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Acute subdural hemorrhage associated with rifampicin-induced thrombocytopenia

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Abstract

Thrombocytopenia is a major adverse effect of several drug treatments. Rifampicin has been recognized as a cause of immune thrombocytopenia. A 68-year-old woman diagnosed with pulmonary tuberculosis was taking the standard four-drug antituberculosis regimen for 4 months. She presented with decreased responsiveness and headache. Brain MRI revealed subdural hemorrhage along the falx cerebri and high convexity. The platelet count was 8,000 μL−1. Intracranial hemorrhage due to rifampicin-induced thrombocytopenia has not, to our knowledge, been previously reported. We report a patient with acute subdural hemorrhage associated with rifampicin-induced thrombocytopenia.

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The authors report no conflicts of interest.

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Authors and Affiliations

  1. Department of Neurology, College of Medicine, Cheju National University, Jeju, South Korea

    Sa-Yoon Kang, Jay Chol Choi, Ji-Hoon Kang & Jung Seok Lee

  2. Department of Neurology, Cheju National University School of Medicine, 1 Ara 1-dong, Jeju-si, Jeju, 690-756, South Korea

    Sa-Yoon Kang

  3. Department of Neurology, College of Medicine, Inha University, 7-206, 3-ga, Sinheung-dong, Jung-gu, Incheon, 400-711, South Korea

    Sa-Yoon Kang

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  1. Sa-Yoon Kang
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  2. Jay Chol Choi
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  3. Ji-Hoon Kang
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  4. Jung Seok Lee
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Correspondence to Sa-Yoon Kang.

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Kang, SY., Choi, J.C., Kang, JH. et al. Acute subdural hemorrhage associated with rifampicin-induced thrombocytopenia. Neurol Sci 31, 199–200 (2010). https://doi.org/10.1007/s10072-009-0187-7

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  • DOI: https://doi.org/10.1007/s10072-009-0187-7

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