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Failure to Detect Chlamydia pneumoniae by Cell Culture and Polymerase Chain Reaction in Major Arteries of 93 Patients with Atherosclerosis

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Abstract

To detect Chlamydia pneumoniae in punch specimens of the aortic wall of 61 patients undergoing coronary-aortic bypass graft, and carotid atheromas of 32 patients undergoing carotid endarterectomy, cell culture (HEp-2 cells) and two polymerase chain reaction assays in two different laboratories were used. All cultures and polymerase chain reaction tests for Chlamydia pneumoniae were negative. Further studies are required to explore the complex relationship between Chlamydia pneumoniae and atherosclerosis.

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Acknowledgements

The authors thank Phyllis Curchack Kornspan for her secretarial and editing services.

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Authors and Affiliations

  1. Department of Internal Medicine "C", Rabin Medical Centre, Beilinson Campus, Sackler School of Medicine, Tel Aviv University, Petach Tikvah, Israel

    J. Bishara, S. Pitlik & A. Kazakov

  2. Infectious Diseases Unit, Rabin Medical Centre, Beilinson Campus, Sackler School of Medicine, Tel Aviv University, Petach Tikvah, Israel

    J. Bishara & S. Pitlik

  3. Department of Thoracic Surgery, Rabin Medical Centre, Rabin Medical Centre, Sackler School of Medicine, Tel Aviv University, Petach Tikvah, Israel

    G. Sahar

  4. Department of Vascular Surgery, Rabin Medical Centre, Beilinson Campus, Sackler School of Medicine, Tel Aviv University, Petach Tikvah, Israel

    M. Haddad

  5. Immunosciences Lab, Inc., Beverly Hills, Drew University School of Medicine and Science, Los Angeles, CA, USA

    A. Vojdani

  6. Department of Microbiology, Chlamydia and Mycoplasma National Centre, Rabin Medical Centre, Beilinson Campus, Sackler School of Medicine, Tel Aviv University, Petach Tikvah, Israel

    S. Rosenberg & Z. Samra

Authors
  1. J. Bishara
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  2. S. Pitlik
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  3. A. Kazakov
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  4. G. Sahar
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  5. M. Haddad
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  6. A. Vojdani
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  7. S. Rosenberg
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  8. Z. Samra
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Correspondence to J. Bishara.

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Bishara, J., Pitlik, S., Kazakov, A. et al. Failure to Detect Chlamydia pneumoniae by Cell Culture and Polymerase Chain Reaction in Major Arteries of 93 Patients with Atherosclerosis. Eur J Clin Microbiol Infect Dis 22, 300–302 (2003). https://doi.org/10.1007/s10096-003-0912-8

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  • DOI: https://doi.org/10.1007/s10096-003-0912-8

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