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Laparoscopic Liver Resection (LLR): state of the art

Laparoskopische Leberresektion (LLR): State of the Art

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Zusammenfassung

GRUNDLAGEN: Mit diesem Artikel wollen wir den derzeitigen Wissensstand bei laparoskopischen Leberresektionen (LLR) definieren. Sowohl die Rolle der Laparoskopie und des intraoperativen Ultraschalls für ein optimales Staging als auch deren Auswirkung auf die therapeutische Strategie werden dargestellt. Folgende Fragen können hiermit beantwortet werden: Welche Art von Tumoren und welche Patienten sind geeignet für eine LLR? Hiermit definieren wir die Indikationen und die onkologischen Einschränkungen. Wie können wir eine sichere LLR durchführen, welches sind die technischen Voraussetzungen, der Kostenvoranschlag und die Lernkurve? Hiermit definieren wir die Machbarkeit einer solchen Operation. Was sind die potentiellen Vorteile einer solchen Prozedur im Hinblick auf Konversion, Komplikationsraten und neuerliche Eingriffsrate in der Literatur? METHODIK: Review; um die Resultate auszuwerten, wurden nur Publikationen mit mehr als zehn LLR in Betracht bezogen. ERGEBNISSE: 17 Studien mit insgesamt 595 LLR wurden ausgewertet. Die Sterberate ist 0% und die Morbiditätsrate, dargestellt durch die Komplikationsrate, ist niedrig: 15,5% (4,7–45%). Die Konversionsrate beträgt 8,5% (54,5%). Bluttransfusionen kamen in 8,6% der Fälle vor und wiederholte Eingriffe in 1,06%. Die Resektionszone war in 0,79% von Tumorzellen befallen (0–7%), aber es konnten keine Metastasen in den Trokarteinschnitten festgestellt werden. SCHLUSSFOLGERUNGEN: Eine rezente Literaturübersicht bestätigt die Machbarkeit der LLR in 90%. Dies jedoch in ausgewählten Fällen, d. h. in kleinen Tumoren der vorderen Lebersegmente. Sie zeigt eine geringere Komplikationsrate, und dies bei gleichem Päroperativen Blutverlust. In malignen Tumoren ist eine Päroperative Ultraschallstudie von größter Wichtigkeit, um eine korrekte Resektionszone zu ereichen.

Summary

BACKGROUND: The purpose of this review is to define "state of the art" in laparoscopic liver resection (LLR), define the role of laparoscopy and intra-operative ultrasonography (IOUS) for optimization of the radiological diagnosis and its impact on indications, patient selection and improvement of procedure safety. Finally we aim to address economic and surgical technical issues, i.e. learning curve, conversion rate, and comparison to open technique. METHODS: Review on laparoscopic liver resection (LLR), we have only included studies reporting more than 10 liver resections. RESULTS: 17 series including 595 patients are considered. No deaths are reported and the morbidity indicated as mean of postoperative complications is low: 15.5% (range: 4.7–45). The mean conversion rate is 8.5% (range: 0–54.5%). The mean of patients transfused is 8.6% (range: 0–35%) and the reinterventions 1.06%. Surgical margins are invaded in 0.79% (range: 0–7%) but no port side metastases are observed. CONCLUSIONS: A review of literature confirms the feasibility of LLR in selected patients with small anterior tumours in 90%, a lesser morbidity rate even if perioperative blood loss is identical. A longer operative time is compensated by a shorter hospital stay. In malignant disease, IOUS and hand assisted laparoscopic surgery are of great importance to get adequate surgical margin.

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References

  • Azagra JS, Goergen M, Gilbart E, Jacobs D, Lejeune Ph, Carlier E (1995) Laparoscopic surgery for liver tumours. In: Kawasaki S, Makuuchi M (eds) Novel regional therapies for liver tumours. Heidelberg, Springer, pp 1:3–26

  • Barbot DJ, Marks JH, Feld RI, Liu JB, Rosato FE (1997) Improved staging of liver tumours using laparoscopic intraoperative ultrasound. J Surg Oncol 64: 63–67

    Article  PubMed  CAS  Google Scholar 

  • Catheline JM, Champault G (1999) Ultrasonographic laparoscopy of the liver. Chirurgie 124: 568–576

