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4-Aminobicyclo[2.2.2]octan-2-ones and -ols via Enamine Intermediates

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Monatshefte für Chemie / Chemical Monthly Aims and scope Submit manuscript

Summary.

The synthesis of new bicyclo[2.2.2]octane derivatives is described and their structures were established by NMR experiments. All compounds were tested in in vitro assays for their activities against causative organisms of malaria and African sleeping sickness and compared to those of former synthesized compounds.

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Authors and Affiliations

  1. Institute of Pharmaceutical Sciences, Pharmaceutical Chemistry, Karl-Franzens-University of Graz, A-8010, Graz, Austria

    Werner Seebacher & Robert Weis

  2. Swiss Tropical Institute, CH-4002, Basel, Switzerland

    Marcel Kaiser & Reto Brun

  3. Institute of Chemical Technology of Organic Materials, Erzherzog-Johann University, A-8010, Graz, Austria

    Robert Saf

Authors
  1. Werner Seebacher
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  2. Marcel Kaiser
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  3. Reto Brun
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  4. Robert Saf
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  5. Robert Weis
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Corresponding author

Correspondence to Werner Seebacher.

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Seebacher, W., Kaiser, M., Brun, R. et al. 4-Aminobicyclo[2.2.2]octan-2-ones and -ols via Enamine Intermediates. Monatshefte für Chemie 136, 625–634 (2005). https://doi.org/10.1007/s00706-004-0264-9

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  • DOI: https://doi.org/10.1007/s00706-004-0264-9

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