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Could violet-blue lights increase the bacteria resistance against ultraviolet radiation mediated by photolyases?

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Abstract

Studies have demonstrated bacterial inactivation by radiations at wavelengths between 400 and 500 nm emitted by low-power light sources. The phototoxic activity of these radiations could occur by oxidative damage in DNA and membrane proteins/lipids. However, some cellular mechanisms can reverse these damages in DNA, allowing the maintenance of genetic stability. Photoreactivation is among such mechanisms able to repair DNA damages induced by ultraviolet radiation, ranging from ultraviolet A to blue radiations. In this review, studies on the effects of violet and blue lights emitted by low-power LEDs on bacteria were accessed by PubMed, and discussed the repair of ultraviolet-induced DNA damage by photoreactivation mechanisms. Data from such studies suggested bacterial inactivation after exposure to violet (405 nm) and blue (425–460 nm) radiations emitted from LEDs. However, other studies showed bacterial photoreactivation induced by radiations at 348–440 nm. This process occurs by photolyase enzymes, which absorb photons at wavelengths and repair DNA damage. Although authors have reported bacterial inactivation after exposure to violet and blue radiations emitted from LEDs, pre-exposure to such radiations at low fluences could activate the photolyases, increasing resistance to DNA damage induced by ultraviolet radiation.

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Funding

This research was supported by Fundação de Amparo à Pesquisa do Estado do Rio de Janeiro (FAPERJ), Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq), and Universidade do Estado do Rio de Janeiro (UERJ).

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  1. Departamento de Biofísica e Biometria, Instituto de Biologia Roberto Alcantara Gomes, Universidade do Estado do Rio de Janeiro, Boulevard Vinte e Oito de Setembro, 87, Fundos, Vila Isabel, Rio de Janeiro, 20551030, Brazil

    Rickson Souza Ribeiro, Andre Luiz Mencalha & Adenilson de Souza da Fonseca

  2. Departamento de Ciências Fisiológicas, Instituto Biomédico, Universidade Federal do Estado do Rio de Janeiro, Rua Frei Caneca, 94, Rio de Janeiro, 20211040, Brazil

    Adenilson de Souza da Fonseca

  3. Centro de Ciências da Saúde, Centro Universitário Serra dos Órgãos, Avenida Alberto Torres, Teresópolis, Rio de Janeiro, 11125964004, Brazil

    Adenilson de Souza da Fonseca

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  1. Rickson Souza Ribeiro
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  2. Andre Luiz Mencalha
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Rickson Souza Ribeiro: conceptualization, methodology, resources, and writing of the original draft. Andre Luiz Mencalha: data curation, visualization, review, and editing. Adenilson de Souza da Fonseca: conceptualization, methodology, review, editing, and supervision.

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Ribeiro, R.S., Mencalha, A.L. & de Souza da Fonseca, A. Could violet-blue lights increase the bacteria resistance against ultraviolet radiation mediated by photolyases?. Lasers Med Sci 38, 253 (2023). https://doi.org/10.1007/s10103-023-03924-w

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