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New method for the synthesis of 2-hetaryl-2-(1-R-pyrrolidin-2-ylidene)acetonitriles

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New method was developed for the synthesis of 2-hetaryl-2-(1-R-pyrrolidin-2-ylidene)acetonitriles by using a three-component condensation of hetarylacetonitrile, phosphorus oxychloride, and 1-R-pyrrolidin-2-one. This method is applicable to the synthesis of β-enaminonitriles containing azoles and six-membered azaheteroaromatic rings at the α-position relative to the nitrile group.

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  • 07 June 2018

    The name of the first author should read Elena A. Kuleshova.

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Authors and Affiliations

  1. Taras Shevchenko National University of Kyiv, 64/13 Volodymyrska St., Kyiv, 01601, Ukraine

    Olena A. Kuleshova, Olga V. Khilya & Yulian M. Volovenko

Authors
  1. Olena A. Kuleshova
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  2. Olga V. Khilya
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  3. Yulian M. Volovenko
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Corresponding author

Correspondence to Olena A. Kuleshova.

Additional information

A Supplementary information file containing 1H and 13С NMR spectra of compounds 1а–е is available at the journal website at http://link.springer.com/journal/10593.

Translated from Khimiya Geterotsiklicheskikh Soedinenii, 2018, 54(1), 83–85

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Kuleshova, O.A., Khilya, O.V. & Volovenko, Y.M. New method for the synthesis of 2-hetaryl-2-(1-R-pyrrolidin-2-ylidene)acetonitriles. Chem Heterocycl Comp 54, 83–85 (2018). https://doi.org/10.1007/s10593-018-2234-x

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  • DOI: https://doi.org/10.1007/s10593-018-2234-x

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