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One-pot and solvent-free synthesis of aliphatic and aromatic 1H-indazolo[2,1-b]phthalazinetriones catalyzed by boron sulfonic acid

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Abstract

An efficient and simple method for the synthesis of aliphatic and aromatic 1H-indazolo[2,1-b]phthalazinetrione derivatives through a one-pot three-component condensation of phthalhydrazide, aldehyde, and dimedone in the presence of boron sulfonic acid as a reusable and efficient catalyst under solvent-free conditions is described. The reusability of catalyst, good to excellent yields, short reaction times, and the avoidance of harsh reagents are the main advantages of this method.

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Acknowledgments

The authors gratefully acknowledge the Payame Noor University (PNU) of Ilam for partial support of this work.

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Authors and Affiliations

  1. School of Chemistry, College of Science, University of Tehran, P.O. Box 14155-6455, Tehran, Iran

    Mehdi Soheilizad & Mehdi Adib

  2. Department of Chemistry, Payame Noor University, P.O. Box 19395-4697, Tehran, Iran

    Sami Sajjadifar

Authors
  1. Mehdi Soheilizad
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  2. Mehdi Adib
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  3. Sami Sajjadifar
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Corresponding author

Correspondence to Mehdi Soheilizad.

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Soheilizad, M., Adib, M. & Sajjadifar, S. One-pot and solvent-free synthesis of aliphatic and aromatic 1H-indazolo[2,1-b]phthalazinetriones catalyzed by boron sulfonic acid. Monatsh Chem 145, 1353–1356 (2014). https://doi.org/10.1007/s00706-014-1194-9

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  • DOI: https://doi.org/10.1007/s00706-014-1194-9

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