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Development of chemometric models using infrared spectroscopy (MID-FTIR) for detection of sulfathiazole and oxytetracycline residues in honey

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Abstract

Chemometric models using mid-infrared (MID-FTIR) spectroscopy were developed for detection and quantification of oxytetracycline and sulfathiazole contamination in honey samples. Low standard error of calibration (SEC) and prediction (SEP) values were achieved using a partial least squares algorithm (SEC= 1.02 and SEP=1.39 for oxytetracycline and SEC=1.24 and SEP=1.79 for sulfathiazole). Chemometric model-predicted concentrations of antibiotics were compared with ELISA results with coefficient of determination R 2=0.8577 for oxytetracycline and R 2=0.8216 for sulfathiazole. Classification of antibiotic contaminated honey samples and uncontaminated samples was carried out using Soft Independent Modeling Class Analogy analysis with a 100% correct classification rate with interclass distances in the range of 6.93–13.3. MID-FTIR chemometric models developed for detection and quantification of oxitetracycline and sulfathiazole in honey samples have been demonstrated.

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Authors and Affiliations

  1. Department of Biophysics, National School of Biological Sciences, National Polytechnic Institute of Mexico, Prolongación de Carpio y Plan de Ayala S/N. Col, Santo Tomás, CP 11340, México

    Karina Uribe Hernández, Tzayhrí Gallardo Velázquez, Guillermo Osorio Revilla & Maylet Hernández Martínez

  2. Center of Interdisciplinary Research and Regional Development of the State of Durango, National Polytechnic Institute of México, Sigma 119, Fracc. 20 de Noviembre II, Durango, Dgo., México

    Norma Almaraz Abarca

Authors
  1. Karina Uribe Hernández
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  2. Tzayhrí Gallardo Velázquez
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  3. Guillermo Osorio Revilla
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  4. Norma Almaraz Abarca
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  5. Maylet Hernández Martínez
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Correspondence to Tzayhrí Gallardo Velázquez.

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Hernández, K.U., Velázquez, T.G., Revilla, G.O. et al. Development of chemometric models using infrared spectroscopy (MID-FTIR) for detection of sulfathiazole and oxytetracycline residues in honey. Food Sci Biotechnol 24, 1219–1226 (2015). https://doi.org/10.1007/s10068-015-0156-2

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  • DOI: https://doi.org/10.1007/s10068-015-0156-2

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