Allen-Brady K, Miller J, Matsunami N, Stevens J, Block H, Farley M, Krasny L, Pingree C, Lainhart J, Leppert M, McMahon WM, Coon H (2008) A high-density SNP genome-wide linkage scan in a large autism extended pedigree. Mol Psychiatry, epub ahead of print
Aman MG, Farmer CA, Hollway J, Arnold LE (2008) Treatment of inattention, overactivity, and impulsiveness in autism spectrum disorders. Child Adolesc Psychiatr Clin N Am 17:713–738
Article
PubMed
Google Scholar
American Psychiatric Association (2000) Diagnostic and statistical manual of mental disorders, 4th edn, Text Revision. American Psychiatric Association, Washington, DC
Book
Google Scholar
Anckarsäter H, Stahlberg O, Larson T, Hakansson C, Jutblad SG, Niklasson L (2006) The impact of ADHD and autism spectrum disorders on temperament, character, and personality development. Am J Psychiatry 163:1239–1244
Article
PubMed
Google Scholar
Anderson BM, Schnetz-Boutaud N, Bartlett J, Wright HH, Abramson RK, Cuccaro ML, Gilbert JR, Pericak-Vance MA, Haines JL (2008) Examination of association to autism of common genetic variationin genes related to dopamine. Autism Res 1:364–369
Article
CAS
PubMed
Google Scholar
Angold A, Costello EJ, Erkanli A (1999) Comorbidity. J Child Psychol Psychiatry 40:57–87
Article
CAS
PubMed
Google Scholar
Asherson P, the IMAGE Consortium (2004) Attention-deficit hyperactivity disorder in the post-genomic area. Eur Child Adolesc Psychiatry 13:50–70
Article
Google Scholar
Autism Genome Project Consortium, Autism genome project consortium P, Paterson AD, Zwaigenbaum L, Roberts W, Brian J, Liu XQ, Vincent JB, Skaug JL, Thompson AP, Senman L, Feuk L, Qian C, Bryson SE, Jones MB, Marshall CR, Scherer SW, Vieland VJ, Bartlett C, Mangin LV, Goedken R, Segre A, Pericak-Vance MA, Cuccaro ML, Gilbert JR, Wright HH, Abramson RK, Betancur C, Bourgeron T, Gillberg C, Leboyer M, Buxbaum JD, Davis KL, Hollander E, Silverman JM, Hallmayer J, Lotspeich L, Sutcliffe JS, Haines JL, Folstein SE, Piven J, Wassink TH, Sheffield V, Geschwind DH, Bucan M, Brown WT, Cantor RM, Constantino JN, Gilliam TC, Herbert M, Lajonchere C, Ledbetter DH, Lese-Martin C, Miller J, Nelson S, Samango-Sprouse CA, Spence S, State M, Tanzi RE, Coon H, Dawson G, Devlin B, Estes A, Flodman P, Klei L, McMahon WM, Minshew N, Munson J, Korvatska E, Rodier PM, Schellenberg GD, Smith M, Spence MA, Stodgell C, Tepper PG, Wijsman EM, Yu CE, Rogé B, Mantoulan C, Wittemeyer K, Poustka A, Felder B, Klauck SM, Schuster C, Poustka F, Bölte S, Feineis-Matthews S, Herbrecht E, Schmötzer G, Tsiantis J, Papanikolaou K, Maestrini E, Bacchelli E, Blasi F, Carone S, Toma C, Van Engeland H, de Jonge M, Kemner C, Koop F, Langemeijer M, Hijmans C, Staal WG, Baird G, Bolton PF, Rutter ML, Weisblatt E, Green J, Aldred C, Wilkinson JA, Pickles A, Le Couteur A, Berney T, McConachie H, Bailey AJ, Francis K, Honeyman G, Hutchinson A, Parr JR, Wallace S, Monaco AP, Barnby G, Kobayashi K, Lamb JA, Sousa I, Sykes N, Cook EH, Guter SJ, Leventhal BL, Salt J, Lord C, Corsello C, Hus V, Weeks DE, Volkmar F, Tauber M, Fombonne E, Shih A, Meyer KJ (2007) Mapping autism risk loci using genetic linkage and chromosomal rearrangements. Nat Genet 39:319–328
Article
PubMed
CAS
Google Scholar
Bakker SC, van der Meulen EM, Buitelaar JK, Sandkuijl LA, Pauls DL, Monsuur AJ (2003) A whole-genome scan in 164 Dutch sib pairs with attention-deficit/hyperactivity disorder: suggestive evidence for linkage on chromosomes 7p and 15q. Am J Hum Genet 72:1251–1260
Article
CAS
PubMed
Google Scholar
Banaschewski T, Neale BM, Rothenberger A, Roessner V (2007) Comorbidity of tic disorders and ADHD—conceptual and methodological considerations. Eur Child Adolesc Psychiatry 16(suppl 1):i5–i14
