Abstract
Elderly adults are at increased risk for complications related to both delayed diagnosis of appendicitis and to unnecessary appendectomy. We assessed the diagnostic performance of computed tomography (CT) in a consecutive elderly cohort with clinically suspected appendicitis. CT findings and clinical outcomes were analyzed for 262 consecutive adult patients age 65 and older (mean 75.6 ± 7.5 years; range 65–94; M/F 111:151) referred for clinically suspected appendicitis at a single medical center between January 2000 and December 2009. The overall prevalence of proven acute appendicitis in this elderly cohort with clinically suspected appendicitis was 16.8% (44/262). CT sensitivity, specificity, PPV, and NPV for acute appendicitis were 100% (44/44), 99.1% (216/218), 95.7% (44/46), and 100.0% (216/216), respectively. The negative appendectomy rate was 2.3% (1/43). The perforation rate was 40.9% (18/44). There were no false-negative and two false-positive CT interpretations. All patients with appendicitis suspected on CT were hospitalized (44/44), with an average stay of 5.7 ± 3.2 days, and 93.5% (43/46) underwent appendectomy. Overall surgical complication rate was 34.9% (15/43). Compared with younger adults over the same period, elderly patients had higher rates of perforation and surgical complications, and longer hospital stays (p < 0.003). CT is highly accurate for the evaluation of clinically suspected appendicitis in elderly patients. Prompt diagnosis is important given the higher rates perforation and surgical complications relative to younger adults.
Similar content being viewed by others
References
Addiss DG, Shaffer N, Fowler BS et al (1990) The epidemiology of appendicitis and appendectomy in the United States. Am J Epidemiol 132:910–925
Rybkin AV, Thoeni RF (2007) Current concepts in imaging of appendicitis. Radiol Clin North Am 45:411–422
Kraemer M, Franke C, Ohmann C et al (2000) Acute appendicitis in late adulthood: incidence, presentation, and outcome. Results of a prospective multicenter acute abdominal pain study and review of the literature. Langenbecks Arch Surg 385:470–481
Pickhardt PJ, Lawrence EM, Pooler BD et al (2011) Diagnostic performance of multidetector computed tomography for suspected acute appendicitis. Ann Intern Med 154:789-U38
Brunicardi C, Andersen D, Billiar TR et al (2005) Schwartz's principles of surgery, 8th edn. McGraw-Hill Professional, New York
Anderson BA, Salem L, Flum DR (2005) A systematic review of whether oral contrast is necessary for the computed tomography diagnosis of appendicitis in adults. Am J Surg 190:474–478
Hlibczuk V, Dattaro JA, Jin ZZ et al (2010) Diagnostic accuracy of noncontrast computed tomography for appendicitis in adults: a systematic review. Ann Emerg Med 55:51–59
Terasawa T, Blackmore CC, Bent S et al (2004) Systematic review: computed tomography and ultrasonography to detect acute appendicitis in adults and adolescents. Ann Intern Med 141:537–546
van Randen A, Bipat S, Zwinderman AH et al (2008) Acute appendicitis: meta-analysis of diagnostic performance of CT and graded compression US related to prevalence of disease. Radiology 249:97–106
Weston AR, Jackson TJ, Blamey S (2005) Diagnosis of appendicitis in adults by ultrasonography or computed tomography: a systematic review and meta-analysis. Int J Technol Assess 21:368–379
Franz MG, Norman J, Fabri PJ (1995) Increased morbidity of appendicitis with advancing age. Am Surgeon 61:40–44
Harrell AG, Lincourt AE, Novitsky YW et al (2006) Advantages of laparoscopic appendectomy in the elderly. Am Surgeon 72:474–480
Rub R, Margel D, Soffer D, Kluger Y (2000) Appendicitis in the elderly: what has changed? Israel Med Assoc J 2:220–223
Wen SW, Naylor CD (1995) Diagnostic accuracy and short-term surgical outcomes in cases of suspected acute appendicitis. Can Med Assoc J 152:1617–1626
Paranjape C, Dalia S, Pan J, Horattas M (2007) Appendicitis in the elderly: a change in the laparoscopic era. Surg Endosc 21:777–781
Storm-Dickerson TL, Horattas MC (2003) What have we learned over the past 20 years about appendicitis in the elderly? Am J Surg 185:198–201
Hui TT, Major KM, Avital I, Hiatt JR, Margulies DR (2002) Outcome of elderly patients with appendicitis—effect of computed tomography and laparoscopy. Arch Surg 137:995–998
Pittman-Waller VA, Myers JG, Stewart RM et al (2000) Appendicitis: why so complicated? Analysis of 5755 consecutive appendectomies. Am Surg 66:548–554
Koepsell TD, Inui TS, Farewell WT (1981) Factors affecting perforation in acute appendicitis. Surg Gynecol Obstet 153(4):508–510
Andersson A, Bergdahl L (1978) Acute appendicitis in patients over 60. Am Surg 44:445–447
Lee JFY, Leow CK, Lau WY (2000) Appendicitis in the elderly. Aust N Z J Surg 70:593–596
Guller U, Jain N, Peterson ED, Muhlbaier LH, Eubanks S, Pietrobon R (2004) Laparoscopic appendectomy in the elderly. Surgery 135:479–488
Todd RD, Sarosi GA, Nwariaku F, Anthony T (2004) Incidence and predictors of appendiceal tumors in elderly males presenting with signs and symptoms of acute appendicitis. Am J Surg 188:500–504
Pickhardt PJ, Levy AD, Rohrmann CA, Kende AI (2002) Primary neoplasms of the appendix manifesting as acute appendicitis: CT findings with pathologic comparison. Radiology 224:775–781
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Pooler, B.D., Lawrence, E.M. & Pickhardt, P.J. MDCT for suspected appendicitis in the elderly: diagnostic performance and patient outcome. Emerg Radiol 19, 27–33 (2012). https://doi.org/10.1007/s10140-011-1002-3
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10140-011-1002-3