Abstract
Objectives
Radiographic evaluation of the third molar maturation is used to estimate dental age, especially in adolescence. This study aimed to assess the application of three age estimation methods (Cameriere’s third molar maturity index (I3M), Demirjian’s maturation stages, and The London Atlas) to determine whether an individual is 18 years or older (adult) or younger than 18 years (minor).
Materials and methods
The dental age was estimated using the I3M, Demirjian’s maturation stages, and The London Atlas methods on panoramic radiograms of a total of 500 Turkish individuals aged 14–22 years. A logistic model was derived with an individual’s adult or minor status as the dependent variable, and each method and sex as predictive variables. The adult status was determined using dental age estimation methods and the performance of these methods in differentiating adults from minors was evaluated. The three methods were compared case-wise for their accuracy in predicting adult status.
Results
Logistic regression analysis showed that sex and each estimation method were statistically significant in discriminating adults and minors (p < 0.05). In the case-wise comparison for estimate adulthood, both Demirjian’s stages and I3M methods tended to perform better than the London Atlas method, with this trend reaching statistical significance (p < 0.05).
Conclusions
Cameriere’s I3M and Demirjian’s development stages are useful methods for adult age assessment in the tested population.
Clinical relevance
In forensic medicine and legal practices, Cameriere’s I3M and Demirjian’s maturation stage methods based on the development of the third molar teeth can be used to determine whether an individual is a minor or an adult.
Similar content being viewed by others
References
Urzel V, Bruzek J (2013) Dental age assessment in children: a comparison of four methods in a recent French population. J Forensic Sci 58(5):1341–1347. https://doi.org/10.1111/1556-4029.12221
McCloe D, Marion I, da Fonseca MA, Colvard M, AlQahtani S (2018) Age estimation of Hispanic children using the London Atlas. Forensic Sci Int 288:332.e1-332.e6. https://doi.org/10.1016/j.forsciint.2018.04.013
Focardi M, Pinchi V, De Luca F, Norelli GA (2014) Age estimation for forensic purposes in Italy: ethical issues. Int J Legal Med 128(3):515–522. https://doi.org/10.1007/s00414-014-0986-0
Corradi F, Pinchi V, Barsanti I, Manca R, Garatti S (2013) Optimal age classification of young individuals based on dental evidence in civil and criminal proceedings. Int J Legal Med 127(6):1157–1164. https://doi.org/10.1007/s00414-013-0919-3
Thevissen PW, Kvaal SI, Willems G (2012) Ethics in age estimation of unaccompanied minors. J Forensic Odontostomatol, 30 Suppl 1:84–102. Published 2012 Nov 30.
Schmeling A, Reisinger W, Geserick G, Olze A (2006). Age estimation of unaccompanied minors. Part I. General considerations. Forensic Sci Int, 15;159 Suppl 1:S61–4. doi: https://doi.org/10.1016/j.forsciint.2006.02.017. Epub 2006 Mar 9. PMID: 16529895.
Gelbrich B, Carl C, Gelbrich G (2019) Comparison of three methods to estimate dental age in children. Clinical Oral Investigations, 1–7.
Schmeling A, Olze A, Reisinger W, Geserick G (2004) Forensic age diagnostics of living people undergoing criminal proceedings. Forensic Sci Int, Sep 10;144(2–3):243–5. doi: https://doi.org/10.1016/j.forsciint.2004.04.059. PMID: 15364396.
Martin-de las Heras S, García-Fortea P, Ortega A, Zodocovich S, Valenzuela A (2008) Third molar development according to chronological age in populations from Spanish and Magrebian origin. Forensic Sci Int, Jan 15;174(1):47–53. https://doi.org/10.1016/j.forsciint.2007.03.009. Epub 2007 Apr 24. PMID: 17459627.
