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Proficiency tests for pharmaceuticals in different waters

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Abstract.

To date there are no German or international standards for the analysis of pharmaceuticals in waters. The efficiency of the analytical methods—predominantly LC-MS/MS and GC-MS—used for trace analysis of pharmaceuticals is proved for the first time by proficiency tests using natural waters.

Two proficiency tests for up to 11 different groups of pharmaceuticals in river water and waste water were carried out in 2000 (28 participants) and 2002 (20 participants). The spiking concentrations were 60–800 ng/L for surface water and 80–1280 ng/L for waste water. For most determinants good recovery rates (80–120%) and variations (around 35% for surface water and 50% for waste water) were reported.

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Acknowledgement.

We thank Mrs. Renate Eisenmann for her careful technical assistance.

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Authors and Affiliations

  1. Bayerisches Landesamt für Wasserwirtschaft (Bavarian Water Management Agency) , Kaulbachstr. 37, 80539, Munich, Germany

    Manfred Sengl & Sonja Krezmer

Authors
  1. Manfred Sengl
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  2. Sonja Krezmer
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Correspondence to Manfred Sengl.

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Sengl, M., Krezmer, S. Proficiency tests for pharmaceuticals in different waters. Accred Qual Assur 8, 523–529 (2003). https://doi.org/10.1007/s00769-003-0688-7

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  • DOI: https://doi.org/10.1007/s00769-003-0688-7

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