Article
Google Scholar
Bearden CE, Freimer NB (2006) Endophenotypes for psychiatric disorders: ready for primetime? Trends Genet 22:306–313
Article
CAS
PubMed
Google Scholar
Becker K, El-Faddagh M, Schmidt MH, Esser G, Laucht M (2008) Interaction of dopamine transporter genotype with prenatal smoke exposure on ADHD symptoms. J Pediatr 152:263–269
Article
CAS
PubMed
Google Scholar
Benyamin B, Sørensen TI, Schousboe K, Fenger M, Visscher PM, Kyvik KO (2007) Are there common genetic and environmental factors behind the endophenotypes associated with the metabolic syndrome? Diabetologia 50:1880–1888
Article
CAS
PubMed
Google Scholar
Bethea TC, Sikich L (2007) Early pharmacological treatment of autism: a rationale for developmental treatment. Biol Psychiatry 61:521–537
Article
CAS
PubMed
Google Scholar
Biederman J, Newcorn J, Sprich S (1991) Comorbidity of attention deficit hyperactivity disorder with conduct, depressive, anxiety, and other disorders. Am J Psychiatry 148:564–577
CAS
PubMed
Google Scholar
Brookes K, Xu X, Chen W, Zhou K, Neale B, Lowe N, Anney R, Franke B, Gill M, Ebstein R, Buitelaar J, Sham P, Campbell D, Knight J, Andreou P, Altink M, Arnold R, Boer F, Buschgens C, Butler L, Christiansen H, Feldman L, Fleischman K, Fliers E, Howe-Forbes R, Goldfarb A, Heise A, Gabriëls I, Korn-Lubetzki I, Johansson L, Marco R, Medad S, Minderaa R, Mulas F, Müller U, Mulligan A, Rabin K, Rommelse N, Sethna V, Sorohan J, Uebel H, Psychogiou L, Weeks A, Barrett R, Craig I, Banaschewski T, Sonuga-Barke E, Eisenberg J, Kuntsi J, Manor I, McGuffin P, Miranda A, Oades RD, Plomin R, Roeyers H, Rothenberger A, Sergeant J, Steinhausen HC, Taylor E, Thompson M, Faraone SV, Asherson P (2006) The analysis of 51 genes in DSM-IV combined type attention deficit hyperactivity disorder: association signals in DRD4, DAT1 and 16 other genes. Mol Psychiatry 11:934–953
Article
CAS
PubMed
Google Scholar
Bucan M, Abrahams BS, Wang K, Glessner JT, Herman EI, Sonnenblick LI, Alvarez Retuerto AI, Imielinski M, Hadley D, Bradfield JP, Kim C, Gidaya NB, Lindquist I, Hutman T, Sigman M, Kustanovich V, Lajonchere CM, Singleton A, Kim J, Wassink TH, McMahon WM, Owley T, Sweeney JA, Coon H, Nurnberger JI, Li M, Cantor RM, Minshew NJ, Sutcliffe JS, Cook EH, Dawson G, Buxbaum JD, Grant SF, Schellenberg GD, Geschwind DH, Hakonarson H (2009) Genome-wide analyses of exonic copy number variants in a family-based study point to novel autism susceptibility genes. PLoS Genet 5:e1000536
Article
PubMed
CAS
Google Scholar
Buitelaar JK (2005) ADHD: strategies to unravel its genetic architecture. J Neural Transm Suppl 69:1–17
PubMed
Google Scholar
Caron C, Rutter M (1991) Comorbidity in child psychopathology: concepts, issues and research strategies. J Child Psychol Psychiatry 32:1063–1080
Article
CAS
PubMed
Google Scholar
Carpenter Rich E, Loo SK, Yang M, Dang J, Smalley SL (2009) Social functioning difficulties in ADHD: association with PDD risk. Clin Child Psychol Psychiatry 14:329–344
Article
PubMed
Google Scholar
Chin H, Choi SH, Jang YS, Cho SM, Kim HS, Lee JH, Jeong SW, Kim IK, Kim GJ, Kwon OJ (2006) Protein kinase A-dependent phosphorylation of B/K protein. Exp Mol Med 38:144–152
CAS
PubMed
Google Scholar
Christian SL, Brune CW, Sudi J, Kumar RA, Liu S, Karamohamed S, Badner JA, Matsui S, Conroy J, McQuaid D, Gergel J, Hatchwell E, Gilliam TC, Gershon ES, Nowak NJ, Dobyns WB, Cook EH Jr (2008) Novel submicroscopic chromosomal abnormalities detected in autism spectrum disorder. Biol Psychiatry 63:1111–1117
Article
CAS
PubMed
Google Scholar
Constantino JN, Hudziak JJ, Todd RD (2003) Deficits in reciprocal social behavior in male twins: evidence for a genetically independent domain of psychopathology. J Am Acad Child Adolesc Psychiatry 42:458–467
