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The Development and Validation of a Liquid Chromatography–Tandem Mass Spectrometry Procedure for the Determination of Dioctyldiethylenetriamine Acetate Residues in Soil, Green and Cured Tobacco Leaves Using a Modified QuEChERS Approach

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Abstract

A liquid chromatography with electrospray ionization tandem mass spectrometry method was developed and validated for the determination of dioctyldiethylenetriamine acetate in soil and tobacco. The separation was performed on a Restek Ultra AQ C18 column (2.1 × 100 mm i.d., particle size 3 µm) at 40 °C with a gradient elution. Methanol and trifluoroacetic acid (0.1%) were used as mobile phase, and the flow rate was set at 0.3 mL min−1. A modified quick, easy, cheap, effective, rugged, and safe (QuEChERS) method was used for sample extraction and cleanup pretreatment. The recovery was tested in the real samples and calculated to be 86.3–97.4%, the relative standard deviations were 1.1–11.9%. The limits of detection and quantitation were 3.3–16.7 and 10–50 µg kg−1, respectively. The method was demonstrated to be reliable for the routine monitoring of dioctyldiethylenetriamine acetate in tobacco samples.

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Funding

This study was funded by the National Key Research and Development Program of China (Grant number 2016YFD0200203-3).

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  1. Jin Gong and Guoqiang Yang have contributed equally to the manuscript.

Authors and Affiliations

  1. State Key Laboratory Breeding Base of Green Pesticide and Agricultural Bioengineering, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Guizhou University, Guiyang, 550025, People’s Republic of China

    Jin Gong, Guoqiang Yang, Weiwei Yu, Min Huang, Fuqin Li, Mingjiao Jin, Deyu Hu & Kankan Zhang

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  1. Jin Gong
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  3. Weiwei Yu
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  7. Deyu Hu
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Correspondence to Deyu Hu or Kankan Zhang.

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Conflict of interest

Jin Gong declares that he has no conflicts of interest. Guoqiang Yang declares that he has no conflicts of interest. Weiwei Yu declares that she has no conflicts of interest. Min Huang declares that she has no conflicts of interest. Fuqin Li declares that she has no conflicts of interest. Mingjiao Jin declares that she has no conflicts of interest. Deyu Hu declares that she has no conflicts of interest. Kankan Zhang declares that he has no conflicts of interest.

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Gong, J., Yang, G., Yu, W. et al. The Development and Validation of a Liquid Chromatography–Tandem Mass Spectrometry Procedure for the Determination of Dioctyldiethylenetriamine Acetate Residues in Soil, Green and Cured Tobacco Leaves Using a Modified QuEChERS Approach. Chromatographia 81, 1035–1041 (2018). https://doi.org/10.1007/s10337-018-3535-z

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  • DOI: https://doi.org/10.1007/s10337-018-3535-z

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