    Article  PubMed  CAS  Google Scholar 

  • Rahusen FD, Cuesta MA, Borgstein PJ, Bleichrodt RP, Barkhof F, Doesburg T et al (1999) Selection of patients for resection of colorectal metastases to the liver using diagnostic laparoscopy and laparoscopic ultrasonography. Ann Surg 230: 31–37

    Article  PubMed  CAS  Google Scholar 

  • Thaler K, Kanneganti S, Khajanchee Y, Wilson C, Swanstrom L, Hansen PD (2005) The evolving role of staging laparoscopy in the treatment of colorectal hepatic metastasis. Arch Surg 140: 727–734

    Article  PubMed  Google Scholar 

  • Belghiti J, Vilgrain V (1995) Liver resection for benign liver tumours: its indications and results. In: Kawasaki S, Makuuchi M (eds) Novel regional therapies for liver tumours. Heidelberg, Springer, pp 1:27–55

  • Cherqui D (2001) Benign liver tumors. J Chir (Paris) 138: 19–26

    CAS  Google Scholar 

  • Descottes B, Glineur D, Lachachi F, Valleix D, Paineau J, Hamy A, Morino M et al (2003) Laparoscopic liver resection of benign liver tumours. Surg Endosc 17: 23–30

    Article  PubMed  CAS  Google Scholar 

  • Gigot JF, Glineur D, Azagra JS, Goergen M, Ceuterick M, Morino M, Etienne J et al (2002) Laparoscopic liver resection for malignant liver tumors: preliminary results of a multicenter European study. Ann Surg 236: 90–97

    Article  PubMed  Google Scholar 

  • Cherqui D, Soubrane O, Husson E, Barshsz E, Vignaux O, Ghimouz M et al (2002) Laparoscopic living donor hepatectomy for liver transplantation in children. Lancet 359: 368–370

    Article  Google Scholar 

  • Gagner M, Rheault M, Dubuc J (1992) Laparoscopic partial hepatectomy for liver tumour. Surg Endosc 6: 99

    Google Scholar 

  • Azagra JS, Goergen M, Jacobs D (1994) Laparoscopic left lateral segmentectomy (left hepatic lobectomy). Endosurgery 1: 7–9

    Google Scholar 

  • Azagra JS, Goergen M, Gilbart E, Jacobs D (1996) Laparoscopic anatomical (hepatic) left lateral segmentectomy: technical aspects. Surg Endosc 10: 758–761

    Article  PubMed  CAS  Google Scholar 

  • Huscher CG, Lirici MM, Chiodini S (1998) Laparoscopic liver resections. Semin Laparosc Surg 5: 204–210

    PubMed  CAS  Google Scholar 

  • Cherqui D, Husson E, Hammoud R, Malassagne B, Stephan F, Bensaid S et al (2000) Laparoscopic liver resections: a feasibility study in 30 patients. Ann Surg 232: 753–762

    Article  PubMed  CAS  Google Scholar 

  • O'Rourke N, Fielding G (2004) Laparoscopic right hepatectomy: surgical technique. J Gastrointest Surg 8: 213–216

    Article  PubMed  Google Scholar 

  • Sakamoto Y, Yamamoto J, Kokudo N, Seki M, Kosuge T, Yamaguchi T, Muto T, Makuuchi M (2004) Bloodless liver resections using the monopolar floating ball plus ligasure diathermy: preliminary results of 16 liver resections. World J Surg 28: 166–172

    Article  PubMed  Google Scholar 

  • Haghighi K, Wang F, King J, Daniel S, Morris DL (2005) In-line radiofrequency ablation to minimize blood loss in hepatic parenchymal transaction. Am J Surg 190: 43–47

    Article  PubMed  Google Scholar 

  • Cushieri A (2001) Laparoscopic hand-assisted hepatic surgery. Semin Laparosc Surg 8: 104–113

    Article  Google Scholar 

  • Fong Y, Jarnagin W, Conlon KC, Dematteo R, Dougherty E, Blumgart LH (2000) Hand-assisted laparoscopic liver resection. Lessons from an initial experience. Arch Surg 135: 854–859

    Article  PubMed  CAS  Google Scholar 

  • Biertho L, Waage A, Gagner M (2002) Laparoscopic hepatectomy. Ann Chir 127: 164–170

