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Dengue: an arthropod-borne disease of global importance

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Abstract

Dengue viruses cause a variable spectrum of disease that ranges from an undifferentiated fever to dengue fever to the potentially fatal dengue shock syndrome. Due to the increased incidence and geographical distribution of dengue in the last 50 years, dengue is becoming increasingly recognised as one of the world’s major infectious diseases. This article will review clinical and diagnostic aspects of dengue virus infections. It also presents our current knowledge of the pathophysiology of severe dengue and addresses the importance of dengue virus infections in those travelling to parts of the world where dengue is endemic.

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Acknowledgement

The Royal Netherlands Academy of Arts and Sciences funded a project on Dengue virus infections (project number 99-MED-04) in which all authors are involved. Funding sources had no involvement in the writing of this report.

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  1. Department of Internal Medicine, Slotervaart Hospital, Louwesweg 6, 1066 EC, Amsterdam, The Netherlands

    A. T. A. Mairuhu, J. Wagenaar, D. P. M. Brandjes & E. C. M. van Gorp

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  1. A. T. A. Mairuhu
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  2. J. Wagenaar
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  3. D. P. M. Brandjes
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  4. E. C. M. van Gorp
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Correspondence to A. T. A. Mairuhu.

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Mairuhu, A.T.A., Wagenaar, J., Brandjes, D.P.M. et al. Dengue: an arthropod-borne disease of global importance. Eur J Clin Microbiol Infect Dis 23, 425–433 (2004). https://doi.org/10.1007/s10096-004-1145-1

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