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Psammomatoid juvenile ossifying fibroma: case study and a review

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Abstract

Background

The group of fibro-osseous lesions from the maxillofacial region is very heterogeneous, but what they all have in common is the substitution of normal bone by fibroblasts with the consequent formation of collagen fibers, as well as substitution by different types of mineralized tissues which may be similar to bone or cement. Within this group of lesions, the juvenile ossifying fibroma is found, considered a rare and recurrent benign fibro-osseous neoplasia. The term juvenile ossifying fibroma has been used in the literature to describe two histopathological variations of conventional ossifying fibroma. These variations are trabecular juvenile ossifying fibroma and psammomatoid juvenile ossifying fibroma. Psammomatoid juvenile ossifying fibroma is an uncommon bone-forming neoplasm with aggressive local growth. Diagnostic of this lesion occurs after the correlation of clinical, imaging, and histopathological findings. Proposed treatments range from enucleation and curettage to resection of the tumor.

Objectives

The present article has as its objectives to report an uncommon case of a 4-year-old male patient treated by conservative approach and revise the literature on juvenile ossifying fibroma.

Conclusions

Psammomatoid juvenile ossifying fibroma, for its being very uncommon, warrants further investigation in order to establish the best treatment, principally in children, with a view to minimizing mutilating treatments. In the case examined, a conservative treatment was chosen, where the surgeon established curette and cryotherapy, and the reintegration of the child in his social environment, without relapse during the first year of therapy.

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References

  1. Godt A, Gülicher D, Kalwitzki M, Kröber SM (2008) Dislocation of an upper third molar by an ossifying fibroma and case report. J Cranio-Maxillofac Surg 36:360–364

    Article  Google Scholar 

  2. Toro C, Millesi W, Zerman N, Robiony M, Politi M (2006) A case of aggressive ossifying fibroma with massive involvement in the mandible: differential diagnosis and management options. Int J Pediatr Otorhinolaryngol Extra 1:167–172

    Article  Google Scholar 

  3. Pinos AJSP, Gaya MVO, Sanchez EP, Capilla MV (2004) Juvenile ossifying fibroma: a case study. Med Oral Patol Oral Circ Bucal 9:454–458

    Google Scholar 

  4. El-Mofty S (2002) Psammomatoid and trabecular juvenile ossifying fibroma of the craniofacial skeleton: two distinct clinicopathologic entities. Oral Surg Oral Med Oral Pathol 9(3):296–304

    Article  Google Scholar 

  5. Slootweg PJ, Panders AK, Nikkels PGJ (1993) Psammomatoid ossifying fibroma of the paranasal sinuses. An extragnathic variant of cemento-ossifying fibroma. J Cranio-Maxillo-Facial Surg 21:294–297

    Article  CAS  Google Scholar 

  6. Leimola-Virtanen R, Vähätalo K, Syrjänen S (2001) Juvenile active ossifying fibroma of the mandible: a report on 2 cases. J Oral Maxillofacsurg 59:439–444

    Article  CAS  Google Scholar 

  7. Vaidya AM, Chow JM, Goldberg K, Stankiewicz JA (1998) Juvenile aggressive ossifying fibroma presenting itself as an ethmoid sinus mucocele. Otolaryngology Head and NeckSurgery 119(6):665–668

    Article  CAS  Google Scholar 

  8. Barnes L, Eveson JW, Reichart P, Sidransky D (eds) (2005) World health organization classification of tumours. Pathology and genetics of head and neck tumours. IARC Press, Lyon, pp 283–328

    Google Scholar 

  9. Reichart PA, Philipsen HP (1999) Tumores Odontogênicos. In: Reichart PA, Philipsen HP. Atlas Colorido de Odontologia-Patologia Bucal. 1. Ed. Artes Médicas São Paulo p. 245

  10. Smith SF, Newman L, Walker DM (2009) Juvenile aggressive psammomatoid ossifying fibroma: an interesting, challenging, and unusual case report and review of the literature. J Oral MaxillofacSurg 67:200–206

    Article  Google Scholar 

  11. Dominguete PR, Meyer TN, Alves FA, Bittencourt WS (2008) Juvenile ossifying fibroma of the jaw. British J Oral MaxillofacSurg 46:480–481