Cameriere R, Ferrante L, Cingolani M (2006) Age estimation in children by measurement of open apices in teeth. Int J Legal Med. Jan;120(1):49–52. doi: https://doi.org/10.1007/s00414-005-0047-9. Epub 2005 Nov 10. PMID: 16283352.
Black SA, Payne-James JB, Aggrawal AC (2010) Age Estimation in the Living. Wiley, New York
Kullman L, Johanson G, Akesson L (1992) Root development of the lower third molar and its relation to chronological age. Swed Dent J 16(4):161–167 (PMID: 1455327)
Mohd Yusof MY, Cauwels R, Deschepper E, Martens L (2015) Application of third molar development and eruption models in estimating dental age in Malay sub-adults. J Forensic Leg Med, Aug;34:40–4. doi: https://doi.org/10.1016/j.jflm.2015.05.004. Epub 2015 May 27. PMID: 26165657.
Correia AM, Barbosa DDS, Alcantara JADS, Oliveira PMDC, Silva PGB, Franco A, Bezerra TP (2020) Performance and comparison of the London Atlas technique and Cameriere’s third molar maturity index (I3M) for allocating individuals below or above the threshold of 18 years. Forensic Sci Int, Dec;317:110512. doi: https://doi.org/10.1016/j.forsciint.2020.110512. Epub 2020 Sep 17. PMID: 33002654.
Mincer HH, Harris EF, Berryman HE (1993) The A.B.F.O. study of third molar development and its use as an estimator of chronological age. J Forensic Sci. 1993 Mar;38(2):379–90. Erratum in: J Forensic Sci Nov;38(6):1524. PMID: 8454998.
Costa J, Montero J, Serrano S, Albaladejo A, López-Valverde A, Bica I (2014) Accuracy in the legal age estimation according to the third molars mineralization among Mexicans and Columbians. Aten Primaria. Nov;46 Suppl 5(Suppl 5):165–75. doi: https://doi.org/10.1016/S0212-6567(14)70086-1. PMID: 25476056; PMCID: PMC8171475.
Cameriere R, Ferrante L, De Angelis D, Scarpino F, Galli F (2008) The comparison between measurement of open apices of third molars and Demirjian stages to test chronological age of over 18 year olds in living subjects. Int J Legal Med, Nov;122(6):493–7. doi: https://doi.org/10.1007/s00414-008-0279-6. Epub 2008 Aug 28. PMID: 18751992.
Demirjian A, Goldstein H, Tanner JM (1973) A new system of dental age assessment. Hum Biol 45(2):211–227
Demirjian A, Goldstein H (1976) New systems for dental maturity based on seven and four teeth. Ann Hum Biol. Sep;3(5):411–21. doi: https://doi.org/10.1080/03014467600001671. PMID: 984727.
Alqahtani SJ, Hector MP, Liversidge HM (2010) Brief communication: the London atlas of human tooth development and eruption. Am J Phys Anthropol 142:481–490
Lewis JM, Senn DR (2010) Dental age estimation utilizing third molar development: a review of principles, methods, and population studies used in the United States. Forensic Sci Int. Sep 10;201(1–3):79–83. doi: https://doi.org/10.1016/j.forsciint.2010.04.042. Epub 2010 May 20. PMID: 20493649.
von Elm E, Altman DG, Egger M, Pocock SJ, Gøtzsche PC, Vandenbroucke JP; STROBE Initiative (2008) The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies. J Clin Epidemiol, Apr;61(4):344–9. doi: https://doi.org/10.1016/j.jclinepi.2007.11.008. PMID: 18313558.
Gulsahi A, De Luca S, Cehreli SB, Tirali RE, Cameriere R (2016) Accuracy of the third molar index for assessing the legal majority of 18 years in Turkish population. Forensic science international, 266, 584-e1- 584.e6.
