Abstract
Quantitative nuclear magnetic resonance (QNMR) is a primary analytical method which allows the use of a standard not directly related to the target analyte. This could allow the introduction of a single universal reference material (URM) to which all other organic standard reference materials/certified reference materials may be compared. Dimethylsulfone is a simple substance that fulfils all criteria necessary as the URM to which the QNMR analysis of all other organic substances may be referenced and hence we propose this as a candidate for this purpose.
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Acknowledgements
We wish to thank Dr. G. Ball for fruitful discussions, Mrs H. Stender for expert assistance obtaining NMR spectra, Dr. L. Besley of the Australian National Measurement Laboratory for the measurements of DMSO2 by DSC and Prof. D.B. Hibbert for statistical advice.
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Wells, R.J., Cheung, J. & Hook, J.M. Dimethylsulfone as a universal standard for analysis of organics by QNMR. Accred Qual Assur 9, 450–456 (2004). https://doi.org/10.1007/s00769-004-0779-0
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DOI: https://doi.org/10.1007/s00769-004-0779-0