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Synthesis and Biological Activity of 6-(1,3-Benzoxazol-2-Yl)-5-Methylthieno-[2,3-d]Pyrimidines

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Pharmaceutical Chemistry Journal Aims and scope

An approach to the synthesis of new 6-(1,3-benzoxazol-2-yl)-5-methylthieno[2,3-d]pyrimidin-4(3H)-ones and their 4-thioanalogs was developed. Some of the synthesized compounds exhibited antimicrobial activity against strains of Bacillus subtilis bacteria and Candida albicans fungi.

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Authors and Affiliations

  1. National University of Pharmacy, 53 Pushkinskaya St., Kharkiv, 61002, Ukraine

    S. V. Vlasov, S. N. Kovalenko, E. B. Lenitskaya & V. P. Chernykh

  2. I. I. Mechnikov Institute of Microbiology and Immunology, National Academy of Medical Sciences of Ukraine, 14 – 16 Pushkinskaya St., Kharkiv, 61057, Ukraine

    T. P. Osolodchenko

Authors
  1. S. V. Vlasov
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  2. S. N. Kovalenko
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  3. T. P. Osolodchenko
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  4. E. B. Lenitskaya
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  5. V. P. Chernykh
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Corresponding author

Correspondence to S. V. Vlasov.

Additional information

Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 52, No. 6, pp. 22 – 25, June, 2018.

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Vlasov, S.V., Kovalenko, S.N., Osolodchenko, T.P. et al. Synthesis and Biological Activity of 6-(1,3-Benzoxazol-2-Yl)-5-Methylthieno-[2,3-d]Pyrimidines. Pharm Chem J 52, 510–514 (2018). https://doi.org/10.1007/s11094-018-1850-1

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  • DOI: https://doi.org/10.1007/s11094-018-1850-1

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