Abstract
Since the discovery in the 1950s that mammals have a nutritional requirement for chromium, the biological function of chromium has been sought. Candidates for the naturally-occurring biologically active form of chromium have been proposed, but, until recently, all have been shown to be artifacts. Recent studies examining the properties of the oligopeptide low-molecular-weight chromium-binding substance (LMWCr) suggest that this material may have a role in carbohydrate and lipid metabolism as part of a novel insulin-signaling amplification mechanism and may have implications in the treatment of diabetes and related conditions.
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Received: 24 March 1997 / Accepted: 9 September 1997
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Davis, C., Vincent, J. Chromium in carbohydrate and lipid metabolism. JBIC 2, 675–679 (1997). https://doi.org/10.1007/s007750050183
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DOI: https://doi.org/10.1007/s007750050183