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Dipeptides with 3-(trimethylstannyl)alanine building blocks: synthesis, characterization, and reactivity

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Abstract

3-(Trimethylstannyl)alanine esters containing a free amino group react with different N-benzoyloxycarbonyl amino acids in the presence of N,N′-dicyclohexylcarbodiimide to yield new dipeptides with β-(trimethylstannyl)alanine building blocks. Reactions at the stannyl group were studied in more detail in two glycyl alaninates. Their reaction with Me3SnCl without solvent yields the chlorostannyl-substituted compounds. The glycyl alaninates react with two equivalents of bromine to give the dibromostannylated compounds.

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  1. Martin-Luther-Universität Halle, Biozentrum, 06099, Halle, Germany

    Karin Dölling

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  1. Karin Dölling
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Correspondence to Karin Dölling.

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Dölling, K. Dipeptides with 3-(trimethylstannyl)alanine building blocks: synthesis, characterization, and reactivity. Monatsh Chem 144, 729–734 (2013). https://doi.org/10.1007/s00706-012-0902-6

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  • DOI: https://doi.org/10.1007/s00706-012-0902-6

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