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Xanthogranulomatous pyelonephritis in children: diagnostic and therapeutic aspects

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Abstract

Xanthogranulomatous pyelonephritis (XGP) is a rare, chronic inflammatory disease of the kidneys. It is characterized by destruction of renal parenchyma and accumulation of lipid-laden foamy macrophages. Diffuse and focal forms are known. The condition is mainly observed in middle-aged women, and it is very rare in childhood. Of 32 nephrectomies carried out in children for various diseases in our hospital over the course of 2 years, there were two cases of diffuse XGP. In both cases, the preoperative diagnosis based on ultrasound findings was highly suggestive of XGP. We present the two cases and define the typical ultrasonographic signs for distinguishing XGP from other renal masses. The diagnostic and therapeutic management is discussed and an overview of the literature is given.

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Author notes

  1. Felicitas Eckoldt

    Present address: Klinik für Kinderchirurgie der FSU Jena, Erlanger Allee 101, 07740, Jena, Germany

Authors and Affiliations

  1. Klinik für Kinderchirurgie, Otto-Heubner-Centrums für Kinder- und Jugendmedizin der Charité, Universitätsmedizin in Berlin, Berlin, Germany

    Felicitas Eckoldt & Stefan Wolke

  2. Abteilung Pädiatrische Radiologie Institut of Diagnostik and Interventional Radiology der Charité, Berlin, Germany

    Thomas Riebel

Authors
  1. Felicitas Eckoldt
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  2. Thomas Riebel
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  3. Stefan Wolke
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Correspondence to Felicitas Eckoldt.

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Eckoldt, F., Riebel, T. & Wolke, S. Xanthogranulomatous pyelonephritis in children: diagnostic and therapeutic aspects. J Med Ultrasonics 36, 33–37 (2009). https://doi.org/10.1007/s10396-008-0201-3

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  • DOI: https://doi.org/10.1007/s10396-008-0201-3

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