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Synthesis and Reactions of 5-Amino-3-(3-methyl-5-oxo-1-phenyl-2-pyrazolin-4-yl)-7-phenyl-7H-thiazolo[3,2-a]pyrimidine-6-carbonitrile

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Summary.

5-Amino-3-(3-methyl-5-oxo-1-phenyl-2-pyrazolin-4-yl)-7-phenyl-7H-thiazolo[3,2-a]pyrimidine-6-carbonitrile was synthesized via the reaction of 4-(2-aminothiazol-4-yl)-3-methyl-1-phenyl-2-pyrazolin-5-one with benzylidene malononitrile and was then transformed to related fused heterocyclic systems. The antifungal and antibacterial studies revealed in some cases excellent biocidal properties.

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Authors and Affiliations

  1. Chemistry Department, Faculty of Science, Assiut University, Assiut, Egypt

    Mohamed Salah K. Youssef & Ahmed A. Omar

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  1. Mohamed Salah K. Youssef
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  2. Ahmed A. Omar
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Correspondence to Mohamed Salah K. Youssef.

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Youssef, M., Omar, A. Synthesis and Reactions of 5-Amino-3-(3-methyl-5-oxo-1-phenyl-2-pyrazolin-4-yl)-7-phenyl-7H-thiazolo[3,2-a]pyrimidine-6-carbonitrile. Monatsh. Chem. 138, 989–995 (2007). https://doi.org/10.1007/s00706-007-0703-5

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  • DOI: https://doi.org/10.1007/s00706-007-0703-5

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