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A ring opening reaction of 2-hetaryl-2-(tetrahydro-2-furanylidene)acetonitriles with amino acids

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Abstract

The ring opening reactions of 2-hetaryl-2-(tetrahydro-2-furanylidene)acetonitriles with α-, β-, γ-, ε-amino acids and alkyl esters of α-amino acids as N-nucleophiles have been investigated. New functionalized amino acid derivatives containing the heterocyclic moiety have been obtained and their reactions with electrophilic and nucleophilic agents have been studied.

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Authors and Affiliations

  1. Department of Chemistry, National Kyiv Taras Shevchenko University, 64 Volodymyrska st, 01601, Kyiv, Ukraine

    O. V. Khilya, D. S. Milokhov, V. Yu. Postupalenko, A. V. Turov & Y. M. Volovenko

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  1. O. V. Khilya
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  2. D. S. Milokhov
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  3. V. Yu. Postupalenko
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  4. A. V. Turov
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  5. Y. M. Volovenko
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Correspondence to O. V. Khilya.

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Khilya, O.V., Milokhov, D.S., Postupalenko, V.Y. et al. A ring opening reaction of 2-hetaryl-2-(tetrahydro-2-furanylidene)acetonitriles with amino acids. Monatsh Chem 144, 1071–1079 (2013). https://doi.org/10.1007/s00706-013-0967-x

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  • DOI: https://doi.org/10.1007/s00706-013-0967-x

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