PubMed
Google Scholar
Craig IW (2007) The importance of stress and genetic variation in human aggression. BioEssays 29:227–236
Article
CAS
PubMed
Google Scholar
Das M, Bhowmik AD, Sinha S, Chattopadhyay A, Chaudhuri K, Singh M, Mukhopadhyay K (2006) MAOA promoter polymorphism and attention deficit hyperactivity disorder (ADHD) in Indian children. Am J Med Genet B Neuropsychiatr Genet 141:637–642
Google Scholar
Domschke K, Sheehan K, Lowe N, Kirley A, Mullins C, O’sullivan R, Freitag C, Becker T, Conroy J, Fitzgerald M, Gill M, Hawi Z (2005) Association analysis of the monoamine oxidase A and B genes with attention deficit hyperactivity disorder (ADHD) in an Irish sample: preferential transmission of the MAO-A 941G allele to affected children. Am J Med Genet B Neuropsychiatr Genet 134:110–114
Google Scholar
Duvall JA, Lu A, Cantor RM, Todd RD, Constantino JN, Geschwindt DH (2007) A quantitative trait locus analysis of social responsiveness in multiplex autism families. Am J Psychiatry 164:656–662
Article
PubMed
Google Scholar
Elia J, Gai X, Xie HM, Perin JC, Geiger E, Glessner JT, D’arcy M, Deberardinis R, Frackelton E, Kim C, Lantieri F, Muganga BM, Wang L, Takeda T, Rappaport EF, Grant SF, Berrettini W, Devoto M, Shaikh TH, Hakonarson H, White PS (2009) Rare structural variants found in attention-deficit hyperactivity disorder are preferentially associated with neurodevelopmental genes. Mol Psychiatry, epub ahead of print
Faraone SV, Perlis RH, Doyle AE, Smoller JW, Goralnick JJ, Holmgren MA, Sklar P (2005) Molecular genetics of attention-deficit/hyperactivity disorder. Biol Psychiatry 57:1313–1323
Article
CAS
PubMed
Google Scholar
Farzin F, Perry H, Hessl D, Loesch D, Cohen J, Bacalman S, Gane L, Tassone F, Hagerman P, Hagerman R (2006) Autism spectrum disorders and attention-deficit/hyperactivity disorder in boys with the fragile X permutation. J Dev Behav Pediatr 27:137–144
Article
Google Scholar
Franke B, Neale BM, Faraone SV (2009) Genome-wide association studies in ADHD. Hum Genet, epub ahead of print
Farzin F, Perry H, Hessl D, Loesch D, Cohen J, Bacalman S, Gane L, Tassone F, Hagerman P, Hagerman R (2001) Should the diagnosis of attention-deficit/hyperactivity disorder be considered in children with pervasive developmental disorder? J Atten Disord 4:203–211
Article
Google Scholar
Freitag CM (2007) The genetics of autistic disorders and its clinical relevance: a review of the literature. Mol Psychiatry 12:2–22
Article
CAS
PubMed
Google Scholar
Gadow KD, Roohi J, DeVincent CJ, Hatchwell E (2008) Association of ADHD, tics, and anxiety with dopamine transporter (DAT1) genotype in autism spectrum disorders. J Child Psychol Psychiatry 49:1331–1338
Article
PubMed
Google Scholar
Gadow KD, Roohi J, DeVincent CJ, Kirsch S, Hatchwell E (2009) Association of COMT (Val158Met) and BDNF (Val66Met) gene polymorphisms with anxiety, ADHD and tics in children with autism spectrum disorder. J Autism Dev Disord, epub ahead of print
Gillberg C, Gillberg IC, Rasmussen P, Kadesjö B, Söderström H, Råstam M, Johnson M, Rothenberger A, Niklasson L (2004) Co-existing disorders in ADHD—implications for diagnosis and intervention. Eur J Child Adolesc Psychiatry 13:80–92
Article
Google Scholar
Gizer IR, Ficks C, Waldman ID (2009) Candidate gene studies of ADHD: a meta-analytic review. Hum Genet, epub ahead of print
