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Factors associated with recurrence of catheter-related bloodstream infections in home parenteral nutrition patients

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Abstract

Blood cultures from outpatients receiving home parenteral nutrition (HPN) via long-term central venous access (CVA) were retrospectively analyzed from January 2003 to May 2009. When infection of the CVA was not due to Staphylococcus aureus, Pseudomonas aeruginosa, or Candida, catheter salvage was attempted for a maximum of three consecutive infections on the same CVA. Factors influencing the time-to-next-infection were studied, whether the catheter was changed after the last infection or not. Neither the McCabe score, age, history of cancer, diabetes mellitus nor immunosuppression, curative antibiotic lock, type of bacteria, type or duration of treatment had an influence on the time-to-next-infection. The time-to-next-infection was significantly associated with the status of CVA (saved or changed) and its type (tunneled catheter with or without a cuff, or implanted port catheter).

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References

  1. Mermel LA, Allon M, Bouza E, Craven DE, Flynn P, O’Grady NP, Raad II, Rijnders BJ, Sherertz RJ, Warren DK (2009) Clinical practice guidelines for the diagnosis and management of intravascular catheter-related infection: 2009 Update by the Infectious Diseases Society of America. Clin Infect Dis 49(1):1–45

    Article  PubMed  CAS  Google Scholar 

  2. McCabe WR, Jackson GG (1962) Gram-negative bacteremia: I. Etiology and ecology. Arch Intern Med 110(6):847–855

    Article  Google Scholar 

  3. Tokars JI, Cookson ST, McArthur MA, Boyer CL, McGeer AJ, Jarvis WR (1999) Prospective evaluation of risk factors for bloodstream infection in patients receiving home infusion therapy. Ann Intern Med 131(5):340–347

    PubMed  CAS  Google Scholar 

  4. Santarpia L, Pasanisi F, Alfonsi L, Violante G, Tiseo D, De Simone G, Contaldo F (2002) Prevention and treatment of implanted central venous catheter (CVC)-related sepsis: a report after six years of home parenteral nutrition (HPN). Clin Nutr 21(3):207–211

    Article  PubMed  Google Scholar 

  5. Reimund JM, Arondel Y, Finck G, Zimmermann F, Duclos B, Baumann R (2002) Catheter-related infection in patients on home parenteral nutrition: results of a prospective survey. Clin Nutr 21(1):33–38

    Article  PubMed  Google Scholar 

  6. Bozzetti F, Mariani L, Bertinet DB, Chiavenna G, Crose N, De Cicco M, Gigli G, Micklewright A, Moreno Villares JM, Orban A, Pertkiewicz M, Pironi L, Vilas MP, Prins F, Thul P (2002) Central venous catheter complications in 447 patients on home parenteral nutrition: an analysis of over 100.000 catheter days. Clin Nutr 21(6):475–485

    Article  PubMed  CAS  Google Scholar 

  7. Raad I, Kassar R, Ghannam D, Chaftari AM, Hachem R, Jiang Y (2009) Management of the catheter in documented catheter-related coagulase-negative staphylococcal bacteremia: remove or retain? Clin Infect Dis 49(8):1187–1194

    Article  PubMed  Google Scholar 

  8. Rao JS, O’Meara A, Harvey T, Breatnach F (1992) A new approach to the management of Broviac catheter infection. J Hosp Infect 22(2):109–116

    Article  PubMed  CAS  Google Scholar 

  9. Capdevila JA, Segarra A, Planes AM, Ramírez-Arellano M, Pahissa A, Piera L, Martínez-Vázquez JM (1993) Successful treatment of haemodialysis catheter-related sepsis without catheter removal. Nephrol Dial Transplant 8(3):231–234

    PubMed  CAS  Google Scholar 

  10. Maki DG, Kluger DM, Crnich CJ (2006) The risk of bloodstream infection in adults with different intravascular devices: a systematic review of 200 published prospective studies. Mayo Clin Proc 81(9):1159–1171

    Article  PubMed  Google Scholar 

  11. O’Grady NP, Alexander M, Dellinger EP, Gerberding JL, Heard SO, Maki DG, Masur H, McCormick RD, Mermel LA, Pearson ML, Raad II, Randolph A, Weinstein RA (2002) Guidelines for the prevention of intravascular catheter-related infections. Centers for Disease Control and Prevention. MMWR Recomm Rep 51(RR-10):1–29

    PubMed  Google Scholar 

  12. Horattas MC, Trupiano J, Hopkins S, Pasini D, Martino C, Murty A (2001) Changing concepts in long-term central venous access: catheter selection and cost savings. Am J Infect Control 29(1):32–40

    Article  PubMed  CAS  Google Scholar 

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Acknowledgments

There is no conflict of interest. The authors are particularly grateful to Marie-Beatrice Hasbrouck, the home parenteral nutrition nurse, for her incomparable help in the technical management of the data.

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Authors and Affiliations

  1. Service de Médecine Interne et de Maladies Infectieuses, CHU de Poitiers, 86000, Poitiers, France

    G. Béraud

  2. Service de Nutrition, EA2694, Université Lille Nord de France, 59000, Lille, France

    D. Seguy

  3. Service de Maladies Infectieuses, Hôpital Dron, Tourcoing, France

    S. Alfandari

  4. Département d’Information Médicale, CHRU de Lille, 59000, Lille, France

    X. Lenne

  5. Service de Maladies Infectieuses, CHRU de Lille, 59000, Lille, France

    F. Leburgue, K. Faure & B. Guery

  6. Service de Médecine Interne et de Maladies Infectieuses, Centre Hospitalier Universitaire de Poitiers, 2, rue de la Milétrie, BP 577, 86021, Poitiers Cedex, France

    G. Béraud

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  1. G. Béraud
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  2. D. Seguy
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  3. S. Alfandari
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  4. X. Lenne
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  5. F. Leburgue
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  6. K. Faure
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  7. B. Guery
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Correspondence to G. Béraud.

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Béraud, G., Seguy, D., Alfandari, S. et al. Factors associated with recurrence of catheter-related bloodstream infections in home parenteral nutrition patients. Eur J Clin Microbiol Infect Dis 31, 2929–2933 (2012). https://doi.org/10.1007/s10096-012-1643-5

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  • DOI: https://doi.org/10.1007/s10096-012-1643-5

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