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Molecular and genetic insights into secondary metabolic regulation underlying insect-pest resistance in legumes

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A Correction to this article was published on 06 July 2023

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Abstract

Insect pests pose a major threat to agricultural production, resulting in significant economic losses for countries. A high infestation of insects in any given area can severely reduce crop yield and quality. This review examines the existing resources for managing insect pests and highlights alternative eco-friendly techniques to enhance insect pest resistance in legumes. Recently, the application of plant secondary metabolites has gained popularity in controlling insect attacks. Plant secondary metabolites encompass a wide range of compounds such as alkaloids, flavonoids, and terpenoids, which are often synthesized through intricate biosynthetic pathways. Classical methods of metabolic engineering involve manipulating key enzymes and regulatory genes to enhance or redirect the production of secondary metabolites in plants. Additionally, the role of genetic approaches, such as quantitative trait loci mapping, genome-wide association (GWAS) mapping, and metabolome-based GWAS in insect pest management is discussed, also, the role of precision breeding, such as genome editing technologies and RNA interference for identifying pest resistance and manipulating the genome to develop insect-resistant cultivars are explored, highlighting the positive contribution of plant secondary metabolites engineering-based resistance against insect pests. It is suggested that by understanding the genes responsible for beneficial metabolite compositions, future research might hold immense potential to shed more light on the molecular regulation of secondary metabolite biosynthesis, leading to advancements in insect-resistant traits in crop plants. In the future, the utilization of metabolic engineering and biotechnological methods may serve as an alternative means of producing biologically active, economically valuable, and medically significant compounds found in plant secondary metabolites, thereby addressing the challenge of limited availability.

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The data used during the current study are available from the corresponding author upon reasonable request.

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Author notes

  1. Muhammad Khuram Razzaq and Aiman Hina contributed equally to this work.

Authors and Affiliations

  1. Soybean Research Institute & MARA National Centre for Soybean Improvement & MARA Key Laboratory of Biology and Genetic Improvement of Soybean & National Key Laboratory for Crop Genetics and Germplasm Enhancement & Jiangsu Collaborative Innovation Centre for Modern Crop Production, Nanjing Agricultural University, Nanjing, 210095, China

    Muhammad Khuram Razzaq & Guangnan Xing

  2. Ministry of Agriculture (MOA) National Centre for Soybean Improvement, State Key Laboratory for Crop Genetics and Germplasm Enhancement, Nanjing Agricultural University, Nanjing, 210095, China

    Aiman Hina

  3. Department of Environmental Sciences, Kohsar University Murree, Murree, 47150, Pakistan

    Asim Abbasi & Sumaira Maqsood

  4. Department of Agricultural Biotechnology, Faculty of Agriculture, Food and Consumer Sciences, University for Development Studies, Tamale, Ghana

    Benjamin Karikari

  5. State Key Laboratory of Ecological Pest Control for Fujian and Taiwan crops, College of Plant Protection, Fujian Agriculture and Forestry University, Fuzhou, 350002, China

    Hafiza Javaria Ashraf

  6. Environmental Management Consultants (EMC) Private Limited, Islamabad, 44000, Pakistan

    Muhammad Mohiuddin

  7. Department of Zoology, University of Central Punjab, Bahawalpur, 63100, Pakistan

    Aqsa Maqsood

  8. College of Plant Protection, Gansu Agricultural University, Lanzhou, No. 1 Yingmen Village, Anning District, Lanzhou, 730070, China

    Inzamam Ul Haq

  9. National Institute for Biotechnology and Genetic Engineering Faisalabad, Faisalabad, Pakistan

    Ghulam Raza

  10. International Genome Center, Jiangsu University, Zhenjiang, 212013, China

    Javaid Akhter Bhat

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  1. Muhammad Khuram Razzaq
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  2. Aiman Hina
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  8. Aqsa Maqsood
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  9. Inzamam Ul Haq
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  12. Javaid Akhter Bhat
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M.K.R. and A.H. conceived and designed the project. A.H., M.K.R., A.A., M.M., H.J.A., I.U.H., and S.M. contributed to writing the original draft, data verification, and proofreading. A.H., A.A., A.M., B.K., J.A.B., G.R., and G.X. revised the paper. All authors have read and agreed to the final version of the manuscript.

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Correspondence to Muhammad Khuram Razzaq or Aiman Hina.

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The original online version of this article was revised: The original version of this article contains an error. The author name “Muhammad Khurum Razzaq” should be corrected to “Muhammad Khuram Razzaq”.

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Razzaq, M.K., Hina, A., Abbasi, A. et al. Molecular and genetic insights into secondary metabolic regulation underlying insect-pest resistance in legumes. Funct Integr Genomics 23, 217 (2023). https://doi.org/10.1007/s10142-023-01141-w

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  • DOI: https://doi.org/10.1007/s10142-023-01141-w

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