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Synthesis of flavanones, azaflavanones, and thioflavanones catalyzed by PMA-SiO2 as a mild, efficient, and reusable catalyst

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Abstract

Cyclization of a variety of chalcones to flavanones catalyzed by 1 mol% phosphomolybdic acid (PMA) supported on silica as a mild, efficient, and reusable catalyst was carried out in high yields. PMA-SiO2 is an efficient, inexpensive, and green catalyst which gave high conversion yields and could be recycled up to three times without significant loss in activity.

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Acknowledgments

R.S. and M.Y. thank the University of Malaya for their fellowships, and the authors acknowledge the Malaysian Ministry of Science, Technology, and Innovation (MOSTI) through IPharm for grant no. 53-02-03-1049.

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Authors and Affiliations

  1. Department of Chemistry, University of Malaya, 50603, Kuala Lumpur, Malaysia

    Raghavendra Sakirolla, Marzieh Yaeghoobi & Noorsaadah Abd. Rahman

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  1. Raghavendra Sakirolla
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  2. Marzieh Yaeghoobi
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  3. Noorsaadah Abd. Rahman
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Correspondence to Noorsaadah Abd. Rahman.

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Sakirolla, R., Yaeghoobi, M. & Abd. Rahman, N. Synthesis of flavanones, azaflavanones, and thioflavanones catalyzed by PMA-SiO2 as a mild, efficient, and reusable catalyst. Monatsh Chem 143, 797–800 (2012). https://doi.org/10.1007/s00706-011-0663-7

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  • DOI: https://doi.org/10.1007/s00706-011-0663-7

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