Purpose
We compared overall survival and disease-free survival in colorectal cancer patients with and without invasion of urinary organs.
Methods
We clarified the potential predictors of the overall and disease-free survivals after surgery, the factors associated with direct tumor invasion of the urinary organs, postoperative complications, recurrence sites, and survival in patients with and without urinary organ resection in 171 patients with Stage III colorectal cancer who underwent surgery, including 23 patients with tumor invasion of the urinary organs and 148 patients without invasion.
Results
Old age (65 years or older), rectal cancer, and macroscopic Type 3 and 4 disease were found to be independent poor prognostic factors for the overall and disease-free survivals in all patients. The overall and disease-free survivals in patients with direct tumor invasion of the urinary organs were not shorter than those in patients without invasion. A large extent of tumors located in the cross-sectional circumference of the bowel (≥72 percent) and a large maximum tumor size (>50 mm) were significant tumor characteristics associated with positive direct tumor invasion of the urinary organs by sigmoid and rectal cancers. Although the local recurrence of patients with tumor invasion of the urinary organs occurred more frequently in patients without invasion, there were no differences in the overall and disease-free survivals between the patients without a urinary organ resection and those with a local resection of urinary bladder or ureter.
Conclusions
The survival of patients with a urinary invasion was not shorter than that of patients without urinary invasion.
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References
TE Voyer ParticleLe ER Sigurdson AL Hanlon et al. (2003) ArticleTitleColon cancer survival is associated with increasing number of lymph nodes analyzed: a secondary survey of intergroup trial INT-0089 J Clin Oncol 21 2912–2919 Occurrence Handle12885809 Occurrence Handle10.1200/JCO.2003.05.062
S Ohwada S Kawate T Ikeya et al. (2003) ArticleTitleAdjuvant therapy with protein-bound polysaccharide K and tegafur uracil in patients with stage II or III colorectal cancer: randomized, controlled trial Dis Colon Rectum 46 1060–1068 Occurrence Handle12907900 Occurrence Handle10.1007/s10350-004-7281-y
DK Dhar H Yoshimura N Kinukawa et al. (2005) ArticleTitleMetastatic lymph node size and colorectal cancer prognosis J Am Coll Surg 200 20–28 Occurrence Handle15631916 Occurrence Handle10.1016/j.jamcollsurg.2004.09.037
J Walker P Quirke (2002) ArticleTitlePrognosis and response to therapy in colorectal cancer Eur J Cancer 38 880–886 Occurrence Handle11978512 Occurrence Handle1:STN:280:DC%2BD383ktVyrtg%3D%3D Occurrence Handle10.1016/S0959-8049(02)00044-8
DA McNamara JM Fitzpatrick PR O’Connell (2003) ArticleTitleUrinary tract involvement by colorectal cancer Dis Colon Rectum 46 1266–1276 Occurrence Handle12972973 Occurrence Handle10.1007/s10350-004-6725-8
M Fujisawa T Nakamura M Ohno et al. (2002) ArticleTitleSurgical management of the urinary tract in patients with locally advanced colorectal cancer Urology 60 983–987 Occurrence Handle12475654 Occurrence Handle10.1016/S0090-4295(02)01987-8
T Kobayashi T Kamoto Y Sugino et al. (2003) ArticleTitleHigh incidence of urinary bladder involvement in carcinomas of the sigmoid and rectum: a retrospective review of 580 patients with colorectal carcinoma J Surg Oncol 84 209–214 Occurrence Handle14756431 Occurrence Handle10.1002/jso.10322
J Olędzki M Chwaliński W Rogowski et al. (2004) ArticleTitleTotal cystectomies in the surgical treatment of rectal cancer with prior chemoradiation: analysis of postoperative morbidity and survival Int J Colorectal Dis 19 124–127 Occurrence Handle14557892 Occurrence Handle10.1007/s00384-003-0550-8
C Gebhardt W Meyer S Ruckriegel et al. (1999) ArticleTitleMultivisceral resection of advanced colorectal carcinoma Langenbecks Arch Surg 384 194–199 Occurrence Handle10328174 Occurrence Handle1:STN:280:DyaK1M3lvVOhtA%3D%3D Occurrence Handle10.1007/s004230050191
P Russo B Ravindran J Katz et al. (1999) ArticleTitleUrinary diversion after total pelvic exenteration for rectal cancer Ann Surg Oncol 6 732–738 Occurrence Handle10622500 Occurrence Handle1:STN:280:DC%2BD3c%2Fos1aisA%3D%3D Occurrence Handle10.1007/s10434-999-0732-x
