Skip to main content
SpringerLink
Log in

Adenomyomatosis of the Gallbladder in Childhood: Report of a Case and Review of the Literature

  • Case Report
  • Published:
Pediatric and Developmental Pathology

ABSTRACT

Adenomyomatosis of the gallbladder is considered an acquired pathologic condition that affects adults, with only 2 cases previously described in childhood. We report on a 5-year-old boy with incidental detection of this lesion by ultrasonography. Pathologic and clinical assessments are discussed in addition to treatment decision-making, including current insights into the relation between adenomyomatosis and malignancy of the gallbladder. The liberal use of ultrasonography in children with abdominal pain may result in detection of an increasing number of asymptomatic patients. Caregivers should be aware of this condition and its therapeutic implications in the pediatric population.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Figure 1
Figure 2

Similar content being viewed by others

References

  1. Jutras JA. Hyperplastic cholecystoses. Hickey lecture, 1960. AJR Radium Ther Nucl Med 1960;83:795–827

    CAS  Google Scholar 

  2. Ram MD, Midha D. Adenomyomatosis of the gallbladder. Surgery 1975;78:224–229

    PubMed  CAS  Google Scholar 

  3. Meguid MM, Aun F, Bradford ML. Adenomyomatosis of the gallbladder. Am J Surg 1984;147:260–262

    Article  PubMed  CAS  Google Scholar 

  4. Ootani T, Shirai Y, Tsukada K, Muto T. Relationship between gallbladder carcinoma and the segmental type of adenomyomatosis of the gallbladder. Cancer 1992;69:2647–2652

    PubMed  CAS  Google Scholar 

  5. Alberti D, Callea F, Camoni G, et al. Adenomyomatosis of the gallbladder in childhood. J Ped Surg 1998;33:1411–1412

    Article  CAS  Google Scholar 

  6. Cetinkursun S, Surer I, Deveci S, et al. Adenomyomatosis of the gallbladder in a child. Dig Dis Sci 2003;48:733–736

    Article  PubMed  Google Scholar 

  7. Esper E, Kaufman DB, Crary GS, et al. Septate gallbladder with cholelithiasis: a cause of chronic abdominal pain in a 6-year-old child. J Pediatr Surg 1992;27:1560–1562

    Article  PubMed  CAS  Google Scholar 

  8. Nishimura A, Shirai Y, Hatakeyama. Segmental adenomyomatosis of the gallbladder predisposes to cholecystolithiasis. J Hepatobiliary Pancreat Surg 2004;11:342–347

    Article  PubMed  Google Scholar 

  9. Aldridge MC, Gruffaz F, Castaing D, Bismuth H. Adenomyomatosis of the gallbladder. A premalignant lesion? Surgery 1991;109:107–110

    PubMed  CAS  Google Scholar 

  10. Raghavendra BN, Subramanyam BR, Balthazar EJ, et al. Sonography of adenomyomatosis of the gallbladder: radiologic-pathologic correlation. Radiology 1983;146:747–752

    PubMed  CAS  Google Scholar 

  11. Hwang JI, Chou YH, Tsay SH, et al. Radiologic and pathologic correlation of adenomyomatosis of the gallbladder. Abdom Imaging 1998;23:73–77

    PubMed  CAS  Google Scholar 

  12. Yoshimitsu K, Honda H, Jimi M, et al. MR diagnosis of adenomyomatosis of the gallbladder and differentiation from gallbladder carcinoma: importance of showing Rokitansky-Aschoff sinuses. AJR 1999;172:1535–1540

    PubMed  CAS  Google Scholar 

  13. Yoshimitsu K, Honda H, Aibe H, et al. Radiologic diagnosis of adenomyomatosis of the gallbladder: comparative study among MRI, helical CT, and transabdominal US. J Comput Assist Tomogr 2001;25:843–850

    Article  PubMed  CAS  Google Scholar 

  14. Yoshimitsu K, Irie H, Aibe H, et al. Well-differentiated adenocarcinoma of the gallbladder with intratumoral cystic components due to abundant mucin production: a mimicker of adenomyomatosis. Eur Radiol 2005;15:229–233

    Article  PubMed  Google Scholar 

  15. Waldhausen JH, Benjamin DR. Cholecystectomy is becoming an increasingly common operation in children. Am J Surg 1999;177:364–367

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Pediatric Surgery Unit, University of Rome “La Sapienza”, Policlinico Umberto I, Viale Regina Elena, 324, 00161, Rome, Italy

    Augusto Zani, Maurizio Pacilli, Andrea Conforti, Alessandra Casati & Denis Andrew Cozzi

  2. Department of Experimental Medicine and Pathology, University of Rome “La Sapienza”, Policlinico Umberto I, Viale Regina Elena, 324, 00161, Rome, Italy

    Sandro Bosco

Authors
  1. Augusto Zani
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Maurizio Pacilli
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Andrea Conforti
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Alessandra Casati
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Sandro Bosco
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Denis Andrew Cozzi
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Denis Andrew Cozzi.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Zani, A., Pacilli, M., Conforti, A. et al. Adenomyomatosis of the Gallbladder in Childhood: Report of a Case and Review of the Literature. Pediatr Dev Pathol 8, 577–580 (2005). https://doi.org/10.1007/s10024-005-0074-z

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10024-005-0074-z

Keywords

Search

Navigation