Skip to main content
SpringerLink
Log in

A Coupling Reaction of 4-Amino-5-mercapto- 3-substituted-1,2,4-triazoles to Generate Symmetrically Substituted Hydrazines

  • Published:
Monatshefte für Chemie / Chemical Monthly Aims and scope Submit manuscript

Summary.

A novel coupling reaction of 4-amino-5-mercapto-3-substituted-1,2,4-triazoles to generate symmetrically substituted hydrazines, N,N′-bis(5-mercapto-3-substituted-1,2,4-triazol-4-yl)hydrazines was unexpectedly observed. Five examples are presented to demonstrate this reaction. All isolated products were unambiguously characterized.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  • JR Maxwell DA Wasdahl AC Wolfson V Stenberg (1984) J Med Chem 27 1565 Occurrence Handle10.1021/jm00378a007 Occurrence Handle1:CAS:528:DyaL2cXmtlSnsLs%3D

    Article  CAS  Google Scholar 

  • BV Chiara M Maurizio CA Augusto G Mario (1998) J Heterocyclic Chem 35 29

    Google Scholar 

  • M Couderchet J Schmalfub P Boger (1998) Pestic Sci 52 381 Occurrence Handle10.1002/(SICI)1096-9063(199804)52:4<381::AID-PS735>3.0.CO;2-8 Occurrence Handle1:CAS:528:DyaK1cXis1KnsLk%3D

    Article  CAS  Google Scholar 

  • Triazoles 1 were readily prepared according to the earlier reports, Sasaki T, Ito E (1981) J Heterocyclic Chem 18: 1353; Reid JR, Heindel ND (1976) J Heterocyclic Chem 13: 925

    Google Scholar 

  • Compound 2 was readily prepared by the well-known Pummerer rearrangement according to Russell GA, Mikol GJ (1966) J Am Chem Soc 88: 5498

  • This conclusion has been verified unambiguously by X-ray diffraction method. Please see our previous research result concerning a similar tautomerism for reference, Wen LR, Li GQ, Li M, Jing SX, Zhang SS (2003) Chinese J Structural Chem 22: 529

Download references

Author information

Authors and Affiliations

  1. College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, 266042, Qingdao, P.R. China

    Ming Li, Guilong Zhao, Lirong Wen & Xiao Wang

  2. State Key Laboratory of Elemento-Organic Chemistry, Nankai University, 300071, Tianjin, P.R. China

    Xiaomao Zou & Huazheng Yang

Authors
  1. Ming Li
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Guilong Zhao
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Lirong Wen
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Xiao Wang
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Xiaomao Zou
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Huazheng Yang
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Ming Li.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Li, M., Zhao, G., Wen, L. et al. A Coupling Reaction of 4-Amino-5-mercapto- 3-substituted-1,2,4-triazoles to Generate Symmetrically Substituted Hydrazines. Monatsh. Chem. 136, 2045–2049 (2005). https://doi.org/10.1007/s00706-005-0372-1

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00706-005-0372-1

Search

Navigation