Abstract.
2,6-Dichloropurine ribonucleoside is a precursor in the potential synthesis of anticancer and antiviral drugs. 35Cl nuclear quadrupole resonance (NQR) studies on electronic structure and the character of C–Cl bonds may provide a valuable information about the difference in reactivity of chlorine atoms present in this compound. In this work 35Cl NQR frequencies, asymmetry parameters and double-bond character for both C–Cl bonds have been determined experimentally. These parameters were then compared with the corresponding theoretical values obtained by means of the density functional theory.
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Authors' address: Iwona Dobak, Department of Chemistry, Adam Mickiewicz University, Grunwaldska 6, Poznań 60-780, Poland
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Dobak, I., Ostafin, M., Poleshchuk, O. et al. Reactivity of 2,6-Dichloropurine Ribonucleoside Studied by 35Cl NQR Spectroscopy. Appl Magn Reson 34, 47–53 (2008). https://doi.org/10.1007/s00723-008-0091-y
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DOI: https://doi.org/10.1007/s00723-008-0091-y