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Influence of Iodinated Contrast Media and Isotope 99mTc on Changes of Signal to Noise Ratio of Magnetic Resonance Imaging

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Abstract

The purpose of the study is to find out the changes of the signal-to-noise ratio (SNR) of magnetic resonance imaging (MRI) when performing MRI, computed tomography (CT), and isotope examination using 99mTc. For the study, divide the phantoms into two groups: (1) saline, saline + different kinds of contrast agent without 99mTc administration; (2) 99mTc administration: saline, saline + different kinds of the contrast agent with 99mTc administration. The CT contrast agent was used for Iopamidol® and Dotarem. And MRI contrast agent was used for Primovist® and Gadovist®. To obtain image, we used 3.0 T MR System, and obtained T1 and T2 images. Using obtained image, we compared an average value of SNR of T1 and T2 before and after distributing 99mTc. As a result, SNR in T1 images had a significant difference before and after putting 99mTc to every contrast media except normal saline. Also SNR in T2 mages had a significant difference before and after putting 99mTc in every contrast media except Gadovist®.

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Acknowledgments

This work was supported in part by the Soonchunhyang University Research Fund.

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    Authors and Affiliations

    1. Department of Radiology, Korea Veterans Hospital, Seoul, Republic of Korea

      Jin-Hyeok Lee

    2. Department of International Radiological Science, Hallym University of Graduate Studies, 427, Yeoksam-ro, Gangnam-gu, Seoul, 135-841, Republic of Korea

      Jin-Hyeok Lee & Jae-Hwan Cho

    3. Department of Computer Science and Engineering, Soonchunhyang University, Asan, Republic of Korea

      Hae-Kag Lee

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    1. Jin-Hyeok Lee
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    2. Hae-Kag Lee
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    3. Jae-Hwan Cho
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    Corresponding author

    Correspondence to Jae-Hwan Cho.

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    J.-H. Lee and H.-K. Lee equally contributed to this work. They are co-authors of first.

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    Lee, JH., Lee, HK. & Cho, JH. Influence of Iodinated Contrast Media and Isotope 99mTc on Changes of Signal to Noise Ratio of Magnetic Resonance Imaging. Appl Magn Reson 46, 931–940 (2015). https://doi.org/10.1007/s00723-015-0695-y

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    • DOI: https://doi.org/10.1007/s00723-015-0695-y

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