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3D diffusion tensor imaging with 2D navigated turbo spin echo

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Abstract

A Cartesian two-dimensional navigator with variable orientation for online motion correction is introduced. It corrects for all possible zeroth- and first-order phase errors due to rigid-body motion of a subject during the diffusion-weighting preparation. The technique is developed for the application of three-dimensional (3D) imaging sequences, which offer the opportunity of high-resolution diffusion-weighted imaging, or diffusion tensor imaging (DTI) with isotropic voxel resolution. The navigator was applied to a displaced 3D turbo spin-echo sequence with an ECG-gated diffusion preparation to avoid phase errors due to gross brain pulsation. Online and offline corrected in vivo images acquired with this sequence are compared to investigate the advantages of online correction. Also eigenvector maps of the diffusion tensor are presented with an isotropic resolution of 1 mm3, which indicate that this new navigator technique is a promising approach for high-resolution DTI.

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References

  1. Arfanakis K, Hermann BP, Rogers BP, Carew JD, Seidenberg M, Meyerand ME (2002) Diffusion tensor MRI in temporal lobe epilepsy. Magn Reson Imaging 20(7):511–519

    Article  PubMed  Google Scholar 

  2. Moseley M (2002) Diffusion tensor imaging and aging–-a review. NMR Biomed 15(7–8):553–560

    Google Scholar 

  3. Assaf Y, Ben-Bashat D, Chapman J, Peled S, Biton IE, Kafri M, Segev Y, Hendler T, Korczyn AD, Graif M, Cohen Y (2002) High b-value q-space analyzed diffusion-weighted MRI: application to multiple sclerosis. Magn Reson Med 47(1):115–126

    Article  PubMed  Google Scholar 

  4. Sotak CH (2002) The role of diffusion tensor imaging in the evaluation of ischemic brain injury—a review. NMR Biomed 15(7–8):561–569

    Google Scholar 

  5. Le Bihan D, Mangin JF, Poupon C, Clark CA, Pappata S, Molko N, Chabriat H (2001) Diffusion tensor imaging: concepts and applications. J Magn Reson Imaging 13(4):534–546

    Article  PubMed  Google Scholar 

  6. Foong J, Symms MR, Barker GJ, Maier M, Miller DH, Ron MA (2002) Investigating regional white matter in schizophrenia using diffusion tensor imaging. NeuroReport 13(3):333–336

    Article  PubMed  Google Scholar 

  7. Anderson AW, Gore JC (1994) Analysis and correction of motion artifacts in diffusion-weighted imaging. Magn Reson Med 32(3):379–387

    PubMed  Google Scholar 

  8. Greitz D, Wirestam R, Franck A, Nordell B, Thomsen C, and Stahlberg F (1992) Pulsatile brain movement and associated hydrodynamics studied by magnetic resonance phase imaging. The Monro-Kellie doctrine revisited. Neuroradiology 34(5):370–380

    Article  PubMed  Google Scholar 

  9. Golay X, Jiang H, van Zijl PCM, Mori S (2002) High-resolution isotropic 3D diffusion tensor imaging of the human brain. Magn Reson Med 47(5): 837–843

    Article  PubMed  Google Scholar 

  10. Jeong EK, Kim SE, Parker DL (2003) High-resolution diffusion-weighted 3D MRI, using diffusion-weighted driven-equilibrium (DW-DE) and multishot segmented 3D-SSFP without navigator echoes. Magn Reson Med 50(4):821–829

    Article  PubMed  Google Scholar 

  11. Bosak E, Harvey PR (2001) Navigator motion correction of diffusion-weighted 3D SSFP imaging. Magn Reson Mater Phys Biol Med 12(2–3):167–176

    Google Scholar 

  12. Butts K, Pauly JM, de~Crespigny A, Moseley M (1997) Isotropic diffusion-weighted and spiral-navigated interleaved EPI for routine imaging of acute stroke. Magn Reson Med 38(5):741–749

    PubMed  Google Scholar 

  13. Miller KL, Hargreaves BA, Gold GE Pauly JM (2004) Steady-state diffusion-weighted imaging of in vivo knee cartilage. Magn Reson Med 51(2):394–398

    Article  PubMed  Google Scholar 

  14. Atkinson D, Porter DA, Hill DL, Calamante F, Connelly A (2000) Sampling and reconstruction effects due to motion in diffusion-weighted interleaved echo planar imaging. Magn Reson Med 44(1):101–109

    Article  PubMed  Google Scholar 

  15. Norris DG, Driesel W (2001) Online motion correction for diffusion-weighted imaging using navigator echoes: application to RARE imaging without sensitivity loss. Magn Reson Med 45(5):729–733

    Article  PubMed  Google Scholar 

  16. Norris DG, Bornert P, Reese T, Leibfritz D (1992) On the application of ultra-fast RARE experiments. Magn Reson Med 27(1):142–164

    PubMed  Google Scholar 

  17. Reese TG, Heid O, Weisskoff RM, Wedeen VJ (2003) Reduction of eddy-current-induced distortion in diffusion MRI using a twice-refocused spin echo. Magn Reson Med 49(1):177–182

    Article  PubMed  Google Scholar 

  18. Lee JH, Garwood M, Menon R, Adriany G, Andersen P, Truwit CL, Ugurbil K (1995) High contrast and fast three-dimensional magnetic resonance imaging at high fields. Magn Reson Med 34(3):308–312

    PubMed  Google Scholar 

  19. Hasan KM, Basser PJ, Parker DL, Alexander AL (2001) Analytical computation of the eigenvalues and eigenvectors in DT-MRI. J Magn Reson 152(1):41–47

    Article  PubMed  Google Scholar 

  20. Sener RN (2001) Diffusion MRI: apparent diffusion coefficient (ADC) values in the normal brain and a classification of brain disorders based on ADC values. Comput Med Imaging Graph 25(4):299–326

    Article  PubMed  Google Scholar 

  21. Press WH, Teukolsky SA, Vetterling WT, Flannery BP (1994) Numerical Recipes in C. Cambridge University Press, London, pp. 670–675

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Correspondence to M. von Mengershausen.

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von Mengershausen, M., Norris, D. & Driesel, W. 3D diffusion tensor imaging with 2D navigated turbo spin echo. MAGMA 18, 206–216 (2005). https://doi.org/10.1007/s10334-005-0118-4

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  • DOI: https://doi.org/10.1007/s10334-005-0118-4

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