morineau-Le Houssine, S. Bouchez, M. Lefebvre, D. Boutoille, S. Pineau, C. Biron, M. Brière, M. Besnier, F. Sauser, P. Point, O. Aubry, O. Grossi, B. Gout, M. Colas, C. Supiot, H. Hüe, D. Brosseau, L. Larmet, J. Orain, S. Sécher-Pineau, T. Jovelin (Nantes); J.M. Chennebault, V. Rabier, P. Fialaire, Y.M. Vandamne, P. Abgueguen, S. Rehaiem (Angers); P. Perré, T. Guimard, S. Léautez, J.L. Esnault, O. Bollengier-Stragier, I. Suaud, L. Lainé, H. Durand, C. Garnier (La Roche sur Yon); H. Hitoto, L. Perez, I. Ali (Le Mans); C. Michau (Saint Nazaire); R. Vatan (Laval).
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Allavena, C., Guimard, T., Billaud, E. et al. Prevalence and Risk Factors of Sleep Disturbance in a Large HIV-Infected Adult Population. AIDS Behav 20, 339–344 (2016). https://doi.org/10.1007/s10461-015-1160-5
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DOI: https://doi.org/10.1007/s10461-015-1160-5