Abstract
Hemangiopericytomas are rare vascular tumors that may be associated with profound hypoglycemia. We present correlative imaging findings for a 57-year-old woman who had multiple abdominal and muscular metastases with severe hypoglycemia 11 years after resection of meningeal hemangiopericytoma. The metastases were well-defined masses containing solid and cystic components, and they were extremely hypervascular in the solid component. Those characteristics on imaging associated with hypoglycemia and the past history of meningeal hemangiopericytoma may suggest the diagnosis and be helpful in differentiating the mass from other vascular tumors. Color and power Doppler ultrasound may play a valuable role in characterizing and diagnosing metastasis from hemangiopericytoma. A delay of several years between diagnosis of the primary hemangiopericytoma and the manifestation of metastasis appears to be a special feature of hemangiopericytoma.
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References
F Grunenberger P Bachellier MP Chenard et al. (1987) ArticleTitleHepatic and pulmonary metastases from a meningeal hemangiopericytoma and severe hypoglycemia due to abnormal secretion of insulin-like growth factor: a case report Cancer 85 2245–8
JR Goellner ER Laws SuffixJr EH Soule et al. (1978) ArticleTitleHemangiopericytoma of the meninges. Mayo Clinic experience Am J Clin Pathol 70 375–80 Occurrence Handle707404 Occurrence Handle1:STN:280:CSaD3sbhs1M%3D
AP Stout MR Murray (1942) ArticleTitleHemangiopericytoma: a vascular tumor featuring Zimmermann's pericytes Ann Surg 116 26–33
D Kehagias A Gouliamos L Vlahos (1999) ArticleTitleMR appearance of pelvic hemangiopericytoma Eur Radiol 9 163–5 Occurrence Handle9933402 Occurrence Handle1:STN:280:DyaK1M7jt1GjtA%3D%3D
BR Grimsley BW Loggie IR Goco (1997) ArticleTitleHemangiopericytoma: an unusual cause of upper gastrointestinal hemorrhage Am Surg 63 248–51 Occurrence Handle9036893 Occurrence Handle1:STN:280:ByiC1cfjtVw%3D
VA Ahern SJ Roberts (1991) ArticleTitleHemangiopericytoma – Queensland Radium Institute experience and a review of the literature Australas Radiol 35 245–52
B Mortele M Lemmerling P Seynaeve et al. (2001) ArticleTitleHemangiopericytoma of the parotid gland: CT and MR features Eur Radiol 11 1073–5 Occurrence Handle11419156 Occurrence Handle1:STN:280:DC%2BD38%2FhsVemsQ%3D%3D
F Ferrozzi S Armeroli M Pedrazzini et al. (2001) ArticleTitleDuodenal hemangiopericytoma CT and MRI findings Clin Imaging 25 101–3 Occurrence Handle11483418 Occurrence Handle1:STN:280:DC%2BD3MvjslGhuw%3D%3D
JH Kim HW Jung YS Kim et al. (2003) ArticleTitleMeningeal hemangiopericytomas: long-term outcome and biological behavior Surg Neurol 59 47–54 Occurrence Handle12633961
D Kabus GS Sidha Wieczorek Rl et al. (1993) ArticleTitleMetastatic meningioma. Hemangiopericytoma or angioblastic meningioma? Am J Surg Pathol 17 1144–50 Occurrence Handle8214259 Occurrence Handle1:STN:280:ByuD38jlsFE%3D
M Hara M Aoyagi G Nagashima et al. (1998) ArticleTitleRecurrence in meningeal hemangiopericytoma Surg Neurol 50 586–91 Occurrence Handle9870821 Occurrence Handle1:STN:280:DyaK1M%2Fos1elug%3D%3D
T Kaneko A Harada K Isshiki et al. (1993) ArticleTitleHemangiopericytomatous meningioma metastasized to the liver: report of a case and review of the literature Surg Today 23 644–8 Occurrence Handle8369618 Occurrence Handle10.1007/BF00311916 Occurrence Handle1:STN:280:ByyA2sbktFw%3D
J Woitzik C Sommer JK Krauss (2003) ArticleTitleDelayed manifestation of spinal metastasis: a special feature of hemangiopericytoma Clin Neurol Neurosurg 105 159–66 Occurrence Handle12860507 Occurrence Handle10.1016/S0303-8467(02)00140-3
G Hollmann F Hopner R Daum M Stuhlinger (1971) ArticleTitleClinical aspects of hemangiopericytoma Langenbecks Arch Chir 330 128–39 Occurrence Handle5157363 Occurrence Handle10.1007/BF01234135 Occurrence Handle1:STN:280:CS2C3cvosFM%3D
S Matsuda M Usui H Sakurai et al. (2001) ArticleTitleInsulin-like growth factor II-producing intra-abdominal hemangiopericytoma associated with hypoglycemia J Gastroenterol 36 851–5 Occurrence Handle11777215 Occurrence Handle10.1007/s005350170009 Occurrence Handle1:STN:280:DC%2BD38%2FkvF2ntQ%3D%3D
I Fukuda N Hizika K Takaro (1993) ArticleTitleCharacterization of insulin-like growth factor II (IGF-II) and IGF binding proteins in patients with non-islet-cell tumor hypoglycemia Endocr J 40 111–9 Occurrence Handle7524924 Occurrence Handle1:CAS:528:DyaK3sXmsVKrurY%3D
K Hoekman JV Doorn T Gloudemans et al. (1999) ArticleTitleHypoglycemia associated with the production of insulin-like growth factor II and insulin-like growth factor binding protein 6 by a hemangiopericytoma Clin Endocrinol 51 247–53 Occurrence Handle10.1046/j.1365-2265.1999.00833.x Occurrence Handle1:STN:280:DC%2BD3c%2Fgt1ersg%3D%3D
JD Teale V Marks (1998) ArticleTitleGlucocorticoid therapy suppresses abnormal secretion of big IGF-II by non-islet cell tumors including hypoglycemia Clin Endocrinol (Oxf) 49 491–8 Occurrence Handle10.1046/j.1365-2265.1998.00564.x Occurrence Handle1:CAS:528:DyaK1cXnt1Gnu78%3D
WM Drake F Miraki A Siddigi et al. (1998) ArticleTitleDose-related effects of growth hormones on IGF-I and IGF-binding protein-3 levels in non-islet cell tumour hypoglycaemia Eur J Endocrinol 139 532–6 Occurrence Handle9849819 Occurrence Handle10.1530/eje.0.1390532 Occurrence Handle1:CAS:528:DyaK1cXnvFyhtbs%3D
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Zhou, P., Kudo, M., Chung, H. et al. Multiple metastases from a meningeal hemangiopericytoma associated with severe hypoglycemia. J Med Ultrasonics 32, 187–190 (2005). https://doi.org/10.1007/s10396-005-0049-8
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DOI: https://doi.org/10.1007/s10396-005-0049-8