Skip to main content

Advertisement

SpringerLink
Log in

Efficacy of near infrared dental lasers on dentinal hypersensitivity: a meta-analysis of randomized controlled clinical trials

  • Review Article
  • Published:
Lasers in Medical Science Aims and scope Submit manuscript

Abstract

Conventional therapies have aimed to try to help individuals suffering with dentine hypersensitivity (DH/DHS). A relatively new approach, laser therapy claims to be beneficial while having immediate and long-lasting effect. Therefore, our analysis aims to explore the immediate and 1-month efficacy of near-infrared laser (NIR) therapy in treating dentinal hypersensitivity. A systematic literature search conducted in databases, and analysis was undertaken utilizing a meta-analysis approach. Randomized controlled clinical trials comparing near-infrared lasers and placebo/no treatment in patients (> 18 years) were included. The risk of bias for included studies was assessed using Cochrane RoB tool (for randomized studies). Random effects meta-analyses model of standardized mean differences and 95% confidence intervals were performed using RevMan 5.4 software. A comprehensive electronic and manual search yielded a total of 1081 potential articles. Following the implementation of the inclusion and exclusion criteria, a total of 6 studies were included in the analysis. Near-infrared laser therapy led to statistical significant reduction in immediate and 1-month follow-up VAS (visual analog scale) scores compared to placebo/no treatment (p < 0.05). Statistical heterogeneity across the studies was high (I2-96%). The findings suggest that near-infrared laser therapy does have a significant immediate effect in reducing dentine hypersensitivity compared to placebo/no treatment. Furthermore, this effect is not diminished and endured at 1-month follow-up.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6

Similar content being viewed by others

Data availability

Not applicable.

Code availability

Not applicable.

References

  1. Curro FA (1990) Tooth hypersensitivity in the spectrum of pain. Dent Clin North Am 34:429–437

    CAS  PubMed  Google Scholar 

  2. Canadian Advisory Board on Dentin Hypersensitivity (2003) Consensus-based recommendations for the diagnosis and management of dentin hypersensitivity. J Can Dent Assoc 69:221–226

    Google Scholar 

  3. Rees JS, Addy M (2004) A cross-sectional study of buccal cervical sensitivity in UK general dental practice and a summary review of prevalence studies. Int J Dent Hyg 2:64–69. https://doi.org/10.1111/j.1601-5029.2004.00068.x

    Article  CAS  PubMed  Google Scholar 

  4. Pashley DH, Tay F, Haywood VB, Collins MA, Drisko CL (2008) Dentin hypersensitivity: consensus - based recommendations for the diagnosis and management of dentin hypersensitivity. Compend Contin Educ Dent 8:1–37

    Google Scholar 

  5. West NX, Lussi A, Seong J, Hellwig E (2013) Dentin hypersensitivity: pain mechanisms and aetiology of exposed cervical dentin. Clin Oral Investig 17:S9–S19. https://doi.org/10.1007/s00784-012-0887-x

    Article  PubMed  Google Scholar 

  6. Magloire H, Maurin JC, Couble ML, Shibukawa Y, Tsumura M, Thivichon-Prince B, Bleicher F (2010) Topical review. Dental pain and odontoblasts: facts and hypotheses. J Orofac Pain 24:335–349

    PubMed  Google Scholar 

  7. Panagakos F, Schiff T, Guignon A (2009) Dentin hypersensitivity: effective treatment with an in-office desensitizing paste containing 8% arginine and calcium carbonate. Am J Dent 22:3A-7A

    PubMed  Google Scholar 

  8. Schmalz G, Hellwig F, Mausberg RF, Schneider H, Krause F, Haak R, Ziebolz D (2017) Dentin protection of different desensitizing varnishes during stress simulation: an in vitro study. Oper Dent 42:E35–E43. https://doi.org/10.2341/16-068-l

    Article  CAS  PubMed  Google Scholar 

  9. Lin PY, Cheng YW, Chu CY, Chien KL, Lin CP, Tu YK (2013) In-office treatment for dentin hypersensitivity: a systematic review and network meta-analysis. J Clin Periodontol 40:53–64. https://doi.org/10.1111/jcpe.12011

    Article  CAS  PubMed  Google Scholar 

  10. Asnaashari M, Moeini M (2013) Effectiveness of lasers in the treatment of dentin hypersensitivity. J Lasers Med Sci 4:1–7

