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Biodegradable porous scaffolds for tissue engineering

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Abstract

 Three-dimensional scaffolds play an important role in tissue engineering as an adhesive substrate for implanted cells and a physical support to guide the formation of new organs. The scaffolds should facilitate cell adhesion, promote cell growth, allow the retention of differentiated cell functions, and be biocompatible, biodegradable, highly porous with a large surface-to-volume ratio, mechanically strong, and malleable. A number of biodegradable three-dimensional scaffolds have been developed for tissue engineering. This paper reviews some of the recent events in the development of these scaffolds.

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Authors and Affiliations

  1. Biomedical Engineering Laboratory, Graduate School of Engineering, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan Tel. +81-3-5841-6372; Fax +81-3-5841-6372 e-mail: tateishi@ingram.t.u-tokyo.ac.jp, , , , , , JP

    T. Tateishi & T. Ushida

  2. Tissue Engineering Research Center, National Institute of Advanced Industrial Science and Technology, Tsukuba, Japan, , , , , , JP

    G. Chen

Authors
  1. T. Tateishi
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  2. G. Chen
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  3. T. Ushida
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Received: March 6, 2002

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Tateishi, T., Chen, G. & Ushida, T. Biodegradable porous scaffolds for tissue engineering. J Artif Organs 5, 77–83 (2002). https://doi.org/10.1007/s100470200014

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  • DOI: https://doi.org/10.1007/s100470200014

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