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Quantitative Pupillometrie: Pupillenlichtreaktion im Kindes- und Jugendalter bei Links- und Rechtshändern im Seitenvergleich

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Summary

BACKGROUND: The pupil size and its reaction to light (pupillary light reflex [PLR]) have been referred to as the ideal indicators of autonomic functionality. This study was initiated to establish normative data of PLR parameters in the dark adapted eye in children. A special focus was to investigate the influence of handedness, the comparison of the reaction to light of the right vs. left eye and by the order of the tested side. METHODS: PLR was measured in 100 healthy children (50 left- and 50 right-hander) by infrared video pupillometry. Both eyes were measured in randomized order and PLR parameters were computed. RESULTS: The normative PLR data are presented. Regarding the first vs. second tested eye nearly all measured parameters showed significant differences. As to the handedness there are significant differences between left- and right hander for the left eye only. Only the left-handers showed significant differences in comparison to their left vs. right eye. CONCLUSION: The differences in PLR parameters between the first and the second measured eye are due to reflex facilitation. The left hander showed significant differences in PLR between the left and right eye. With regard to the theory of central lateralisation this suggests a parasympathetically-dominated left eye in left hander.

Zusammenfassung

GRUNDLAGEN: Der Pupillenlichtreflex (PLR) kann als idealer Indikator für die Funktion des autonomen Nervensystems angesehen werden. Ziel der vorliegenden Studie war es, Normwerte für PLR-Parameter für das Kindes- und Jugendalter am dunkeladaptierten Auge zu erstellen. Ein besonderes Augenmerk wurde dabei auf die Händigkeit, die Reihenfolge des gemessenen Auges sowie den Vergleich zwischen rechtem und linkem Auge gerichtet. METHODIK: Die PLR wurde bei 100 gesunden Probanden (50 Linkshänder, 50 Rechtshänder) mittels Infrarotvideo-Pupillographie standardisiert gemessen. Beide Augen wurden in randomisierter Reihenfolge untersucht und PLR-Parameter wurden am PC aufgezeichnet. ERGEBNISSE: Es werden Normwerte für PLR-Parameter vorgelegt. Bezüglich der Reihenfolge des untersuchten Auges ergaben sich signifikante Unterschiede für nahezu alle Parameter. Nur für das linke Auge ergaben sich signifikante Unterschiede zwischen Links- und Rechtshändern. Lediglich Linkshänder zeigten signifikante Unterschiede zwischen rechtem und linkem Auge. SCHLUSSFOLGERUNG: Unterschiede der PLR-Parameter bezüglich der Messreihenfolge der Pupille lassen sich mit Bahnungseffekten erklären. Die Theorie der Lateralisierung zentraler autonomer Funktionen legt ein parasympathisch dominiertes linkes Auge bei Linkshändern nahe.

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Authors and Affiliations

  1. Familienpraxis Oggersheim, Ludwigshafen, Germany

    S. Shazi & S. König

  2. Vendsyssel Krankenhaus, Kinderklinik, Hjoerring, Dänemark

    E. Longin

  3. Statistical Consulting, Mannheim, Germany

    T. Lenz

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  1. S. Shazi
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  2. T. Lenz
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  3. S. König
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  4. E. Longin
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Correspondence to S. Shazi.

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Shazi, S., Lenz, T., König, S. et al. Quantitative Pupillometrie: Pupillenlichtreaktion im Kindes- und Jugendalter bei Links- und Rechtshändern im Seitenvergleich. Spektrum Augenheilkd. 25, 19–28 (2011). https://doi.org/10.1007/s00717-011-0468-4

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  • DOI: https://doi.org/10.1007/s00717-011-0468-4

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