    Article  Google Scholar 

  12. Maaita JK (2000) Oral tumors in children: a review. J Clin Pediatr Dent 24:133–135

    CAS  PubMed  Google Scholar 

  13. Rinaggio J, Land M, Cleveland DB (2003) Juvenile ossifying fibroma of the mandible. J Pediatr Surg 38:648–650

    Article  PubMed  Google Scholar 

  14. Williams HK, Mangham C, Speight PM (2000) Juvenile ossifying fibroma. An analysis of eight cases and a comparison with other fibro-osseous lesions. J Oral Pathol Med 29:13–18

    Article  CAS  PubMed  Google Scholar 

  15. Johnson LC, Yousefi M, Vinh TN et al (1991) Juvenile active ossifying fibroma: its nature, dynamics and origin. Acta Otolaryngol Suppl 448:1

    Google Scholar 

  16. Waldron CA (1993) Fibro-osseous lesions of the jaws. J Oral MaxillofacSurg 51:828–835

    Article  CAS  Google Scholar 

  17. Aldred MJ, Talacko AA, Savarirayan R, Murdolo V, Mills AE, Radden BG et al (2006) Dental findings in a family with hyperparathyroidism–jaw tumor syndrome and a novel HRPT2 gene mutation. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 101:212–218

    Article  PubMed  Google Scholar 

  18. Granados R, Carrillo R, Nájera L, García-Villanueva M, Patrón M (2006) Psammomatoid ossifying fibromas: immunohistochemical analysis and differential diagnosis with psammomatousmeningiomas of craniofacial bones. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 101:614–619

    Article  PubMed  Google Scholar 

  19. Noudel R, Chauvet E, Cahn V, Mérol JC, Chays A, Rousseaux P (2009) Transcranial resection of a large sinonasal juvenile psammomatoid ossifying fibroma. Childs Nerv Syst 25(9):1115–1120

    Article  PubMed  Google Scholar 

  20. Brannon RB, Fowler CB (2001) Benign fibro-osseous lesions: a review of current concepts. Adv Anat Pathol 8:126–143

    Article  CAS  PubMed  Google Scholar 

  21. Slootweg PJ, Panders AK, Koopmans R, Nikkels PG (1994) Juvenile ossifying fibroma. An analysis of 33 cases with emphasis on histopathological aspects. J Oral Pathol Med 23:385–388

    Article  CAS  PubMed  Google Scholar 

  22. Espinosa SA, Villanueva J, Hampel H, Reyes D (2006) Spontaneous regeneration after juvenile ossifying fibroma resection: a case report. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 102:32–35

    Article  Google Scholar 

  23. Waldron CA, Osso Dd (2004) In: Neville BW, Damm DD, Allen CM, Bouquot JE (eds) Patologia Oral e Maxilofacial. Guanabara Koogan, Rio de Janeiro, pp 541–542

    Google Scholar 

  24. Zama M, Gallo S, Santecchia L (2004) Juvenile active ossifying fibroma with massive involvement of the mandible. Plast Reconstr Surg 113(3):970–974

    Article  PubMed  Google Scholar 

  25. Reaume CE, Schmid RW, Wesley RK (1985) Aggressive ossifying fibroma of the mandible. J Oral Maxillofac Surg 43:631–640

    Article  CAS  PubMed  Google Scholar 

  26. Slootweg PJ, Muller H (1990) Juvenile ossifying fibroma: report of four cases. J Craniomaxillofac Surg 18:125–131

    Article  CAS  PubMed  Google Scholar 

  27. Sun G, Chen X, Tang E, Li Z, Li J (2007) Juvenile ossifying fibroma of the maxilla. Int J Oral Maxillofac Surg 36:82–85

    Article  CAS  PubMed  Google Scholar 

  28. Cuellar AS, Granizo RM, De Pedro Marina M, Berguer A (1999) Fibroma cemento-osificante mandibular. Med Oral 4:504–506

    Google Scholar 

  29. Patil K, Mahima VG, Balaji P (2003) Juvenile aggressive cemento-ossifying fibroma. A case report. Indian J Dent Res 14:111–119

    CAS  PubMed  Google Scholar 

  30. Sarode SC, Sarode GS, Waknis P, Patil A, Jashika M (2011) Juvenile psammomatoid ossifying fibroma: a review. Oral Oncol 47(12):1110–1116