Glessner JT, Wang K, Cai G, Korvatska O, Kim CE, Wood S, Zhang H, Estes A, Brune CW, Bradfield JP, Imielinski M, Frackelton EC, Reichert J, Crawford EL, Munson J, Sleiman PM, Chiavacci R, Annaiah K, Thomas K, Hou C, Glaberson W, Flory J, Otieno F, Garris M, Soorya L, Klei L, Piven J, Meyer KJ, Anagnostou E, Sakurai T, Game RM, Rudd DS, Zurawiecki D, McDougle CJ, Davis LK, Miller J, Posey DJ, Michaels S, Kolevzon A, Silverman JM, Bernier R, Levy SE, Schultz RT, Dawson G, Owley T, McMahon WM, Wassink TH, Sweeney JA, Nurnberger JI, Coon H, Sutcliffe JS, Minshew NJ, Grant SF, Bucan M, Cook EH, Buxbaum JD, Devlin B, Schellenberg GD, Hakonarson H (2009) Autism genome-wide copy number variation reveals ubiquitin and neuronal genes. Nature 459:569–573
Article
CAS
PubMed
Google Scholar
Gould TD, Gottesman II (2006) Psychiatric endophenotypes and the development of valid animal models. Genes Brain Behav 5:113–119
Article
CAS
PubMed
Google Scholar
Grady DL, Harxhi A, Smith M, Flodman P, Spence MA, Swanson JM, Moyzis RK (2005) Sequence variants of the DRD4 gene in autism: further evidence that rare DRD4 7R haplotypes are ADHD specific. Am J Med Genet B Neuropsychiatr Genet 136B:33–35
Article
CAS
PubMed
Google Scholar
Guan L, Wang B, Chen Y, Yang L, Li J, Qian Q, Wang Z, Faraone SV, Wang Y (2009) A high-density single-nucleotide polymorphism screen of 23 candidate genes in attention deficit hyperactivity disorder: suggesting multiple susceptibility genes among Chinese Han population. Mol Psychiatry 14:546–554
Article
CAS
PubMed
Google Scholar
Handen BL, Johnson CR, Lubetsky M (2000) Efficacy of methylphenidate among children with autism and symptoms of attention-deficit hyperactivity disorder. J Aut Dev Disord 30:245–255
Article
CAS
Google Scholar
Hattori J, Ogino T, Abiru K, Nakano K, Oka M, Ohtsuka Y (2006) Are pervasive developmental disorders and attention-deficit/hyperactivity disorder distinct disorders? Brain Dev 28:371–374
Article
PubMed
Google Scholar
Hebebrand J, Dempfle A, Saar K, Thiele H, Herpertz-Dahlmann B, Linder M (2006) A genome-wide scan for attention-deficit/hyperactivity disorder in 155 German sib-pairs. Mol Psychiatry 11:196–205
Article
CAS
PubMed
Google Scholar
Heiser P, Friedel S, Dempfle A, Konrad K, Smidt J, Grabarkiewicz J (2004) Molecular genetic aspects of attention-deficit/hyperactivity disorder. Neurosci Biobehav Rev 28:625–641
Article
CAS
PubMed
Google Scholar
Hofvander B, Delorme R, Chaste P, Nydén A, Wentz E, Ståhlberg O, Herbrecht E, Stopin A, Anckarsäter H, Gillberg C, Råstam M, Leboyer M (2009) Psychiatric and psychosocial problems in adults with normal-intelligence autism spectrum disorders. BMC Psychiatry 9:35
Article
PubMed
Google Scholar
Holtman M, Bölte S, Pousta F (2007) Attention deficit hyperactivity disorder symptoms in pervasive developmental disorders: association with autistic behavior domains and coexisting psychopathology. Psychopathol 40:172–177
Article
Google Scholar
Huang CH, Santangelo SL (2008) Autism and serotonin transporter gene polymorphisms: a systematic review and meta-analysis. Am J Med Genet B Neuropsychiatr Genet 147B:903–913
Article
PubMed
Google Scholar
Jain M, Palacio LG, Castellanos FX, Palacio JD, Pineda D, Restrepo MI, Muñoz JF, Lopera F, Wallis D, Berg K, Bailey-Wilson JE, Arcos-Burgos M, Muenke M (2007) Attention-deficit/hyperactivity disorder and comorbid disruptive behavior disorders: evidence of pleiotropy and new susceptibility loci. Biol Psychiatry 61:1329–1339
Article
CAS
PubMed
Google Scholar
de Krom M, Staal WG, Ophoff RA, Hendriks J, Buitelaar J, Franke B, de Jonge MV, Bolton P, Collier D, Curran S, van Engeland H, van Ree JM (2009) A common variant in DRD3 receptor is associated with autism spectrum disorder. Biol Psychiatry 65:625–630
Article
PubMed
CAS
Google Scholar
Lee DO, Ousley OY (2006) Attention-deficit hyperactivity disorder symptoms in a clinic sample of children and adolescents with pervasive developmental disorders. J Child Adolesc Psychopharmacol 16:737–746
