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Enterococcus raffinosus bacteremia: clinical experience with 49 adult patients

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Abstract

This study is to evaluate the clinical characteristics and outcomes of Enterococcus raffinosus bacteremia in adults. We analyzed the medical records of adult patients with E. raffinosus bacteremia who were diagnosed and treated between 1997 and 2020 at a tertiary care teaching hospital in Seoul, Republic of Korea. The demographic, clinical, and laboratory data were collected and assessed. A total of 49 cases of E. raffinosus bacteremia were identified. E. raffinosus accounted for 0.6% of all enterococcal bacteremia events, and the incidence was 0.02 cases per 1,000 admissions. Of the 49 cases of E. raffinosus bacteremia, 35 (71.4%) had underlying malignancy. The biliary tract was the most common source of infection (81.6%, 40/49) and polymicrobial bacteremia was found in 25 cases (51.0%). The resistance rates of E. raffinosus bacteremia cases to penicillin, ampicillin, vancomycin, and linezolid were 61.2%, 49.0%, 2.0%, and 0%, respectively. In our case series, there was one case of vanA-type vancomycin-resistant E. raffinosus. The all-cause 60-day mortality rate was 22.4% (11/49), and the E. raffinosus bacteremia-related mortality rate was 4.1% (2/49). Cases of E. raffinosus bacteremia mainly originated from biliary tract infection and had a low rate of bacteremia-related mortality.

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Authors and Affiliations

  1. Department of Infectious Diseases, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, Republic of Korea

    Yun Woo Lee, So Yun Lim, Jiwon Jung, Min Jae Kim, Yong Pil Chong, Sung-Han Kim, Sang-Oh Lee, Yang Soo Kim & Sang-Ho Choi

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  1. Yun Woo Lee
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  2. So Yun Lim
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  3. Jiwon Jung
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  4. Min Jae Kim
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  5. Yong Pil Chong
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  6. Sung-Han Kim
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  7. Sang-Oh Lee
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  8. Yang Soo Kim
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  9. Sang-Ho Choi
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Correspondence to Sang-Ho Choi.

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This study was approved by the Institutional Review Board of Asan Medical Center (IRB No. 2021–0843).

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Lee, Y.W., Lim, S.Y., Jung, J. et al. Enterococcus raffinosus bacteremia: clinical experience with 49 adult patients. Eur J Clin Microbiol Infect Dis 41, 415–420 (2022). https://doi.org/10.1007/s10096-021-04389-x

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  • DOI: https://doi.org/10.1007/s10096-021-04389-x

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