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Synthesis of Highly Functionalized Isoxazolinediones from One-pot Reaction of Alkylidene Meldrum’s Acid with Alkyl Isocyanides in the Presence of Arylhydroxylamines

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Summary.

Alkyl isocyanides undergo a smooth reaction with alkylidene Meldrum’s acids in the presence of arylhydroxylamines to produce N 1-alkyl-2-(3,5-dioxo-2-aryltetrahydro-4-isoxazolyl)alkanamides in high yields.

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Authors and Affiliations

  1. Faculty of Chemistry, Tarbiat Moallem University, Tehran, Iran

    Azizollah Habibi & Leyla Mousavifar

  2. Chemistry Department, Tarbiat Modarres University, Tehran, Iran

    Issa Yavari

  3. Chemistry Department, Guilan University, Rasht, Guilan, Iran

    Leyla Mousavifar & Mohammad R. Yazdanbakhsh

Authors
  1. Azizollah Habibi
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  2. Leyla Mousavifar
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  3. Issa Yavari
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  4. Mohammad R. Yazdanbakhsh
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Correspondence to Issa Yavari.

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Habibi, A., Mousavifar, L., Yavari, I. et al. Synthesis of Highly Functionalized Isoxazolinediones from One-pot Reaction of Alkylidene Meldrum’s Acid with Alkyl Isocyanides in the Presence of Arylhydroxylamines. Monatsh. Chem. 138, 603–606 (2007). https://doi.org/10.1007/s00706-007-0630-5

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  • DOI: https://doi.org/10.1007/s00706-007-0630-5

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