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Synthesis and characterization of poly(ɛ-caprolactone)/Fe3o4 nanocomposites by in situ polymerization

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Abstract

A series of magnetic nanocomposites based on poly(ɛ-caprolactone) (PCL) and Fe3O4 nanoparticles were prepared using a facile in situ polymerization method. The chemical structures of the PCL/Fe3O4 nanocomposites were characterized by Fourier transform infrared (FTIR) spectroscopy. Results of wide-angle X-ray diffraction (WAXD) showed that the incorporation of the Fe3O4 nanoparticles did not affect the crystallization structure of the PCL. Both scanning electron microscopy (SEM) and transmission electron microscopy (TEM) were used to characterize the morphology and dispersion of the Fe3O4 nanoparticles within the as-synthesized nanocomposites. Results of differential scanning calorimetry (DSC) and polarizing optical microscopy (POM) showed that the crystallization temperature was raised and the spherulites size decreased by the presence of Fe3O4 nanoparticles in the nanocomposites due to the heterogeneous nucleation effect. The thermal stability of the PCL was depressed by incorporation of Fe3O4 nanoparticles from thermogravimetric analysis (TGA). The superparamagnetic behavior of the PCL/Fe3O4 nanocomposites was testified by the superconducting quantum interference device (SQUID) magnetometer analysis. The obtained biodegradable nanocomposites will have a great potential in magnetic resonance imaging contrast and targeted drug delivery.

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Authors and Affiliations

  1. School of Material Science and Engineering, Dalian University of Technology, Dalian, 116024, China

    Guang-shuo Wang, Lin Sang, Xu-feng Dong & Min Qi  (齐民)

  2. Department of Oncology, First Affiliated Hospital of Dalian Medical University, Dalian, 116011, China

    Ling Wang

  3. School of Automotive Engineering, Dalian University of Technology, Dalian, 116024, China

    Zhi-yong Wei  (魏志勇), Guang-yi Chen, Ying Chang & Wan-xi Zhang

Authors
  1. Guang-shuo Wang
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  2. Ling Wang
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  3. Zhi-yong Wei  (魏志勇)
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  4. Lin Sang
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  5. Xu-feng Dong
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  6. Min Qi  (齐民)
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  7. Guang-yi Chen
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  8. Ying Chang
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  9. Wan-xi Zhang
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Corresponding authors

Correspondence to Zhi-yong Wei  (魏志勇) or Min Qi  (齐民).

Additional information

This work was financially supported by the National Natural Science Foundation of China (Nos. 31000427, 50901011, 81271719, 81271720) and the Fundamental Research Funds for the Central Universities (DUT12JB09).

These two authors are joint first authors.

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Wang, Gs., Wang, L., Wei, Zy. et al. Synthesis and characterization of poly(ɛ-caprolactone)/Fe3o4 nanocomposites by in situ polymerization. Chin J Polym Sci 31, 1011–1021 (2013). https://doi.org/10.1007/s10118-013-1255-2

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  • DOI: https://doi.org/10.1007/s10118-013-1255-2

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