    Article  PubMed  CAS  Google Scholar 

  • Schamandra TC, Mierdl S, Bauer H, Gutt C, Hanisch E (2002) Transoesophageal echocardiography shows high of gas embolism during laparoscopic hepatic resection under carbon dioxide pneumoperitoneum. Br J Surg 89: 870–876

    Article  Google Scholar 

  • Schamandra TC, Mierdl S, Hollander D, Hanisch E, Gutt C (2004) Risk of gas embolism in hand-assisted versus total laparoscopic hepatic resection. Surg Technol Int 12: 137–143

    Google Scholar 

  • Consten EC, Gagner M (2005) Per-operative outcome of laparoscopic left lateral liver resection is improved by using staple line reinforcement technique: a case report. J Gastrointest Surg 9: 360–364

    Article  PubMed  Google Scholar 

  • Rau HG, Buttler E, Meyer G, Schardey HM, Schildberg FW (1998) Laparoscopic liver resection compared with conventional partial hepatectomy – a prospective analysis. Hepatogastroenterology 45: 2333–2338

    PubMed  CAS  Google Scholar 

  • Shimada M, Hashizume M, Marhara S, Tsujita E, Rikimaru T, Yamashita Y et al (2001) Laparoscopic hepatectomy for hepatocellular carcinoma. Surg Endosc 15: 541–544

    Article  PubMed  CAS  Google Scholar 

  • Farges O, Jagot P, Kirstetter P, Marty J, Belghiti J (2002) Prospective assessment of the safety and benefit of laparoscopic liver resections. J Hepatobiliary Pancreat Surg 9: 242–219

    Article  PubMed  Google Scholar 

  • Mala T, Edwin B, Gladhaug I et al (2002) A comparative study of the short term outcome following open and laparoscopic liver resection of colorectal metastasis. Surg Endosc 16: 1059–1063

    Article  PubMed  CAS  Google Scholar 

  • Lessurtel M, Cherqui D, Laurent A, Tayar C, Fagniez PL (2003) Laparoscopic vs. open left lateral hepatic lobectomy: a case-control study. J Am Coll Surg 196: 236–238

    Article  Google Scholar 

  • Morino M, Morra I, Rosso E, Miglietta C, Garrone C (2003) Laparoscopic vs. open hepatic resection: a comparative study. Surg Endosc 17: 1914–1918

    Article  PubMed  CAS  Google Scholar 

  • O'Rourke N, Shaw I, Nathanson L, Martin I, Fielding G (2004) Laparoscopic resection of hepatic colorectal metastases. HPB 4: 230–235

    Google Scholar 

  • Buell JF, Thomas MJ, Doty TC, Gersin KS, Merchen T, Gupta M, Rudich S, Woodle ES (2004) An initial experience and evolution of laparoscopic hepatic resectional surgery. Surgery 136: 804–811

    Article  PubMed  Google Scholar 

  • Belli G, Fantini C, D'Agostino A, Belli A, Russolillo N, Cioffi L (2005) Laparoscopic liver resection without a Pringle manoeuvre for HCC in cirrhotic patients. Chir Ital 57: 15–25

    PubMed  Google Scholar 

  • Teramoto K, Kawamura T, Takamatsu S, Nakamura N, Kudo A, Noguchi N, Irie T, Ari S (2005) Laparoscopic and thoracoscopic approaches for the treatment of hepatocellular carcinoma. Am J Surg 189: 474–478

    Article  PubMed  Google Scholar 

  • Dulucq JL, Wintringer P, Stabillini C, Berticelli J, Mahajna A (2005) Laparoscopic liver resections: a single centre experience. Surg Endosc 19: 886–891

    Article  PubMed  CAS  Google Scholar 

  • Vibert E, Perniceni T, Levard H, Denet C, Shahri NK, Gayet B (2006) Laparoscopic liver resection. Br J Surg 93: 67–72

    Article  PubMed  CAS  Google Scholar 

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Correspondence to J. S. Azagra.

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Azagra, J., Goergen, M., Gigot, J. et al. Laparoscopic Liver Resection (LLR): state of the art. Eur Surg 38, 378–383 (2006). https://doi.org/10.1007/s10353-006-0289-x

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  • DOI: https://doi.org/10.1007/s10353-006-0289-x

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