Abstract
An effective one-pot three-component route to 4(3H)-quinazolinones from commercially available starting materials is reported. Thus, isatoic anhydride reacted with ammonium acetate or primary amines and aldehydes in the presence of iodine to produce the corresponding quinazolinone derivatives in moderate to good yields.
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The authors would like to acknowledge financial support from the Research Council of Shahid Beheshti University.
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Dabiri, M., Salehi, P., Bahramnejad, M. et al. A practical and versatile approach toward a one-pot synthesis of 2,3-disubstituted 4(3H)-quinazolinones. Monatsh Chem 141, 877–881 (2010). https://doi.org/10.1007/s00706-010-0341-1
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DOI: https://doi.org/10.1007/s00706-010-0341-1