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Change in the content of phenolic compounds and antioxidant activity during manufacturing of black raspberry (Rubus coreanus Miq.) wine

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Abstract

The changes in total phenolics, total anthocyanins, gallic acid (GA), and 3,4-dihydroxybenzoic acid (DHBA) contents during black raspberry (BR, Rubus coreanus) wine manufacturing were investigated. Total phenolic content gradually increased during BR wine manufacturing. The total anthocyanin content slightly increased, but the changes were not significant. The GA and DHBA in BR wine were detected as main compounds and their content greatly increased during manufacturing. The DPPH radical-scavenging activity was also increased during BR wine manufacturing. In particular, the antioxidant activity in the blood plasma of rats administered with BR wine concentrate was significantly higher than those administered with BR fruit extracts in inhibition of copper ion-induced cholesteryl ester hydroperoxide formation. These results indicate that an increase in antioxidant activity of BR wine may be due to low molecular phenolic compounds including GA and DHBA produced during the manufacturing.

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References

  1. Eu GS, Chung BY, Bandopadhyay R, Yoo NH, Choi DC, Yun SY. Phylogenic relationships of Rubus species revealed by randomly amplified polymorphic DNA markers. J. Crop Sci. Biotechnol. 11: 39–44 (2008)

    Google Scholar 

  2. Do SH, Lee JW, Chung JY, Park SJ, Hong IH, Jeong SK, Lee IS, Jeong KS. Bone-protecting effect of Rubus coreanus by dual regulation of osteoblasts and osteoclasts. Menopause 15: 676–683 (2008)

    Article  Google Scholar 

  3. Park JH, Seong NS, Lee HS, Mun HC, Kim DH, Jung HG, Lee HY. Improvement of anticancer activation of ultrasonificated extracts from Acanthopanax senticosus Harms, Ephedra sinica Stapf, Rubus coreanus Miq. and Artemisia capillaris Thunb. Korean J. Med. Crop Sci. 12: 273–278 (2004)

    Google Scholar 

  4. Lee MK, Lee HS, Choi GP, Oh DH, Kim JD, Yu CY, Lee HY. Screening of biological activities of the extracts from Rubus coreanus Miq. Korean J. Med. Crop Sci. 11: 5–12 (2003)

    Google Scholar 

  5. Yoon I, Cho JY, Kook JH, Wee JH, Jang MY, Ahn TH, Park KH. Identification and activity of antioxidative compounds from Rubus coreanum fruit. Korean J. Food Sci. Technol. 34: 898–904 (2002)

    Google Scholar 

  6. Chung TH, Kim JC, Lee CY, Moon MK, Chae SC, Lee IS, Kim SH, Hahn KS, Lee IP. Potential antiviral effects of Terminalia chebula, Sanguisorba officinalis, Rubus coreanus and Rheum palmatum against duck hepatitis B virus (DHBV). Phytother. Res. 11: 179–182 (1997)

    Article  Google Scholar 

  7. Jeong JH, Jung H, Lee SR, Lee HJ, Hwang KT, Kim TY. Antioxidant, anti-proliferative and anti-inflammatory activities of the extracts from black raspberry fruits and wine. Food Chem. 123: 338–344 (2010)

    Article  CAS  Google Scholar 

  8. Tulio AZ Jr, Reese RN, Wyzgoski FJ, Rinaldi RL, Fu R, Scheerens JC, Miller AR. Cyanidin 3-rutinoside and cyanidin 3-xylosylrutinoside as primary phenolic antioxidant in black raspberry. J. Agr. Food Chem. 56: 1880–1888 (2008)

    Article  CAS  Google Scholar 

  9. Ohtani K, Miyajima C, Takahasi T, Kasai R, Tanaka O, Hahn DR, Naruhashi N. A dimeric triterpene-glycoside from Rubus coreanus. Phytochemistry 29: 3275–3280 (1990)

    Article  CAS  Google Scholar 

  10. Kim YH, Kang SS. Triterpenoids from Rubi Fructus (bogbunja). Arch. Pharm. Res. 16: 109–113 (1993)

    Article  CAS  Google Scholar 

  11. Choi JW, Lee KT, Ha JH, Yun SY, Ko CD, Jung HJ, Park HJ. Antinociceptive and antiinflammatory effects of niga-ichigoside F1 and 23-hydroxytormentic acid obtained from Rubus coreanus. Biol. Pharm. Bull. 26: 1436–1441 (2003)

    Article  CAS  Google Scholar 

  12. Cho JY, Yoon I, Jung DH, Lee KH, Moon JH, Park KH. Jaboticabin and flavonoids from the ripened fruit of Rubus coreanum. Food Sci. Biotechnol. 21:1081–1086 (2012)

    Article  CAS  Google Scholar 

  13. Lee YA, Lee MW. Tannins from Rubus coreanum. Korean J. Pharm. 26: 27–30 (1995)

    CAS  Google Scholar 

  14. Lim JW, Jeong JT, Shin CS. Component analysis and sensory evaluation of Korean black raspberry (Rubus coreanus Miquel) wines. Int. J. Food Sci. Technol. 47: 918–926 (2012)

    Article  CAS  Google Scholar 

  15. Kwon KH, Cha WS, Kim DC, Shin HJ. A research and application of active ingredients in bokbunja (Rubus coreanus Miquel). Korean J. Biotechnol. Bioeng. 21: 405–409 (2006)