Article
CAS
PubMed
Google Scholar
Li D, Sham PC, Owen MJ, He L (2006) Meta-analysis shows significant association between dopamine system genes and attention deficit hyperactivity disorder (ADHD). Hum Mol Genet 15:2276–2284
Article
CAS
PubMed
Google Scholar
Liu J, Nyholt DR, Magnussen P, Parano E, Pavone P, Geschwind D, Lord C, Iversen P, Hoh J, Ott J, Gilliam TC (2001) A genomewide screen for autism susceptibility loci. Am J Hum Genet 69:327–340
Article
CAS
PubMed
Google Scholar
Ma D, Salyakina D, Jaworski JM, Konidari I, Whitehead PL, Andersen AN, Hoffman JD, Slifer SH, Hedges DJ, Cukier HN, Griswold AJ, McCauley JL, Beecham GW, Wright HH, Abramson RK, Martin ER, Hussman JP, Gilbert JR, Cuccaro ML, Haines JL, Pericak-Vance MA (2009) A genome-wide association study of autism reveals a common novel risk locus at 5p14.1. Ann Hum Genet 73:263–273
Article
CAS
PubMed
Google Scholar
Maher B (2008) Personal genomes: The case of the missing heritability. Nature 456:18–21
Article
CAS
PubMed
Google Scholar
Manor I, Tyano S, Mel E, Eisenberg J, Bachner-Melman R, Kotler M, Ebstein RP (2002) Family-based and association studies of monoamine oxidase A and attention deficit hyperactivity disorder (ADHD): preferential transmission of the long promotor-region repeat and its association with impaired performance on a continuous performance test (TOVA). Mol Psychiatry 7:626–632
Article
CAS
PubMed
Google Scholar
Marshall CR, Noor A, Vincent JB, Lionel AC, Feuk L, Skaug J, Shago M, Moessner R, Pinto D, Ren Y, Thiruvahindrapduram B, Fiebig A, Schreiber S, Friedman J, Ketelaars CE, Vos YJ, Ficicioglu C, Kirkpatrick S, Nicolson R, Sloman L, Summers A, Gibbons CA, Teebi A, Chitayat D, Weksberg R, Thompson A, Vardy C, Crosbie V, Luscombe S, Baatjes R, Zwaigenbaum L, Roberts W, Fernandez B, Autism genome project consortium P, Scherer SW (2008) Structural variation of chromosomes in autism spectrum disorder. Am J Hum Genet 82:477–488
Article
CAS
PubMed
Google Scholar
Mier D, Kirsch P, Meyer-Lindenberg A (2009) Neural substrates of pleiotropic action of genetic variation in COMT: a meta-analysis. Mol Psychiatry, epub ahead of print
Miller DT, Shen Y, Weiss LA, Korn J, Anselm I, Bridgemohan C, Cox GF, Dickinson H, Gentile J, Harris DJ, Hegde V, Hundley R, Khwaja O, Kothare S, Luedke C, Nasir R, Poduri A, Prasad K, Raffalli P, Reinhard A, Smith SE, Sobeih MM, Soul JS, Stoler J, Takeoka M, Tan WH, Thakuria J, Wolff R, Yusupov R, Gusella JF, Daly MJ, Wu BL (2009) Microdeletion/duplication at 15q13.2q13.3 among individuals with features of autism and other neuropsychiatric disorders. J Med Genet 46:242–248
Article
CAS
PubMed
Google Scholar
Muhle R, Trentacoste SV, Rapin I (2004) The genetics of autism. Pediatrics 113:e472–e486
Article
PubMed
Google Scholar
Mulligan A, Anney RJ, O’Regan M, Chen W, Butler L, Fitzgerald M, Buitelaar J, Steinhausen HC, Rothenberger A, Minderaa R, Nijmeijer J, Hoekstra PJ, Oades RD, Roeyers H, Buschgens C, Christiansen H, Franke B, Gabriels I, Hartman C, Kuntsi J, Marco R, Meidad S, Mueller U, Psychogiou L, Rommelse N, Thompson M, Uebel H, Banaschewski T, Ebstein R, Eisenberg J, Manor I, Miranda A, Mulas F, Sergeant J, Sonuga-Barke E, Asherson P, Faraone SV, Gill M (2009) Autism symptoms in attention-deficit/hyperactivity disorder: a familial trait which correlates with conduct, oppositional defiant, language and motor disorders. J Autism Dev Disord 39:197–209
Article
PubMed
Google Scholar
Munafò MR, Durrant C, Lewis G, Flint J (2009) Gene X environment interactions at the serotonin transporter locus. Biol Psychiatry 65:211–219
Article
PubMed
CAS
Google Scholar
