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MRI of Inanimate Objects Using Fluorine-Containing Liquid

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Abstract

The paper shows the possibilities of using a fluorine-containing liquid—the so-called dry water for the MRI of inanimate objects using the signal void imaging method. Examples of visualization of objects that cannot be immersed in ordinary water and other liquid media that can dissolve or spoil the object under study are presented. The possibilities of visualization of a radio engineering product immersed in dry water during its operation are shown. Namely, the coil, which itself is involved in the scanning process, is used to receive and/or transmit RF power. It is shown that the images of the medium surrounding the coil obtained in this case make it possible to construct sensitivity maps and B1 maps of this coil. The issues of optimization of scanning parameters based on information about the 19F NMR spectrum and measurements of relaxation times for a given liquid are discussed.

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The datasets generated during and/or analyzed during the current study are available from the corresponding author on reasonable request.

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Acknowledgements

This research was supported by the Russian Foundation for Basic Research grants No. 19-29-10015 and Russian Scientific Foundation grant No. 21-75-10038, the Interdisciplinary Scientific and Educational Schools of Moscow University “Molecular Technologies of the Living Systems and Synthetic Biology” and “Photonic and quantum technologies. Digital medicine”. Access to electronic scientific resources was provided by Nesmeyanov Institute of Organoelement Compounds of the Russian Academy of Sciences with the support of the Ministry of Science and Higher Education of the Russian Federation.

Funding

This research was supported by the Russian Foundation for Basic Research grants No. 19-29-10015 and Russian Scientific Foundation grant No. 21–75-10038.

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Authors and Affiliations

  1. Faculty of Fundamental Medicine, Lomonosov Moscow State University, 119991, Moscow, Russian Federation

    Nikolay V. Anisimov

  2. Nesmeyanov Institute of Organoelement Compounds of the Russian Academy of Sciences, 119334, Moscow, Russian Federation

    Lev L. Gervits

  3. Faculty of Physics, Lomonosov Moscow State University, 119991, Moscow, Russian Federation

    Arina A. Tarasova, Ivan A. Usanov & Yury A. Pirogov

Authors
  1. Nikolay V. Anisimov
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  2. Lev L. Gervits
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  3. Arina A. Tarasova
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  4. Ivan A. Usanov
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  5. Yury A. Pirogov
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Contributions

NVA and YuAP wrote the main manuscript text; LLG prepared Fig. 1; AAT prepared Fig. 2 and IAU prepared Fig. 3. All authors reviewed the manuscript.

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Correspondence to Nikolay V. Anisimov.

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Anisimov, N.V., Gervits, L.L., Tarasova, A.A. et al. MRI of Inanimate Objects Using Fluorine-Containing Liquid. Appl Magn Reson 54, 895–904 (2023). https://doi.org/10.1007/s00723-023-01580-5

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  • DOI: https://doi.org/10.1007/s00723-023-01580-5

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