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The Outcome of Mitomycin C Trabeculectomy and Laser Suture Lysis Depends on Postoperative Management

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Abstract

Purpose

To verify that postoperative management affects the outcome of mitomycin C (MMC) trabeculectomy and suture lysis.

Methods

A total of 108 eyes in 108 Japanese patients were treated with MMC trabeculectomy. They were divided into two groups based on when the operation was performed: group A, 57 eyes in 1998, and group B, 51 eyes in 2001. The results, including postoperative intraocular pressure (IOP), complications, and postoperative management, were compared between groups. In addition, they were evaluated by a Kaplan-Meier life-table analysis.

Results

Postoperative IOP was lower and the probability of success by life-table analysis was higher in group B than in group A. Postoperative management, including laser suture lysis and subconjunctival injection of 5-fluorouracil, was started significantly earlier in group B than in group A patients. Although more postoperative complications occurred in group B, none were severe and all were adequately managed.

Conclusions

Starting postoperative management earlier, particularly laser suture lysis, may be necessary to achieve lower and longer IOP control in MMC trabeculectomy. Jpn J Ophthalmol 2006;50:455–459 © Japanese Ophthalmological Society 2006

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Authors and Affiliations

  1. Division of Ophthalmology and Visual Science, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan

    Takeo Fukuchi, Jun Ueda, Kiyoshi Yaoeda, Kieko Suda, Masaaki Seki & Haruki Abe

Authors
  1. Takeo Fukuchi
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  2. Jun Ueda
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  3. Kiyoshi Yaoeda
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  4. Kieko Suda
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  5. Masaaki Seki
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  6. Haruki Abe
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Correspondence to Takeo Fukuchi.

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Fukuchi, T., Ueda, J., Yaoeda, K. et al. The Outcome of Mitomycin C Trabeculectomy and Laser Suture Lysis Depends on Postoperative Management. Jpn J Ophthalmol 50, 455–459 (2006). https://doi.org/10.1007/s10384-006-0346-9

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  • DOI: https://doi.org/10.1007/s10384-006-0346-9

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