Neale BM, Lasky-Su J, Anney R, Franke B, Zhou K, Maller JB (2008) Genome-wide association scan of attention deficit hyperactivity disorder. Am J Med Genet B Neuropsychiatr Genet 147B:1337–1344
Article
CAS
PubMed
Google Scholar
Nijmeijer JS, Hoekstra PJ, Minderaa RB, Buitelaar JK, Altink ME, Buschgens CJ, Fliers EA, Rommelse NN, Sergeant JA, Hartman CA (2008) PDD symptoms in ADHD, an independent familial trait? J Abnorm Child Psychol 37:443–453
Article
Google Scholar
Niklasson L, Rasmussen P, Oskarsdóttir S, Gillberg C (2009) Autism, ADHD, mental retardation and behavior problems in 100 individuals with 22q11 deletion syndrome. Res Dev Disabil 30:763–773
Article
PubMed
Google Scholar
Oades RD (2008) Dopamine-serotonin interactions in attention-deficit hyperactivity disorder (ADHD). Prog Brain Res 172:543–565
Article
CAS
PubMed
Google Scholar
Ogdie MN, Macphie IL, Minassian SL, Yang M, Fisher SE, Francks C, Cantor RM, McCracken JT, McGough JJ, Nelson SF, Monaco AP, Smalley SL (2003) A genomewide scan for attention-deficit/hyperactivity disorder in an extended sample: suggestive linkage on 17p11. Am J Hum Genet 72:1268–1279
Article
CAS
PubMed
Google Scholar
Pamplona FA, Pandolfo P, Savoldi R, Prediger RD, Takahashi RN (2009) Environmental enrichment improves cognitive deficits in spontaneously hypertensive rats (SHR): relevance for attention deficit/hyperactivity disorder (ADHD). Prog Neuropsychopharmacol Biol Psychiatry, epub ahead of print
Pickles A, Starr E, Kazak S, Bolton P, Papanikolaou K, Bailey A, Goodman R, Rutter M (2000) Variable expression of the autism broader phenotype: findings from extended pedigrees. J Child Psychol Psychiatry 41:491–502
Article
CAS
PubMed
Google Scholar
Posey DJ, Wiegand RE, Wilkerson J, Maynard M, Stigler KA, McDougle CJ (2006) Open-label atomoxetine for attention-deficit/hyperactivity disorder symptoms associated with high-functioning pervasive developmental disorders. J Child Adolesc Psychopharmacol 16:599–610
Article
PubMed
Google Scholar
Price GW, Michie PT, Johnston J, Innes-Brown H, Kent A, Clissa P, Jablensky AV (2006) A multivariate electrophysiological endophenotype, from a unitary cohort, shows greater research utility than any single feature in the Western Australian family study of schizophrenia. Biol Psychiatry 60:1–10
Article
PubMed
Google Scholar
Prince J (2008) Catecholamine dysfunction in attention-deficit/hyperactivity disorder: an update. J Clin Psychopharmacol 28:S39–S45
Article
CAS
PubMed
Google Scholar
Psychiatric GWAS Consortium Coordinating Committee (2009) Genomewide association studies: history, rationale, and prospects for psychiatric disorders. Am J Psychiatry 166:540–556
Article
Google Scholar
Psychiatric GWAS Consortium Steering Committee (2009) A framework for interpreting genome-wide association studies of psychiatric disorders. Mol Psychiatry 14:10–17
Article
CAS
Google Scholar
Reiersen AM, Constantino JN, Grimmer M, Martin NG, Todd RD (2008) Evidence for shared genetic influences on self-reported ADHD and autistic symptoms in young adult Australian twins. Twin Res Hum Genet 11:579–585
Article
PubMed
Google Scholar
Retz W, Rösler M, Supprian T, Retz-Junginger P, Thome J (2003) Dopamine D3 receptor gene polymorphism and violent behavior: relation to impulsiveness and ADHD-related psychopathology. J Neural Transm 110:561–572
Article
CAS
PubMed
Google Scholar
Romanos M, Freitag C, Jacob C, Craig DW, Dempfle A, Nguyen TT, Halperin R, Walitza S, Renner TJ, Seitz C, Romanos J, Palmason H, Reif A, Heine M, Windemuth-Kieselbach C, Vogler C, Sigmund J, Warnke A, Schäfer H, Meyer J, Stephan DA, Lesch KP (2008) Genome-wide linkage analysis of ADHD using high-density SNP arrays: novel loci at 5q13.1 and 14q12. Mol Psychiatry 13:522–530
Article
CAS
PubMed
Google Scholar