MD Balbay JW Slaton N Trane et al. (1999) ArticleTitleRationale for bladder-sparing surgery in patients with locally advanced colorectal carcinoma Cancer 86 2212–2216 Occurrence Handle10590359 Occurrence Handle1:STN:280:DC%2BD3c%2FlvFGksA%3D%3D Occurrence Handle10.1002/(SICI)1097-0142(19991201)86:11<2212::AID-CNCR6>3.0.CO;2-2
PW Carne JN Frye A Kennedy-Smith et al. (2004) ArticleTitleLocal invasion of the bladder with colorectal cancers: surgical management and patterns of local recurrence Dis Colon Rectum 47 44–47 Occurrence Handle14719150 Occurrence Handle1:STN:280:DC%2BD2c%2FitV2iuw%3D%3D Occurrence Handle10.1007/s10350-003-0011-z
WL Law KW Chu HK Choi (2000) ArticleTitleTotal pelvic exenteration for locally advanced rectal cancer J Am Coll Surg 190 78–83 Occurrence Handle10625236 Occurrence Handle1:STN:280:DC%2BD3c%2FovVGktg%3D%3D Occurrence Handle10.1016/S1072-7515(99)00229-X
InstitutionalAuthorNameUICC (1997) TNM classification of malignant tumors EditionNumber4 Springer-Verlag New York
MS Talamonti CR Shumate GW Carlson et al. (1993) ArticleTitleLocally advanced carcinoma of the colon and rectum involving the urinary bladder Surg Gynecol Obstet 177 481–487 Occurrence Handle8211600 Occurrence Handle1:STN:280:ByuD38vks1I%3D
SA Curley GW Carlson CR Shumate et al. (1992) ArticleTitle Extended resection for locally advanced colorectal carcinoma Am J Surg 163 553–559 Occurrence Handle1595834 Occurrence Handle1:STN:280:By2B1c%2FpvVI%3D Occurrence Handle10.1016/0002-9610(92)90554-5
RG Beets-Tan GL Beets RF Vliegen et al. (2001) ArticleTitleAccuracy of magnetic resonance imaging in prediction of tumour-free resection margin in rectal cancer surgery Lancet 357 497–504 Occurrence Handle11229667 Occurrence Handle1:STN:280:DC%2BD3M7lt1Shtg%3D%3D Occurrence Handle10.1016/S0140-6736(00)04040-X
IP Bissett CC Fernando DM Hough et al. (2001) ArticleTitleIdentification of the fascia propria by magnetic resonance imaging and its relevance to preoperative assessment of rectal cancer Dis Colon Rectum 44 259–265 Occurrence Handle11227944 Occurrence Handle1:STN:280:DC%2BD3M7ot1SktA%3D%3D Occurrence Handle10.1007/BF02234302
MP Vezeridis NJ Petrelli A Mittelman (1987) ArticleTitleThe value of routine preoperative urologic evaluation in patients with colorectal carcinoma Dis Colon Rectum 30 758–760 Occurrence Handle3652888 Occurrence Handle1:STN:280:BieD3czpt1c%3D
NC Gupta PM Falk AL Frank et al. (1993) ArticleTitlePre-operative staging of colorectal carcinoma using positron emission tomography Nebr Med J 78 30–35 Occurrence Handle8441482 Occurrence Handle1:STN:280:ByyC1c%2Fpt1M%3D
MJ Lopez WW Monafo (1993) ArticleTitleRole of extended resection in the initial treatment of locally advanced colorectal carcinoma Surgery 113 365–372 Occurrence Handle7681222 Occurrence Handle1:STN:280:ByyB3cnit1A%3D
M Poeze JG Houbiers CJ Velde Particlevan de et al. (1995) ArticleTitleRadical resection of locally advanced colorectal cancer Br J Surg 82 1386–1390 Occurrence Handle7489174 Occurrence Handle1:STN:280:BymD1MjotlA%3D
T Lehnert M Methner A Pollok et al. (2002) ArticleTitleMultivisceral resection for locally advanced primary colon and rectal cancer Ann Surg 235 217–225 Occurrence Handle11807361 Occurrence Handle10.1097/00000658-200202000-00009
JR Izbicki SB Hosch WT Knoefel et al. (1995) ArticleTitleExtended resections are beneficial for patients with locally advanced colorectal cancer Dis Colon Rectum 38 1251–1256 Occurrence Handle7497835 Occurrence Handle1:STN:280:BymC3c7lsFc%3D Occurrence Handle10.1007/BF02049148
S Yamamoto N Yamanaka T Maeda et al. (2001) ArticleTitleIleal neobladder for urinary bladder replacement following total pelvic exenteration for rectal carcinoma Dig Surg 18 67–72 Occurrence Handle11244263 Occurrence Handle1:STN:280:DC%2BD3M3os1emtQ%3D%3D Occurrence Handle10.1159/000050100
BA Orkin RR Dozois RW Beart et al. (1989) ArticleTitleExtended resection for locally advanced primary adenocarcinoma of the rectum Dis Colon Rectum 32 286–292 Occurrence Handle2924669 Occurrence Handle1:STN:280:BiaC2s%2FgsFY%3D
JA Hunter JA Ryan SuffixJr P Schultz (1987) ArticleTitleEn bloc resection of colon cancer adherent to other organs Am J Surg 154 67–71 Occurrence Handle2440334 Occurrence Handle1:STN:280:BiiB28fjtl0%3D Occurrence Handle10.1016/0002-9610(87)90292-3
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Hotta, T., Takifuji, K., Yokoyama, S. et al. Survival in Colorectal Cancer Patients With Urinary Tract Invasion. Dis Colon Rectum 49, 1399–1409 (2006). https://doi.org/10.1007/s10350-006-0607-1
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DOI: https://doi.org/10.1007/s10350-006-0607-1