Abstract.
Phenytoin hypersensitivity syndrome (PHS) is a rare, and important entity characterized by rash, fever, lymphadenopathy, leukocytosis with atypical lymphocytes, eosinophilia and associated hepatitis. In this article, we present the clinical, laboratory and histopathologic results of 5 cases of PHS. In therapy, pheyntoin was stopped and sodium valproate (10–20 mg/kg day) was started. Additionally, prednisolone was given in two patients who had not resolved eruption with conservative therapy.
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Received: 2 January 2001 / Accepted in revised form: 24 May 2001
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Güngör, E., Alli, N., Çomoğlu, S. et al. Phenytoin hypersensitivity syndrome. Neurol Sci 22, 261–265 (2001). https://doi.org/10.1007/s100720100024
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DOI: https://doi.org/10.1007/s100720100024