Rommelse NN, Arias-Vásquez A, Altink ME, Buschgens CJ, Fliers E, Asherson P, Faraone SV, Buitelaar JK, Sergeant JA, Oosterlaan J, Franke B (2008) Neuropsychological endophenotype approach to genome-wide linkage analysis identifies susceptibility loci for ADHD on 2q21.1 and 13q12.11. Am J Hum Genet 83:99–105
Article
CAS
PubMed
Google Scholar
Ronald A, Simonoff E, Kuntsi J, Asherson P, Plomin R (2008) Evidence for overlapping genetic influences on autistic and ADHD behaviours in a community twin sample. J Child Psychol Psychiatry 49:535–542
Article
PubMed
Google Scholar
Roohi J, DeVincent CJ, Hatchwell E, Gadow KD (2009) Association of a monoamine oxidase-A gene promoter polymorphism with ADHD and anxiety in boys with autism spectrum disorder. J Autism Dev Disord 39:67–74
Article
PubMed
Google Scholar
Rowlandson PH, Smith C (2009) An interagency service delivery model for autistic spectrum disorders and attention deficit hyperactivity disorder. Child Care Health Dev, epub ahead of print
Sabb FW, Burggren AC, Higier RG, Fox J, He J, Parker DS, Poldrack RA, Chu W, Cannon TD, Freimer NB, Bilder RM (2009) Challenges in phenotype definition in the whole-genome era: multivariate models of memory and intelligence. Neuroscience, epub ahead of print
Santosh PJ, Baird G, Pityaratstian N, Tavare E, Gringras P (2006) Impact of comorbid autism spectrum disorders on stimulant response in children with attention deficit hyperactivity disorder: a retrospective and prospective effectiveness study. Child Care Health Dev 32:575–583
Article
CAS
PubMed
Google Scholar
Schellenberg GD, Dawson G, Sung YJ, Estes A, Munson J, Rosenthal E, Rothstein J, Flodman P, Smith M, Coon H, Leong L, Yu CE, Stodgell C, Rodier PM, Spence MA, Minshew N, McMahon WM, Wijsman EM (2006) Evidence for multiple loci from a genome scan of autism kindreds. Mol Psychiatry 11:1049–1060
Article
CAS
PubMed
Google Scholar
Sebat J, Lakshmi B, Malhotra D, Troge J, Lese-Martin C, Walsh T, Yamrom B, Yoon S, Krasnitz A, Kendall J, Leotta A, Pai D, Zhang R, Lee YH, Hicks J, Spence SJ, Lee AT, Puura K, Lehtimäki T, Ledbetter D, Gregersen PK, Bregman J, Sutcliffe JS, Jobanputra V, Chung W, Warburton D, King MC, Skuse D, Geschwind DH, Gilliam TC, Ye K, Wigler M (2007) Strong association of de novo copy number mutations with autism. Science 316:445–449
Article
CAS
PubMed
Google Scholar
Simonoff E, Pickles A, Charman T, Chandler S, Loucas T, Baird G (2008) Psychiatric disorders in children with autism spectrum disorders: prevalence, comorbidity, and associated factors in a population-derived sample. J Am Acad Child Adolesc Psychiatry 47:921–929
Article
PubMed
Google Scholar
Sinzig J, Lehmkuhl G (2007) What do we know about the serotonergic genetic heterogeneity in attention-deficit/hyperactivity and autistic disorders? Psychopathol 40:329–337
Article
CAS
Google Scholar
Sinzig J, Walter D, Doepfner M (2009) Attention deficit/hyperactivity disorder in children and adolescents with autism spectrum disorder. Symptom or syndrome? J Atten Disord, epub ahead of print
Smalley SL, Kustanovich V, Minassian SL, Stone JL, Ogdie MN, McGough JJ, McCracken JT, MacPhie IL, Francks C, Fisher SE, Cantor RM, Monaco AP, Nelson SF (2002) Genetic linkage of attention-deficit/hyperactivity disorder on chromosome 16p13, in a region implicated in autism. Am J Hum Genet 71:959–963
Article
PubMed
Google Scholar
Sonuga-Barke EJ, Oades RD, Psychogiou L, Chen W, Franke B, Buitelaar J (2009) Dopamine and serotonin transporter genotypes moderate sensitivity to maternal expressed emotion: the case of conduct and emotional problems in attention deficit/hyperactivity disorder. J Child Psychol Psychiatry, epub ahead of print
