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DNA protection and antioxidant and anti-inflammatory activities of water extract and fermented hydrolysate of abalone (Haliotis discus hannai Ino)

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Abstract

Antioxidant and anti-inflammatory activities of water extract and fermented hydrolysate of abalone (Haliotis discus hannai Ino) were examined. Experimental models were used to characterize the antioxidant activities, which were compared with the standard antioxidants α-tocoferol and EDTA (ethylenediamine tetraacetic acid). Antioxidant activities of water extract and fermented hydrolysate were examined at the cellular level and evaluated for anti-inflammatory activities in LPS (lipopolysaccharides)-stimulated murine RAW 264.7 macrophages. Production of the pro-inflammatory mediators nitric oxide (NO) and prostaglandin (PGE2) was significantly (p<0.05) inhibited by treatments with abalone water extract and fermented hydrolysate, compared with controls. Abalone (Haliotis discus hannai Ino) can be considered as a potential source of natural antioxidants and dietary supplements.

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Authors and Affiliations

  1. Department of Applied Biochemistry, College of Biomedical and Health Science, Konkuk University, Chungju, Chungbuk, 380-701, Korea

    Md. Abul Hasnat, Mehnaz Pervin, Da Hye Kim, Young Jun Kim & Beong Ou Lim

  2. R&D Center, Naturetech Co., Ltd., Jincheon, Chungbuk, 365-853, Korea

    Jeong Jun Lee & Han Jong Pyo

  3. Euro-Costech Co., Ltd., Hongseong, Chungnam, 350-863, Korea

    Chung Woo Lee

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  1. Md. Abul Hasnat
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  2. Mehnaz Pervin
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  3. Da Hye Kim
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  4. Young Jun Kim
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  7. Chung Woo Lee
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  8. Beong Ou Lim
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Correspondence to Beong Ou Lim.

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Hasnat, M.A., Pervin, M., Kim, D.H. et al. DNA protection and antioxidant and anti-inflammatory activities of water extract and fermented hydrolysate of abalone (Haliotis discus hannai Ino). Food Sci Biotechnol 24, 689–697 (2015). https://doi.org/10.1007/s10068-015-0090-3

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  • DOI: https://doi.org/10.1007/s10068-015-0090-3

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