    Google Scholar 

  16. Jung JW, Son MY, Jung SW, Nam PW, Sung JS, Lee SJ, Lee KG. Antioxidant properties of Korean black raspberry wines and their apoptotic effects on cancer cell. J. Sci. Food Agr. 89: 970–977 (2009)

    Article  CAS  Google Scholar 

  17. Kim SJ, Lee HJ, Park KH, Rhee CO, Lim IJ, Chung HJ, Moon JH. Isolation and identification of low molecular phenolic antioxidants from ethylacetate layer of Korean black raspberry (Rubus coreanus) wine. Korean J. Food Sci. Technol. 40: 129–134 (2008)

    Google Scholar 

  18. Cho JY, Kim SJ, Lee HJ, Kim JY, Lym IJ, Kang SK, Park KH, Moon JH. Isolation and identification of low molecular volatile compounds form ethyl acetate layer of Korean black raspberry (Rubus coreanus Miq.) wine. Korean J. Food Sci. Technol. 43: 558–563 (2011)

    Google Scholar 

  19. Singleton VL, Rossi JA. Colorimetry of total phenolics with phospomolybdic-phosphotungstic acid reagents. Am. J. Enol. Viti. 16: 114–158 (1965)

    Google Scholar 

  20. Cliff MA, King MC, Schlosser J. Anthocaynin, phenolic composition, colour measurement and sensory analysis of BC commercial red wines. Food Res. Int. 40: 92–100 (2007)

    Article  CAS  Google Scholar 

  21. Yamaguchi T, Takamura H, Matobam T, Terao J. HPLC method for evaluation of the free radical-scavenging activity of food by using 1,1-diphenyl-2-picrylhydrazyl. Biosci. Biotechnol. Bioch. 62: 1201–1204 (1998)

    Article  CAS  Google Scholar 

  22. Murase H, Moon JH, Yamaguchi R, Kato K, Kunieda T, Yoshikawa T, Terao J. Antioxidant activity of a novel vitamin E derivative, 2-(α-D-glcuopyranosyl)methyl-2,5,7,8-tetramethylchroman-6-ol. Free Rad. Biol. Med. 24: 217–225 (1998)

    Article  CAS  Google Scholar 

  23. Arai H, Terao J, Abdalla DSP, Suzuki T, Takama K. Coulometric detection in high-performance liquid chromatographic analysis of cholesteryl ester hydroperoxides. Free Rad. Biol. Med. 20: 365–371 (1996)

    Article  CAS  Google Scholar 

  24. Puértolas E, Álvarez I, Raso, J. Changes in phenolic compounds of Aragón red wines during alcoholic fermentation. Food Sci. Technol. Int. 17: 77–86 (2011)

    Article  Google Scholar 

  25. Tian RR, Pan QH, Zhan JC, Li JM, Wan SB, Zhang QH, Huang WD. Comparison of phenolic acids and flavan-3-ols during wine fermentation of grapes with different harvest times. Molecules 14: 827–838 (2009)

    Article  CAS  Google Scholar 

  26. Ozela EF, Stringheta PC, Chauca MC. Stability of anthocyanin in spinach wine (Basella rubra) fruits. Cien. Invest. Agr. 34: 115–120 (2007)

    Google Scholar 

  27. Woodward G, Kroon P, Cassidy A, Kay C. Anthocyanin stability and recovery: Implications for the analysis of clinical and experimental samples. J. Agr. Food Chem. 57: 5271–5278 (2009)

    Article  CAS  Google Scholar 

  28. Lee SJ, Ahn B. Changes in physiochemical characteristics of black raspberry wines from different regions during fermentation. Korean J. Food Sci. Technol. 41: 662–667 (2009)

    Google Scholar 

  29. Choi HS, Kim MK, Park HS, Kim YS, Shin DH. Alcoholic fermentation of bobunja (Rubus coreanus Miq.) wine. Korean J. Food Sci. Technol. 38: 543–547 (2006)

    Google Scholar 

  30. Rice-Evans CA, Miller NJ, Paganga G. Structure-antioxidant activity relationships of flavonoids and phenolic acids. Free Rad. Biol. Med. 20: 933–956 (2006)

    Article  Google Scholar 

  31. Kim JY, Cho JY, Ma YK, Park KY, Lee SH, Ham KS, Lee HJ, Park KH, Moon JH. Dicaffeoylquinic acid derivatives and flavonoid glucosides from glasswort (Salicornia herbacea L.) and their antioxidative activity. Food Chem. 125: 55–62 (2011)

    Article  CAS  Google Scholar 

  32. Williams RJ, Spencer JPE, Rice-Evans C. Flavonoids: Antioxidants or signaling molecules. Free Rad. Biol. Med. 36: 838–849 (2004)

    Article  CAS  Google Scholar 

  33. Han XZ, Shen T, Lou HX. Dietary polyphenols and their biological significance. Int. J. Mol. Sci. 8: 950–988 (2007)

    Article  CAS  Google Scholar 

  34. Sangtagelo C, Varì R, Scazzochio BD, Benedetto R, Filesi C, Masella R. Polyphenols, intracellular signaling and inflammation. Ann. Ist. Super. Sanita 43: 394–405 (2007)

    Google Scholar 

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Correspondence to Jae-Hak Moon.

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Cho, JY., Jeong, J.H., Kim, J.Y. et al. Change in the content of phenolic compounds and antioxidant activity during manufacturing of black raspberry (Rubus coreanus Miq.) wine. Food Sci Biotechnol 22, 1–8 (2013). https://doi.org/10.1007/s10068-013-0207-5

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  • DOI: https://doi.org/10.1007/s10068-013-0207-5

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