Lizarbe RJQ, Adrianzén CS, Quezada-Márquez MM, Galić I, Cameriere R (2017) Demirjian’s stages and Cameriere’s third molar maturity index to estimate legal adult age in Peruvian population. Leg Med 25:59–65
Ferrante L, Skrami E, Gesuita R, Cameriere R (2015) Bayesian calibration for forensic age estimation. Stat Med 34:1779–1790
Ghafari R, Ghodousi A, Poordavar E (2019) Comparison of the accuracy of the London atlas and Smith method in dental age estimation in 5–15.99-year-old Iranians using the panoramic view. Int J Legal Med. Jan;133(1):189–195. doi: https://doi.org/10.1007/s00414-018-1808-6. Epub 2018 Mar 7. PMID: 29516249.
Brkic H, Milicevic M, Petrovecki M (2006) Age estimation methods using anthropological parameters on human teeth. Forensic Sci Int 162:13–16
Braga J, Heuze Y, Chabadel O, Sonan NK, Gueramy A (2005) Non-Adult dental age assessment: correspondence analysis and linear regression versus bayesian predictions. Int J Legal Med 119:260–274
Liversidge HM, Marsden PH (2010) Estimating age and the likelihood of having attained 18 years of age using mandibular third molars. Br Dent J, Oct 23;209(8):E13. doi: https://doi.org/10.1038/sj.bdj.2010.976. Epub 2010 Oct 15. PMID: 20953166.
Bassed RB, Briggs C, Drummer OH (2011) Age estimation and the developing third molar tooth: an analysis of an australian population using computed tomography. J Forensic Sci 56:1185–1191
Meinl A, Tangl S, Huber C et al (2007) The chronology of third molar mineralization in the Austrian population-a contribution to forensic age estimation. Forensic Sci Int 169:161–167
Karataş OH, Öztürk F, Dedeoğlu N, et al. (2013) Radiographic evaluation of third-molar development in relation to the chronological age of Turkish children in the southwest eastern Anatolia region. Forensic Sci Int, 232:238.1–5
Ribier L, Saint-Martin P, Seignier M, Paré A, Brunereau L, Rérolle C (2020) Cameriere’s third molar maturity index in assessing age of majority: a study of a French sample. Int J Legal Med 134(2):783–792. https://doi.org/10.1007/s00414-019-02123-z
Rolseth V, Mosdøl A, Dahlberg PS et al (2019) Age assessment by Demirjian’s development stages of the third molar: a systematic review. Eur Radiol 29(5):2311–2321. https://doi.org/10.1007/s00330-018-5761-z
Sisman Y, Uysal T, Yagmur F, Ramoglu SI (2007) Third-molar development in relation to chronologic age in Turkish children and young adults. Angle Orthod, Nov;77(6):1040–5. doi: https://doi.org/10.2319/101906-430.1. PMID: 18004924.
Dhanjal KS, Bhardwaj MK, Liversidge HM (2006) Reproducibility of radiographic stage assessment of third-molars. Forensic Sci Int 159:74–77
Cantekin K, Yilmaz Y, Demirci T, Celikoglu M (2012) Morphologic analysis of third-molar mineralization for eastern Turkish children and youth. J Forensic Sci, Mar;57(2):531–4.
Orhan K, Ozer L, Orhan AI, Dogan S, Paksoy CS (2007) Radiographic evaluation of third molar development in relation to chronological age among Turkish children and youth. Forensic Sci Int, Jan 5;165(1):46–51.
Swets JA (1988) Measuring the accuracy of diagnostic systems. Science. Jun 3;240(4857):1285–93.
Kanchan T, Chugh V, Chugh A, Meshram V, Shedge R, Patnana AK, Krishan K (2021) Age estimation using third molar maturation based on Demirjian’s criteria. Leg Med (Tokyo) 53:101959. https://doi.org/10.1016/j.legalmed.2021.101959
AlQahtani S, Kawthar A, AlAraik A, AlShalan A (2017) Third molar cut-off value in assessing the legal age of 18 in Saudi population. Forensic Sci Int, Mar;272:64–67. doi: https://doi.org/10.1016/j.forsciint.2017.01.004. Epub 2017 Jan 11. PMID: 28122322.
