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Corneal refractive error and astigmatism in patients aged 6 to 18 years with a history of retinopathy of prematurity and birth weight of <1500 g

  • Clinical Investigation
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Abstract

Purpose

To investigate corneal refractive power (CR) and astigmatism (AS) in 6- to 18-year-old children with a history of retinopathy of prematurity (ROP) and birth weight of <1500 g who either did or did not undergo retinal photocoagulation (PC).

Study design

Retrospective study.

Methods

We examined 143 eyes of 77 children in 2021. The children were divided into three groups for evaluation of CR and AS: those with a birth weight of ≥2500 g (normal birth weight [NBW] group, 13 eyes) as controls, those with spontaneously resolved ROP (sr-ROP group, 27 eyes), and those who underwent PC for treatment of ROP (PC-ROP group, 103 eyes). Swept-source anterior segment optical coherence tomography was used to analyze the cornea.

Results

The median CR in the NBW, sr-ROP, and PC-ROP groups was 42.2 (41.3, 42.8) diopters (D), 44.5 (43.2, 45.5) D, and 45.2 (43.8, 46.6) D, respectively. The median AS in the NBW, sr-ROP, and PC-ROP groups was 1.2 (1.0, 1.5) D, 1.1 (0.8, 1.6) D, and 2.1 (1.4, 2.7) D. In the PC-ROP group, the with-the-rule astigmatic axis was 97%. In all three groups, a strong positive correlation was found between the mean anterior and posterior CR (NBW: r=0.795, sr-ROP: r=0.842, PC-ROP: r=0.890) and AS (NBW: r=0.883, sr-ROP: r=0.841, PC-ROP: r=0.860).

Conclusion

CR was significantly higher in the sr-ROP (p=0.013) and PC-ROP (p<0.001) groups than in the NBW group. The PC-ROP group had significantly more AS than the sr-ROP group. There was a strong correlation between the anterior and posterior CR and AS.

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Acknowledgment

This research was funded by the Tokyo Metropolitan Government. We thank Angela Morben, DVM, ELS, from Edanz (https://jp.edanz.com/ac), for editing a draft of this manuscript.

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Authors and Affiliations

  1. Department of Ophthalmology, Tokyo Metropolitan Ohtsuka Hospital, Minami-Ohtsuka 2-8-1, Toshima-ku, Tokyo, 170-8476, Japan

    Takako Tachikawa, Ritsuko Ueno, Tetsuko Mita & Daisuke Yuzurihara

  2. Department of Ophthalmology, NHO Tokyo Medical Center, Tokyo, Japan

    Toru Noda

Authors
  1. Takako Tachikawa
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  2. Ritsuko Ueno
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  3. Tetsuko Mita
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  4. Daisuke Yuzurihara
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Corresponding author

Correspondence to Takako Tachikawa.

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Conflicts of interest

T. Tachikawa, None; R. Ueno, None; T. Mita, None; D. Yuzurihara, None; T. Noda, None.

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Corresponding Author: Takako Tachikawa

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Tachikawa, T., Ueno, R., Mita, T. et al. Corneal refractive error and astigmatism in patients aged 6 to 18 years with a history of retinopathy of prematurity and birth weight of <1500 g. Jpn J Ophthalmol 68, 42–49 (2024). https://doi.org/10.1007/s10384-023-01026-2

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  • DOI: https://doi.org/10.1007/s10384-023-01026-2

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