    Article  PubMed  Google Scholar 

  31. Papadaki ME, Troulis MJ, Kaban LB (2005) Advances in diagnosis and management of fibro-osseous lesions. Oral Maxillofacial Surg Clin N Am 17:415–434

    Article  Google Scholar 

  32. MacDonald-Jankowski DS (2004) Fibro-osseous lesions of the face and jaws. Clin Radiol 59(1):11–25

    Article  CAS  PubMed  Google Scholar 

  33. Khoury NJ, Naffaa LN, Shabb NS (2002) Juvenile ossifying fibroma: CT and MR findings. Eur Radiol 12:109–113

    Article  Google Scholar 

  34. Kaban LB, Troulis MJ, Ebb D, August M, Hornicek FJ, Dodson TB (2002) Antiangiogenic therapy with interferon alpha for giant cell lesions of the jaws. J Oral Maxillofac Surg 60:1103–1111

    Article  PubMed  Google Scholar 

  35. Partridgs JE, Hicks MJ, Marchena MJ (2007) A 7-year-old with progressive mandibular expansion. J Oral Maxillofac Surg 65:2047–2055

    Article  Google Scholar 

  36. Troulis MJ, Williams WB, Kaban LB (2004) Jaw tumors in children. In: Kaban LB, Troulis MJ (eds) Pediatric oral and maxillofacial surgery. Saunders, Philadelphia, p 225

    Google Scholar 

  37. Troulis MJ, Williams WB, Kaban LB (2004) Staged protocol for resection, skeletal reconstruction, and oral rehabilitation of children with jaw tumors. J Oral MaxillofacSurg 62:335–343

    Article  Google Scholar 

  38. Genden EM, Buchbinder D, Chaplin JM et al (2000) Reconstruction of the pediatric maxilla and mandible. Arch Otolaryngol Head Neck Surg 126:293

    Article  CAS  PubMed  Google Scholar 

  39. Tanaka N, Murata A, Yamaguchi A, Kohama G (1999) Clinical features and management of oral and maxillofacial tumors in children. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 88:11–15

    Article  CAS  PubMed  Google Scholar 

  40. Uckan S, Burak B, Kecik D, Araz K (2009) Effects of titanium plate fixation on mandibular growth in a rabbit model. J Oral MaxillofacSurg 67:318–322

    Article  Google Scholar 

  41. Rudolf RM (2005) Treatment of pediatric facial fractures: the case for metallic fixation. J Oral Maxillofac Surg 63:382–384

    Article  Google Scholar 

  42. Brahim JS (2005) Dental implants in children. Oral Maxillofacial SurgClin N Am 17:375–381

    Article  Google Scholar 

  43. Carmichae LR, Sándor GKB, Habil D (2008) Dental implants, growth of the jaws and determination of skeletal maturity. Atlas Oral Maxillofacial Surg Clin N Am 16:1–9

    Article  Google Scholar 

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Authors and Affiliations

  1. Department of Oral and Maxillofacial Surgery, Federal University of Bahia, Salvador, Bahia, Brazil

    Leonardo Morais Godoy Figueiredo

  2. Department of Oral Medicine, University of São Paulo, Bauru School of Dentistry, Bauru, São Paulo, Brazil

    Thaís Feitosa Leitão de Oliveira

  3. Department of Oral Medicine, Federal University of Bahia, Salvador, Bahia, Brazil

    Gardênia Matos Paraguassú

  4. Department of Oral and Maxillofacial Surgery, Institute of Integral Medicine, Recife, Pernambuco, Brazil

    Rômulo Oliveira de Hollanda Valente & Wilson Rodrigo Muniz da Costa

  5. Federal University of Bahia, Salvador, Bahia, Brazil

    Viviane Almeida Sarmento

Authors
  1. Leonardo Morais Godoy Figueiredo
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  2. Thaís Feitosa Leitão de Oliveira
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  3. Gardênia Matos Paraguassú
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  6. Viviane Almeida Sarmento
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Correspondence to Leonardo Morais Godoy Figueiredo.

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Figueiredo, L.M.G., de Oliveira, T.F.L., Paraguassú, G.M. et al. Psammomatoid juvenile ossifying fibroma: case study and a review. Oral Maxillofac Surg 18, 87–93 (2014). https://doi.org/10.1007/s10006-013-0400-y

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  • DOI: https://doi.org/10.1007/s10006-013-0400-y

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