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Monitoring of trimethoprim antibiotic residue in livestock and marine products commercialized in Korea

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Abstract

A survey for trimethoprim (TMP) was performed using 369 livestock and marine products distributed in Korea. Product samples included beef, pork, milk, egg, chicken, flatfish, jacopever, common eel, and shrimp. TMP residues were analyzed using ultra performance LC with electrospray ionization tandem mass spectrometry (UPLC-ESI-MS/MS). The analytical method was validated according to FDA (U.S. Food and Drug Administration) guidelines and all results fully complied with FDA recommendations. TMP was detected in 7 product samples (1.9% incidence), including 5 jacopever, 1 flatfish, and 1 common eel. Residue levels were 1.17 to 16.43 μg/kg in jacopever, 40.0 μg/kg in flatfish, and 13.3 μg/kg in common eel. All positive product samples were below the legal residue limit of 20- 50 μg/kg in the Korean food code.

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Authors and Affiliations

  1. Department of Biochemistry, College of Veterinary Medicine, Seoul National University, Seoul, 08826, Korea

    Jin-wook Jang

  2. Food safety evaluation Department, National institute of food and drug safety evaluation, Cheongju, Chungbuk, 28159, Korea

    Kwang-soo Lee

  3. Center for Food & Drug Analysis, Busan Regional Food and Drug Administration, Busan, 48562, Korea

    Jin-wook Jang & Woo Seong Kim

Authors
  1. Jin-wook Jang
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  2. Kwang-soo Lee
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  3. Woo Seong Kim
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Correspondence to Jin-wook Jang.

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Jang, Jw., Lee, Ks. & Kim, W.S. Monitoring of trimethoprim antibiotic residue in livestock and marine products commercialized in Korea. Food Sci Biotechnol 24, 1927–1931 (2015). https://doi.org/10.1007/s10068-015-0254-1

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  • DOI: https://doi.org/10.1007/s10068-015-0254-1

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