Steyaert JG, De la Marche W (2008) What’s new in autism? Eur J Pediatr 167:1091–1101
Article
PubMed
Google Scholar
Tartaglia N, Davis S, Hench A, Nimishakavi S, Beauregard R, Reynolds A, Fenton L, Albrecht L, Ross J, Visootsak J, Hansen R, Hagerman R (2008) A new look at XXYY syndrome: medical and psychological features. Am J Med Genet A 146A:1509–1522
Article
PubMed
Google Scholar
Trikalinos TA, Karvouni A, Zintzaras E, Ylisaukko-oja T, Peltonen L, Jarvela I, Ioannidis JP (2006) A heterogeneity-based genome search meta-analysis for autism spectrum disorders. Mol Psychiatry 11:29–36
Article
CAS
PubMed
Google Scholar
Tripp G, Wickens JR (2009) Neurobiology of ADHD. Neuropharmacology, epub ahead of print
Troost PW, Steenhuis MP, Tuynman-Qua HG, Kalverdijk LJ, Buitelaar JK, Minderaa RB, Hoekstra PJ (2006) Atomoxetine for attention-deficit/hyperactivity disorder symptoms in children with pervasive developmental disorders: a pilot study. J Child Adolesc Psychopharmacol 16:611–619
Article
PubMed
Google Scholar
Wang K, Zhang H, Ma D, Bucan M, Glessner JT, Abrahams BS, Salyakina D, Imielinski M, Bradfield JP, Sleiman PM, Kim CE, Hou C, Frackelton E, Chiavacci R, Takahashi N, Sakurai T, Rappaport E, Lajonchere CM, Munson J, Estes A, Korvatska O, Piven J, Sonnenblick LI, Alvarez Retuerto AI, Herman EI, Dong H, Hutman T, Sigman M, Ozonoff S, Klin A, Owley T, Sweeney JA, Brune CW, Cantor RM, Bernier R, Gilbert JR, Cuccaro ML, McMahon WM, Miller J, State MW, Wassink TH, Coon H, Levy SE, Schultz RT, Nurnberger JI, Haines JL, Sutcliffe JS, Cook EH, Minshew NJ, Buxbaum JD, Dawson G, Grant SF, Geschwind DH, Pericak-Vance MA, Schellenberg GD, Hakonarson H (2009) Common genetic variants on 5p14.1 associate with autism spectrum disorders. Nature 459:528–533
Article
CAS
PubMed
Google Scholar
Warren DM, Dyer TD, Peterson CP, Mahaney MC, Blangero J, Almasy L (2005) A comparison of univariate, bivariate, and trivariate whole-genome linkage screens of genetically correlated electrophysiological endophenotypes. BMC Genet 6(Suppl 1):S117
Article
PubMed
CAS
Google Scholar
Weiss LA, Shen Y, Korn JM, Arking DE, Miller DT, Fossdal R, Saemundsen E, Stefansson H, Ferreira MA, Green T, Platt OS, Ruderfer DM, Walsh CA, Altshuler D, Chakravarti A, Tanzi RE, Stefansson K, Santangelo SL, Gusella JF, Sklar P, Wu BL, Daly MJ, Consortium Autism (2008) Association between microdeletion and microduplication at 16p11.2 and autism. N Engl J Med 358:667–675
Article
CAS
PubMed
Google Scholar
Yonan AL, Alarcón M, Cheng R, Magnusson PK, Spence SJ, Palmer AA, Grunn A, Juo SH, Terwilliger JD, Liu J, Cantor RM, Geschwind DH, Gilliam TC (2003) A genomewide screen of 345 families for autism-susceptibility loci. Am J Hum Genet 73:886–897
Article
CAS
PubMed
Google Scholar
Yoshida Y, Uchiyama T (2004) The clinical necessity for assessing attention deficit/hyperactivity disorder (AD/HD) symptoms in children with high-functioning pervasive developmental disorder (PDD). Eur Child Adolesc Psychiatry 13:307–314
Article
PubMed
Google Scholar
Zhou K, Dempfle A, Arcos-Burgos M, Bakker SC, Banaschewski T, Biederman J (2008) Meta-analysis of genome-wide linkage scans of attention deficit hyperactivity disorder. Am J Med Genet B Neuropsychiatr Genet 147B:1392–1398
Article
CAS
PubMed
Google Scholar
van der Zwaag B, Franke L, Poot M, Hochstenbach R, Spierenburg HA, Vorstman JA, van Daalen E, de Jonge MV, Verbeek NE, Brilstra EH, van ‘t Slot R, Ophoff RA, van Es MA, Blauw HM, Veldink JH, Buizer-Voskamp JE, Beemer FA, van den Berg LH, Wijmenga C, van Amstel HK, van Engeland H, Burbach JP, Staal WG (2009) Gene-network analysis identifies susceptibility genes related to glycobiology in autism. PLoS One 4:e5324
Article
PubMed
CAS
Google Scholar