    PubMed  PubMed Central  Google Scholar 

  11. Sgolastra F, Petrucci A, Severino M, Gatto R, Monaco A (2013) Lasers for the treatment of dentin hypersensitivity: a meta-analysis. J Dent Res 92:492–499. https://doi.org/10.1177/0022034513487212

    Article  CAS  PubMed  Google Scholar 

  12. Kong Y, Lei Y, Li S, Zhang Y, Han J, Hu M (2020) Network meta-analysis of the desensitizing effects of lasers in patients with dentine hypersensitivity. Clin Oral Investig 24:1917–1928. https://doi.org/10.1007/s00784-019-03051-3

    Article  PubMed  Google Scholar 

  13. Higgins JP, Altman DG, Gotzsche PC, Juni P, Moher D, Oxman AD, et al (2011) The cochrane collaboration’s tool for assessing risk of bias in randomised trials. BMJ 343:d5928. https://doi.org/10.1136/bmj.d5928

  14. Higgins JP, Thompson SG (2002) Quantifying heterogeneity in a meta-analysis. Stat Med 21:1539–1558. https://doi.org/10.1002/sim.1186

    Article  PubMed  Google Scholar 

  15. Hunter J, Schmidt F (2000) Fixed effects vs. random effects meta-analysis models: implications for cumulative research knowledge. Int JSelAssess 8:275–292. https://doi.org/10.1111/1468-2389.00156

    Article  Google Scholar 

  16. Petrie A, Bulman J, Osborn J (2003) Further statistics in dentistry Part 8: systematic reviews and meta-analyses. Br Dent J 194:73–78. https://doi.org/10.1038/sj.bdj.4809877

    Article  CAS  PubMed  Google Scholar 

  17. Duval S, Tweedie R (2000) Trim and fill: a simple funnel-plot-based method of testing and adjusting for publication bias in meta-analysis. Biometrics 56:455–463. https://doi.org/10.1111/j.0006-341x.2000.00455.x

    Article  CAS  PubMed  Google Scholar 

  18. Moher D, Liberati A, Tetzlaff J, Altman DG, The PRISMA Group (2009) Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. PLoS Med 6(7):e1000097. https://doi.org/10.1371/journal.pmed1000097

    Article  PubMed  PubMed Central  Google Scholar 

  19. Lier BB, Rösing CK, Aass AM, Gjermo P (2002) Treatment of dentin hypersensitivity by Nd:YAG laser. J Clin Periodontol 29:501–506. https://doi.org/10.1034/j.1600-051x.2002.290605.x

    Article  CAS  PubMed  Google Scholar 

  20. Birang R, Poursamimi J, Gutknecht N, Lampert F, Mir M (2007) Comparative evaluation of the effects of Nd:YAG and Er:YAG laser in dentin hypersensitivity treatment. Lasers Med Sci 22:21–24. https://doi.org/10.1007/s10103-006-0412-z

    Article  PubMed  Google Scholar 

  21. Maximiano V, Machado AC, Yoshida ML, Pannuti CM, Scaramucci T, Aranha AC (2018) Nd:YAG laser and calcium sodium phosphosilicate prophylaxis paste in the treatment of dentin hypersensitivity: a double-blind randomized clinical study. Clin Oral Investig 23:3331–3338. https://doi.org/10.1007/s00784-018-2759-5

    Article  PubMed  Google Scholar 

  22. Bal MV, Keskiner I, Sezer U, Acikel C, Saygun I (2015) Comparison of low level laser and arginine-calcium carbonate alone or combination in the treatment of dentin hypersensitivity: a randomized split-mouth clinical study. Photomed Laser Surg 33:200–205. https://doi.org/10.1089/pho.2014.3873

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  23. Yilmaz H, Kurtulmus-Yilmaz S, Cengiz E, Bayindir H, Aykac Y (2011) Clinical evaluation of Er, Cr: YSGG and GaAlAs laser therapy for treating dentine hypersensitivity: a randomized controlled clinical trial. J Dentistry 39:249–254. https://doi.org/10.1016/j.jdent.2011.01.003

    Article  Google Scholar 

  24. Yilmaz HG, Kurtulmus-Yilmaz S, Cengiz E (2011) Long-term effect of diode laser irradiation compared to sodium fluoride varnish in the treatment of dentine hypersensitivity in periodontal main- tenance patients: a randomized controlled clinical study. Photomed Laser Surg 29:721–725. https://doi.org/10.1089/pho.2010.2974