Dardouri AAK, Cameriere R, De Luca S, Vanin S (2016) Third molar maturity index by measurements of open apices in a Libyan sample of living subjects. Forensic Sci Int, Oct;267:230.e1–230.e6. doi: https://doi.org/10.1016/j.forsciint.2016.07.020. Epub 2016 Aug 9. PMID: 27622753.
Franklin D, Karkhanis S, Flavel A, Collini F, DeLuca S, Cameriere R (2016) Accuracy of a cut-off value based on the third molar index: validation in an Australian population. Forensic Sci Int. Sep;266:575.e1–575.e6. doi: https://doi.org/10.1016/j.forsciint.2016.06.032. Epub 2016 Jun 28. PMID: 27427495.
Deitos AR, Costa C, Michel-Crosato E, Galić I, Cameriere R, Biazevic MG (2015) Age estimation among Brazilians: Younger or older than 18? J Forensic Leg Med, Jul;33:111–5. doi: https://doi.org/10.1016/j.jflm.2015.04.016. Epub 2015 May 9. PMID: 26048509.
Akkaya N, Yilanci HO (2021) Assessment of third molar maturity index for legal age threshold of 18 in a sample of Turkish individuals. Aust J Forensic Sci 53(3):314–324. https://doi.org/10.1080/00450618.2020.1729412
Sousa AMDS, Jacometti V, AlQahtani S, Silva RHAD (2020) Age estimation of Brazilian individuals using the London Atlas. Arch Oral Biol. May;113:104705. doi: https://doi.org/10.1016/j.archoralbio.2020.104705. Epub 2020 Mar 10. PMID: 32197132.
Nóbrega JBMD, Protasio APL, Ribeiro ILA, Valença AMG, Santiago BM, Cameriere R (2019) Validation of the Third Molar Maturation Index to estimate the age of criminal responsibility in Northeastern Brazil. Forensic Sci Int. Nov;304:109917. doi: https://doi.org/10.1016/j.forsciint.2019.109917. Epub 2019 Aug 7. PMID: 31421921.
Hassan FM, Moawad AM, Samir W, Helaly YR, Abu-Taleb NS (2021) Mandibular third molar maturation stage as indicator for the legal adult age in an Egyptian sample. Homo 72(2):87–97. https://doi.org/10.1127/homo/2021/1344
Palmela Pereira C, Rodrigues A, Santos A, Salvado F, Santos R, Cameriere R (2021) Cut-off for the legal ages in the Portuguese Population by Third Maturity Index: Measures of Accuracy. Arch Oral Biol 125:105089. https://doi.org/10.1016/j.archoralbio.2021.105089
Çelikoglu M, Miloglu O, Kazanci F (2010) Frequency of agenesis, impaction, angulation, and related pathologic changes of third molar teeth in orthodontic patients. J Oral Maxillofac Surg 68(5):990–995. https://doi.org/10.1016/j.joms.2009.07.063
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Ethics approval
Ethical approval was obtained from the Ethical Committee of Alanya Alaaddin Keykubat University, Antalya, Turkey (approval number: 2020/22–37). All procedures followed were by the ethical standards of the responsible committee on human experimentation (institutional and national) and with the Helsinki Declaration of 1975, as revised in 2008.
Informed consent
Patients were not exposed to any additional radiation for this study, but informed consent was obtained from the patients’ parents for their data to be used for scientific purposes.
Conflict of interest
The authors declare no competing interests.
Additional information
Publisher's note
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Rights and permissions
About this article
Cite this article
Akman, H., Surme, K., Cimen, T. et al. Accuracy of different dental age estimation methods for determining the legal majority of 18 years in the Turkish population. Clin Oral Invest 26, 4537–4547 (2022). https://doi.org/10.1007/s00784-022-04417-w
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00784-022-04417-w