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Prevalence of joint replacement surgery in rheumatoid arthritis patients: cross-sectional analysis in a large observational cohort in Japan

  • Original Article
  • Published:
Modern Rheumatology

Abstract

The purpose of this study was to describe the prevalence of total joint arthroplasty (TJA) in Japanese rheumatoid arthritis (RA) patients undergoing conventional drug treatment in a large observational cohort in Japan. A total of 5,177 RA patients were studied for the prevalence of TJA, who were enrolled in the NinJa database during the fiscal year of 2006. The cases of 2,695 RA patients with more than ten years of disease duration were extracted and subjected to further analysis. The prevalence of TJA increased in accordance with the disease duration, and the prevalence was markedly increased after ten years. Among the 2,695 patients with more than ten years of disease duration, 1,431 TJAs were performed in 645 (24.6%) patients. The patients with TJA had higher disease activity than those without TJA. In this cross-sectional study, TJAs were performed in approximately a quarter of the Japanese RA patients with more than ten years of disease duration. The result showed that patients with higher disease activity required TJA.

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Acknowledgments

The authors thank Takako Nishino and Mayumi Yokoyama, who provided expert technical assistance. The authors wish to acknowledge the assistance of the following clinicians who have referred patients to NinJa 2006: Dr. Kenji Ichikawa, Dr. Masaki Fujita, Dr. Norio Tamura, Dr. Makoto Sueishi, Dr. Yoshiaki Kuga, Dr. Kumiko Akiya, Dr. Hajime Yamagata, Dr. Hiroshi Tsutani, Dr. Kunikazu Ogawa, Dr. Hidetoshi Yanagida, Dr. Akira Okamoto, Dr. Yusuke Ohta, Dr. Akinori Matsumori, Dr. Kazuhito Shinohara, Dr. Takeharu Tonai, Dr. Eiichi Suematsu, Dr. Shigeru Yoshizawa, Dr. Satoru Motokawa, Dr. Yojiro Kawabe, Dr. Yoshiki Shiohira and Dr. Issaku Toyohara. This work was supported in part by Health Science research grants from the Ministry of Health, Labor, and Welfare of Japan to Shigeto Tohma. Pacific Edit reviewed the manuscript prior to submission.

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Authors and Affiliations

  1. Nishino Clinic Orthopedics and Rheumatology, 2-9-15 Nishigaoka, Kita-ku, Tokyo, 115-0056, Japan

    Jinju Nishino

  2. Department of Orthopaedic Surgery, Faculty of Medicine, The University of Tokyo, Tokyo, Japan

    Sakae Tanaka

  3. Department of Rheumatology, Sagamihara National Hospital, National Hospital Organization (NHO), Kanagawa, Japan

    Toshihiro Matsui

  4. Department of Orthopaedic Surgery, Sagamihara National Hospital, National Hospital Organization (NHO), Kanagawa, Japan

    Toshihito Mori

  5. Department of Orthopaedic Surgery, Teikyo University School of Medicine, Tokyo, Japan

    Keita Nishimura

  6. Department of Orthopedics, Nagoya Medical Center, NHO, Nagoya, Japan

    Yoshito Eto & Atsushi Kaneko

  7. Department of Rheumatology, Miyakonojo Hospital, NHO, Miyazaki, Japan

    Koichiro Saisho

  8. Department of Rheumatology, Beppu Medical Center, NHO, Oita, Japan

    Masayuki Yasuda

  9. Department of Rheumatology, Morioka National Hospital, NHO, Iwate, Japan

    Noriyuki Chiba

  10. Rheumatic Disease Center, Kurashiki Medical Center, Kurashiki, Japan

    Yasuhiko Yoshinaga

  11. Department of Rheumatology and Clinical Research, NHO National Osaka Minami Medical Center, Osaka, Japan

    Yukihiko Saeki

  12. Division of Orthopedics, National Center for Child Medical Health and Development, Tokyo, Japan

    Atsuhito Seki

  13. Department of Rheumatology, Clinical Research Center for Allergy and Rheumatology, Sagamihara Hospital, NHO, Kanagawa, Japan

    Shigeto Tohma

Authors
  1. Jinju Nishino
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  2. Sakae Tanaka
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  3. Toshihiro Matsui
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  6. Yoshito Eto
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  7. Atsushi Kaneko
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  8. Koichiro Saisho
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  9. Masayuki Yasuda
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  10. Noriyuki Chiba
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  11. Yasuhiko Yoshinaga
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  12. Yukihiko Saeki
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  13. Atsuhito Seki
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  14. Shigeto Tohma
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Corresponding author

Correspondence to Jinju Nishino.

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Nishino, J., Tanaka, S., Matsui, T. et al. Prevalence of joint replacement surgery in rheumatoid arthritis patients: cross-sectional analysis in a large observational cohort in Japan. Mod Rheumatol 19, 260–264 (2009). https://doi.org/10.1007/s10165-009-0163-3

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  • DOI: https://doi.org/10.1007/s10165-009-0163-3

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