    Article  CAS  PubMed  Google Scholar 

  25. Marto CM, Baptista Paula A, Nunes T, Pimenta M, Abrantes AM, Pires AS et al (2019) Evaluation of the efficacy of dentin hypersensitivity treatments-a systematic review and follow-up analysis. J Oral Rehabil 46(10):952–990. https://doi.org/10.1111/joor.12842

    Article  CAS  PubMed  Google Scholar 

  26. Gillam DG (2015) Management of dentin hypersensitivity. Curr Oral Health Rep 2:87–94. https://doi.org/10.1007/s40496-015-0047-x

    Article  Google Scholar 

  27. Karcioglu O, Topacoglu H, Dikme O, Dikme O (2018) A systematic review of the pain scales in adults: which to use? Am J Emerg Med 36(4):707–714. https://doi.org/10.1016/j.ajem.2018.01.008

    Article  PubMed  Google Scholar 

  28. Idon PI, Sotunde OA, Ogundare TO (2009) Beyond the relief of pain: dentin hypersensitivity and oral health-related quality of life. Front Dent 16(5):325–334. https://doi.org/10.18502/fid.v16i5.2272

    Article  Google Scholar 

  29. Hu ML, Zheng G, Han JM, Yang M, Zhang YD, Lin H (2019) Effect of lasers on dentine hypersensitivity: evidence from a meta-analysis. J Evid Based Dent Pract 19:115–130. https://doi.org/10.1016/j.jebdp.2018.12.004

    Article  PubMed  Google Scholar 

  30. Davari A, Ataei E, Assarzadeh H (2013) Dentin hypersensitivity: etiology, diagnosis and treatment; a literature review. J Dent (Shiraz) 149(3):136–145

    Google Scholar 

  31. Lan WH, Lee BS, Liu HC, Lin CP (2004) Morphologic study of Nd:YAG laser usage in treatment of dentinal hypersensitivity. J Endod 30:131–134. https://doi.org/10.1097/00004770-200403000-00001

    Article  PubMed  Google Scholar 

  32. Aranha AC, Pimenta LA, Marchi GM (2009) Clinical evaluation of desensitizing treatments for cervical dentin hypersensitivity. Braz Oral Res 23:333–339. https://doi.org/10.1590/s1806-83242009000300018

    Article  PubMed  Google Scholar 

  33. Yilmaz HG, Cengiz E, Kurtulmus-Yilmaz S, Leblebicioglu B (2011) Effectiveness of Er, Cr:YSGG laser on dentine hypersensitivity: a controlled clinical trial. J Clin Periodontol 38:341–346. https://doi.org/10.1111/j.1600-051x.2010.01694.x

    Article  PubMed  Google Scholar 

  34. Parker S, Cronshaw M, Anagnostaki E, Mylona V, Lynch E, Grootveld M (2020) Current concepts of laser tissue interaction. Dent J (Basel) 8(3):61. https://doi.org/10.3390/dj8030061

    Article  Google Scholar 

  35. Kreisler M, Al-Haj H, D’Hoedt B (2002) Intrapulpal temperature changes during root surface irradiation with an 809-nm GaAlAs laser. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 93(6):730–735. https://doi.org/10.1067/moe.2002.124766

    Article  PubMed  Google Scholar 

  36. Turner RM, Bird SM, Higgins JP (2013) The impact of study size on meta - analyses: examination of underpowered studies in cochrane reviews. PLoS ONE 8:e59202. https://doi.org/10.1371/journal.pone.0059202

    Article  CAS  PubMed  PubMed Central  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Bapuji Dental College and Hospital, Davangere, Karnataka State, India

    Shivani Bellal, Abha Mehta & Arunkumar Namachivayam

  2. Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, 16132, Genoa, Italy

    Shivani Bellal, Rita El Feghali & Stefano Benedicenti

Authors
  1. Shivani Bellal
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Rita El Feghali
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Abha Mehta
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Arunkumar Namachivayam
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Stefano Benedicenti
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Shivani Bellal.

Ethics declarations

Ethics approval

Not applicable.

Consent to participate

Not applicable.

Consent for publication

Not applicable.

Conflict of interest

The authors declare no competing interests.

Additional information

Publisher's note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Bellal, S., Feghali, R.E., Mehta, A. et al. Efficacy of near infrared dental lasers on dentinal hypersensitivity: a meta-analysis of randomized controlled clinical trials . Lasers Med Sci 37, 733–744 (2022). https://doi.org/10.1007/s10103-021-03391-1

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10103-021-03391-1

Keywords

Search

Navigation