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Novel synthesis of dihydroquinoxaline, thiocyanatomaleate, uracil, pyridinium ylide, and S-aryl carbamimidothioate derivatives

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Abstract

The novel functionalized alkyl (Z)-2-(3-oxo-3,4-dihydroquinoxalin-2(1H)-ylidene)acetate, uracil, and thiocyanatomaleate derivatives have been prepared from substituted dihydroquinoxalines, benzylaminomaleates, and 6-amino-1,3-dimethylpyrimidine-2,4(1H,3H)-dione in the presence of N-thiocyanatosuccinimide intermediate generated from NH4SCN with NCS at room temperature, respectively. Convenient synthesis of sulfur-containing compounds of pyridinium ylide and S-aryl carbamimidothioate derivatives is described under catalyst-free condition in good yields.

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Acknowledgements

We thank the Bushehr Branch, Islamic Azad University for support.

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  1. Chemistry Department, Bushehr Branch, Islamic Azad University, PO Box 7519619555, Bushehr, Iran

    Ali Monfared & Gholamhossein Khalili

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  1. Ali Monfared
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  2. Gholamhossein Khalili
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Correspondence to Gholamhossein Khalili.

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Monfared, A., Khalili, G. Novel synthesis of dihydroquinoxaline, thiocyanatomaleate, uracil, pyridinium ylide, and S-aryl carbamimidothioate derivatives. Monatsh Chem 153, 1235–1241 (2022). https://doi.org/10.1007/s00706-022-02992-y

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  • DOI: https://doi.org/10.1007/s00706-022-02992-y

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